FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387207906> ?p ?o ?g. }

• W4387207906 endingPage "e5" @default.
• W4387207906 startingPage "e5" @default.
• W4387207906 abstract "Patients with N2 non-small cell lung cancer (NSCLC) were heterogeneous groups and required further stratification. The International Society for the Study of Lung Cancer (IASLC) added new descriptors of three sub-stages for stage N2 NSCLC: N2 at a single station without N1 involvement (N2a1), N2 at a single station with N1 involvement (N2a2), and N2 at multiple stations (N2b). This study aimed to investigate the efficacy of postoperative radiotherapy (PORT) for patients with these N2 descriptors.Patients with histologically confirmed NSCLC after complete resection and divided into PORT group and non-PORT group. The primary endpoint was DFS. The second endpoints were overall survival (OS) and locoregional recurrence-free survival (LRFS). Propensity-score matching (PSM) of baseline characteristics between the PORT and non-PORT groups was used for validation.Totally 1832 patients were enrolled, including 308 N2a1 patients, 682 N2a2 patients, and 842 N2b patients. The median follow-up time was 50.1 months. The survival outcomes of the PORT and non-PORT groups before PSM were shown in Table 1. For patients with N2a1, PORT could not improve the DFS (median DFS of the PORT group and the non-PORT group: not reached vs. 46.8 months, P = 0.41), OS (P = 0.85), or LRFS (P = 0.32), which were consistent with the multivariate analysis and data after the PSM. For patients with N2a2, PORT significantly improved the DFS (median DFS 29.7 vs. 22.2 months, P = 0.02), OS (P = 0.03), and LRFS (P = 0.01). The multivariate analysis and data after the PSM confirmed the benefits in DFS and LRFS, but no benefit was observed in OS (multivariate analysis: HR 0.79, P = 0.18; median OS after PSM: 103.7 vs. 63.1 months, P = 0.34). For patients with N2b, PORT could not improve the DFS (median DFS 20.6 vs. 21.2 months, P = 0.39) but significantly improved the OS (P<0.001) and LRFS (P<0.001). However, the multivariate analysis showed that PORT significantly improved DFS (HR 0.81, P = 0.03), consistent with the data after the PSM (median DFS 20.6 and 17.6 months, P = 0.04).PORT significantly improved the DFS and LRFS in patients with N2a2 and significantly improved the DFS, LRFS, and OS in patients with N2b. Patients with N2a1 could not benefit from PORT." @default.
• W4387207906 created "2023-09-30" @default.
• W4387207906 creator A5001945317 @default.
• W4387207906 creator A5006424190 @default.
• W4387207906 creator A5006458345 @default.
• W4387207906 creator A5008659449 @default.
• W4387207906 creator A5021683705 @default.
• W4387207906 creator A5023892880 @default.
• W4387207906 creator A5032664808 @default.
• W4387207906 creator A5033429378 @default.
• W4387207906 creator A5037677450 @default.
• W4387207906 creator A5040193086 @default.
• W4387207906 creator A5042341005 @default.
• W4387207906 creator A5043940359 @default.
• W4387207906 creator A5045878156 @default.
• W4387207906 creator A5049812372 @default.
• W4387207906 creator A5050762950 @default.
• W4387207906 creator A5063263317 @default.
• W4387207906 creator A5067268351 @default.
• W4387207906 creator A5073304157 @default.
• W4387207906 creator A5081853954 @default.
• W4387207906 creator A5089768060 @default.
• W4387207906 date "2023-10-01" @default.
• W4387207906 modified "2023-10-04" @default.
• W4387207906 title "Efficacy of Postoperative Radiotherapy for Patients with New N2 Descriptors of Subclassification in Completely Resected Non-Small Cell Lung Cancer: A Real-World Study" @default.
• W4387207906 doi "https://doi.org/10.1016/j.ijrobp.2023.06.657" @default.
• W4387207906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37785570" @default.
• W4387207906 hasPublicationYear "2023" @default.
• W4387207906 type Work @default.
• W4387207906 citedByCount "0" @default.
• W4387207906 crossrefType "journal-article" @default.
• W4387207906 hasAuthorship W4387207906A5001945317 @default.
• W4387207906 hasAuthorship W4387207906A5006424190 @default.
