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- W4387220417 abstract "Abstract Background There is a dearth of robust evidence regarding the correlation between psoriasis with maternal and neonatal outcomes, making it challenging to establish definitive recommendations for the management of these patients. This systematic review and meta-analysis aimed to review the evidence with regard to the impact of maternal psoriasis on maternal and neonatal outcomes. Methods Following the PRISMA guideline, a systematic search of English articles using PubMed, Embase, Scopus, ScienceDirect, Web of Science, Google Scholar, and the Cochrane Library was conducted. The search was performed from inception to 22 nd of May 2022. Result A significant association was observed between psoriasis and maternal outcomes, including cesarean delivery [OR = 1.25 (95% CI: 1.13–1.30, p -value = 0.001)], (pre)eclampsia [OR = 1.29 (95% CI: 1.15–1.44, p -value = 0.0001)], gestational diabetes [Odds Ratio (OR) = 1.23 (95% Confidence Intervals (CI): 1.15–1.30, p -value = 0.001)], gestational hypertension [OR = 1.31 (95% CI: 1.18–1.45, p -value = 0.001)] and preterm birth [OR = 1.22 (95% CI: 1.10–1.35, p -value = 0.001)]. Also, there was a significant association between psoriasis and neonatal outcomes, including small for gestational age [OR = 1.07 (95% CI: 1.02–1.11, p -value = 0.053)], low birth weight [OR = 1.19 (95% CI: 1.02–1.38, p -value = 0.001)] and stillbirth [OR = 1.27 (95% CI: 1.04–1.55, p -value = 0.023)]. Conclusion Maternal psoriasis could negatively impact maternal and neonatal outcomes. Our results strengthen the importance of close monitoring of the mothers’ psoriasis status before and during pregnancy." @default.
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- W4387220417 date "2023-09-30" @default.
- W4387220417 modified "2023-10-16" @default.
- W4387220417 title "Impact of maternal psoriasis on adverse maternal and neonatal outcomes: a systematic review and meta-analysis" @default.
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- W4387220417 doi "https://doi.org/10.1186/s12884-023-06006-5" @default.
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