Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387207031> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4387207031 endingPage "e264" @default.
- W4387207031 startingPage "e263" @default.
- W4387207031 abstract "To evaluate treatment related toxicity in patients with collagen vascular disorder (CVD) undergoing contemporary radiotherapy.This is a retrospective cohort study of patients with CVD undergoing radiation therapy from 2005 to 2022 at a single institution. CVD evaluated included lupus, scleroderma, rheumatoid arthritis, and Sjogren's syndrome or other nonspecific CVD. Patient characteristics, diagnostic and treatment information were extracted from various institutional EMR systems. This study was designated the status of EXEMPT by the institutional IRB.A total of 40 patients undergoing 44 treatment courses with a minimum follow up of 3 months are included in this study. Among the 40 patients identified, 8 were male and 32 were female, with a median age of 62 (range, 17 to 88). Out of the 40 patients in our study, 30 were diagnosed with lupus, 6 with scleroderma, and 4 with other CVDs. In regard to treatments, 38 were performed for malignant conditions and 6 for benign conditions. Treatment locations included 10 to the head and neck region, 16 to the thorax, 6 to the pelvis, and 11 to the skin, soft tissue, or other locations. Treatment modalities were protons for 6 treatments, photons for 33 treatments, and electrons for 5 treatments. Ten patients also received chemotherapy concurrently. Median follow up time was 33.2 months. Table 1 illustrates the extent of skin and subcutaneous reaction by treatment region and radiation doses. One patient, who had Grade 3 radiation dermatitis, underwent a short break in RT due to severity of symptoms. Three patients experienced severe, painful lupus flares during the course of RT, but were managed by medication; however, one was hospitalized due to severe pain and blistering of the skin. Two patients experienced radiation related dermal thickening and fibrosis of the treatment area skin.Contemporary radiation techniques may allow for the treatment of patients with significant collagen vascular disorders. In general, the treatments are well tolerated with the most common side effects relating to skin and subcutaneous tissue or flare up in generalized symptoms. However, the time to resolution of these symptoms may be longer and requires diligent care. Caution should be used in treating patients with CVD." @default.
- W4387207031 created "2023-09-30" @default.
- W4387207031 creator A5025967381 @default.
- W4387207031 creator A5035731832 @default.
- W4387207031 creator A5041683454 @default.
- W4387207031 creator A5051361749 @default.
- W4387207031 creator A5056448816 @default.
- W4387207031 creator A5064627939 @default.
- W4387207031 creator A5080709444 @default.
- W4387207031 date "2023-10-01" @default.
- W4387207031 modified "2023-10-17" @default.
- W4387207031 title "Adverse Events Relating to Radiation Therapy in Patients with Collagen Vascular Disorders" @default.
- W4387207031 doi "https://doi.org/10.1016/j.ijrobp.2023.06.1220" @default.
- W4387207031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37785005" @default.
- W4387207031 hasPublicationYear "2023" @default.
- W4387207031 type Work @default.
- W4387207031 citedByCount "0" @default.
- W4387207031 crossrefType "journal-article" @default.
- W4387207031 hasAuthorship W4387207031A5025967381 @default.
- W4387207031 hasAuthorship W4387207031A5035731832 @default.
- W4387207031 hasAuthorship W4387207031A5041683454 @default.
- W4387207031 hasAuthorship W4387207031A5051361749 @default.
- W4387207031 hasAuthorship W4387207031A5056448816 @default.
- W4387207031 hasAuthorship W4387207031A5064627939 @default.
- W4387207031 hasAuthorship W4387207031A5080709444 @default.
- W4387207031 hasConcept C105702510 @default.
- W4387207031 hasConcept C126322002 @default.
- W4387207031 hasConcept C141071460 @default.
- W4387207031 hasConcept C142724271 @default.
- W4387207031 hasConcept C16005928 @default.
- W4387207031 hasConcept C167135981 @default.
- W4387207031 hasConcept C180032290 @default.
- W4387207031 hasConcept C197934379 @default.
- W4387207031 hasConcept C2776670291 @default.
- W4387207031 hasConcept C2776912625 @default.
- W4387207031 hasConcept C2777575956 @default.
- W4387207031 hasConcept C2779075594 @default.
- W4387207031 hasConcept C2779121184 @default.
- W4387207031 hasConcept C2779134260 @default.
- W4387207031 hasConcept C2779967694 @default.
- W4387207031 hasConcept C509974204 @default.
- W4387207031 hasConcept C71924100 @default.
- W4387207031 hasConcept C97834683 @default.
- W4387207031 hasConceptScore W4387207031C105702510 @default.
- W4387207031 hasConceptScore W4387207031C126322002 @default.
- W4387207031 hasConceptScore W4387207031C141071460 @default.
- W4387207031 hasConceptScore W4387207031C142724271 @default.
- W4387207031 hasConceptScore W4387207031C16005928 @default.
- W4387207031 hasConceptScore W4387207031C167135981 @default.
- W4387207031 hasConceptScore W4387207031C180032290 @default.
- W4387207031 hasConceptScore W4387207031C197934379 @default.
- W4387207031 hasConceptScore W4387207031C2776670291 @default.
- W4387207031 hasConceptScore W4387207031C2776912625 @default.
- W4387207031 hasConceptScore W4387207031C2777575956 @default.
- W4387207031 hasConceptScore W4387207031C2779075594 @default.
- W4387207031 hasConceptScore W4387207031C2779121184 @default.
- W4387207031 hasConceptScore W4387207031C2779134260 @default.
- W4387207031 hasConceptScore W4387207031C2779967694 @default.
- W4387207031 hasConceptScore W4387207031C509974204 @default.
- W4387207031 hasConceptScore W4387207031C71924100 @default.
- W4387207031 hasConceptScore W4387207031C97834683 @default.
- W4387207031 hasIssue "2" @default.
- W4387207031 hasLocation W43872070311 @default.
- W4387207031 hasLocation W43872070312 @default.
- W4387207031 hasOpenAccess W4387207031 @default.
- W4387207031 hasPrimaryLocation W43872070311 @default.
- W4387207031 hasRelatedWork W2064502443 @default.
- W4387207031 hasRelatedWork W2422066212 @default.
- W4387207031 hasRelatedWork W2470927495 @default.
- W4387207031 hasRelatedWork W2473788747 @default.
- W4387207031 hasRelatedWork W2768176932 @default.
- W4387207031 hasRelatedWork W3141388109 @default.
- W4387207031 hasRelatedWork W3181770747 @default.
- W4387207031 hasRelatedWork W4318000910 @default.
- W4387207031 hasRelatedWork W46229524 @default.
- W4387207031 hasRelatedWork W93747897 @default.
- W4387207031 hasVolume "117" @default.
- W4387207031 isParatext "false" @default.
- W4387207031 isRetracted "false" @default.
- W4387207031 workType "article" @default.