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• W4387223567 endingPage "e19733" @default.
• W4387223567 startingPage "e19733" @default.
• W4387223567 abstract "The taste of food plays a crucial role in determining what and how much we eat. Thus, interventions that temporarily block sweet taste receptors offer a promising approach to addressing unhealthy behaviours associated with sugary foods. However, the relationship between reduced sweet taste response and food consumption remains unclear, with contradictory findings. Certain studies suggest that a diminished perception of sweetness leads to a sense of fullness and results in reduced food intake, while others suggest the opposite effect. To shed some light, our systematic review looked into the relationship between diminished sweet taste response and food consumption by examining the effects of bioactive compounds that experimentally inhibit sweetness in healthy individuals. This review was registered in the International Prospective Register of Systematic Reviews and conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and the Scottish Intercollegiate Guidelines Network, and covered original papers included in Web of Science, PubMed, Scopus, Food Science Source and Food Science and technology abstracts. We identified 33 peer-reviewed English-language studies that fit the topic and met the inclusion criteria. The current literature predominantly focuses on the immediate impact of oral gymnemic acids, failing to provide preliminary evidence in support of the specific threshold hypothesis, above which food consumption decreases and below which the opposite effect occurs. Additionally, there was inconsistency in the findings regarding the short-term desire to eat following sweetness inhibition. Considering the downstream effects on energy intake and their clinical applications, further research is needed to clarify both the acute within-session effects (i.e., not wanting any more now) and the longer-term effects (i.e., deciding not to start eating) linked to oral sweet-taste-suppressing compounds." @default.
• W4387223567 created "2023-10-01" @default.
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• W4387223567 date "2023-10-01" @default.
• W4387223567 modified "2023-10-18" @default.
• W4387223567 title "Suppression of sweet taste-related responses by plant-derived bioactive compounds and eating. Part I: A systematic review in humans" @default.
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• W4387223567 doi "https://doi.org/10.1016/j.heliyon.2023.e19733" @default.
• W4387223567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37817998" @default.
• W4387223567 hasPublicationYear "2023" @default.
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