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- W4387230444 abstract "Interoception, the representation of the body’s internal state, is increasingly recognized for informing subjective wellbeing and promoting regulatory behavior. However, few empirical reports characterize interoceptive neural networks, and fewer demonstrate changes to these networks in response to an efficacious intervention. Using a two-group randomized controlled trial, this pilot study explored within-participant neural plasticity in interoceptive networks following Mindful Awareness in Body-oriented Therapy (MABT). Participants (N = 22) were assigned to either 8 weeks of MABT or to a no-treatment control and completed baseline and post-intervention assessments that included subjective interoceptive awareness (MAIA) and neuroimaging of an interoceptive awareness task. MABT was uniquely associated with insula deactivation, increased functional connectivity between the dorsal attention network and the somatomotor cortex, and connectivity changes correlated positively with changes in subjective interoception. Within the MABT group, changes in subjective interoception interacted with changes in a predefined anterior cingulate seed region to predict changes in right middle insula activity, a putative primary interoceptive representation region. While the small sample size requires the replication of findings, results suggest that interoceptive training enhances sensory–prefrontal connectivity, and that such changes are commensurate with enhanced interoceptive awareness." @default.
- W4387230444 created "2023-10-02" @default.
- W4387230444 creator A5013190260 @default.
- W4387230444 creator A5041765307 @default.
- W4387230444 creator A5080801332 @default.
- W4387230444 date "2023-09-30" @default.
- W4387230444 modified "2023-10-16" @default.
- W4387230444 title "Within-Person Modulation of Neural Networks following Interoceptive Awareness Training through Mindful Awareness in Body-Oriented Therapy (MABT): A Pilot Study" @default.
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- W4387230444 doi "https://doi.org/10.3390/brainsci13101396" @default.
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