• W4387207906 hasAuthorship W4387207906A5006458345 @default.
• W4387207906 hasAuthorship W4387207906A5008659449 @default.
• W4387207906 hasAuthorship W4387207906A5021683705 @default.
• W4387207906 hasAuthorship W4387207906A5023892880 @default.
• W4387207906 hasAuthorship W4387207906A5032664808 @default.
• W4387207906 hasAuthorship W4387207906A5033429378 @default.
• W4387207906 hasAuthorship W4387207906A5037677450 @default.
• W4387207906 hasAuthorship W4387207906A5040193086 @default.
• W4387207906 hasAuthorship W4387207906A5042341005 @default.
• W4387207906 hasAuthorship W4387207906A5043940359 @default.
• W4387207906 hasAuthorship W4387207906A5045878156 @default.
• W4387207906 hasAuthorship W4387207906A5049812372 @default.
• W4387207906 hasAuthorship W4387207906A5050762950 @default.
• W4387207906 hasAuthorship W4387207906A5063263317 @default.
• W4387207906 hasAuthorship W4387207906A5067268351 @default.
• W4387207906 hasAuthorship W4387207906A5073304157 @default.
• W4387207906 hasAuthorship W4387207906A5081853954 @default.
• W4387207906 hasAuthorship W4387207906A5089768060 @default.
• W4387207906 hasConcept C119599485 @default.
• W4387207906 hasConcept C126322002 @default.
• W4387207906 hasConcept C127413603 @default.
• W4387207906 hasConcept C141071460 @default.
• W4387207906 hasConcept C143998085 @default.
• W4387207906 hasConcept C146357865 @default.
• W4387207906 hasConcept C151730666 @default.
• W4387207906 hasConcept C168563851 @default.
• W4387207906 hasConcept C17923572 @default.
• W4387207906 hasConcept C203092338 @default.
• W4387207906 hasConcept C2776256026 @default.
• W4387207906 hasConcept C3019894029 @default.
• W4387207906 hasConcept C32802771 @default.
• W4387207906 hasConcept C38180746 @default.
• W4387207906 hasConcept C509974204 @default.
• W4387207906 hasConcept C71924100 @default.
• W4387207906 hasConcept C86803240 @default.
• W4387207906 hasConceptScore W4387207906C119599485 @default.
• W4387207906 hasConceptScore W4387207906C126322002 @default.
• W4387207906 hasConceptScore W4387207906C127413603 @default.
• W4387207906 hasConceptScore W4387207906C141071460 @default.
• W4387207906 hasConceptScore W4387207906C143998085 @default.
• W4387207906 hasConceptScore W4387207906C146357865 @default.
• W4387207906 hasConceptScore W4387207906C151730666 @default.
• W4387207906 hasConceptScore W4387207906C168563851 @default.
• W4387207906 hasConceptScore W4387207906C17923572 @default.
• W4387207906 hasConceptScore W4387207906C203092338 @default.
• W4387207906 hasConceptScore W4387207906C2776256026 @default.
• W4387207906 hasConceptScore W4387207906C3019894029 @default.
• W4387207906 hasConceptScore W4387207906C32802771 @default.
• W4387207906 hasConceptScore W4387207906C38180746 @default.
• W4387207906 hasConceptScore W4387207906C509974204 @default.
• W4387207906 hasConceptScore W4387207906C71924100 @default.
• W4387207906 hasConceptScore W4387207906C86803240 @default.
• W4387207906 hasIssue "2" @default.
• W4387207906 hasLocation W43872079061 @default.
• W4387207906 hasLocation W43872079062 @default.
• W4387207906 hasOpenAccess W4387207906 @default.
• W4387207906 hasPrimaryLocation W43872079061 @default.
• W4387207906 hasRelatedWork W2009137688 @default.
• W4387207906 hasRelatedWork W2089892177 @default.
• W4387207906 hasRelatedWork W2356484369 @default.
• W4387207906 hasRelatedWork W2357352706 @default.
• W4387207906 hasRelatedWork W2363865786 @default.
• W4387207906 hasRelatedWork W2407189953 @default.
• W4387207906 hasRelatedWork W4207026578 @default.
• W4387207906 hasRelatedWork W4285492859 @default.

• next