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- W4387223535 abstract "The dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic dysfunction in the pathogenesis and treatment of DKD, it is essential to thoroughly examine the available data on this topic. Accordingly, the aim of this review is to provide a comprehensive appraisal of the role of intraglomerular hemodynamic dysfunction in the development of DKD and the effects of current therapies used to mitigate DKD. Through this analysis, we can gain a deeper understanding of the complex pathogenesis of DKD and potentially discover new avenues for tailored therapeutic management of patients with DKD." @default.
- W4387223535 created "2023-10-01" @default.
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- W4387223535 date "2023-09-01" @default.
- W4387223535 modified "2023-10-17" @default.
- W4387223535 title "Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact" @default.
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- W4387223535 doi "https://doi.org/10.1016/j.lpm.2023.104175" @default.
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