FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387235087> ?p ?o ?g. }

• W4387235087 abstract "The pharmaceutical industry has shown keen interest in developing small-scale modular manufacturing systems for producing medicinal products. These systems offer agile and flexible manufacturing, and are well-suited for use in situations requiring rapid production of drugs such as pandemics and humanitarian disasters. The creation of such systems requires the development of modular facilities for making solid oral drug products. In recent years, however, the development of such facilities has seen limited progress. This study presents a development of a prototype modular system that uses drop on demand (DoD) printing to produce personalized solid oral drug products. The system's operation is demonstrated for manufacturing mini-tablets, a category of pediatric drug products, in continuous and semi-batch modes. In this process, the DoD printer is used to generate molten formulation drops that are solidified into mini-tablets. These dosages are then extracted, washed and dried in a continuous filtration and drying unit which is integrated with the printer. Process monitoring tools are also incorporated in the system to track the critical quality attributes of the product and the critical process parameters of the manufacturing operation in real time. Future areas of innovation are also proposed to improve this prototype unit and to enable the development of advanced drug manufacturing systems based on this platform." @default.
• W4387235087 created "2023-10-02" @default.
• W4387235087 creator A5006815808 @default.
• W4387235087 creator A5019951975 @default.
• W4387235087 creator A5027876445 @default.
• W4387235087 creator A5051055658 @default.
• W4387235087 creator A5057438733 @default.
• W4387235087 creator A5074623014 @default.
• W4387235087 date "2023-10-01" @default.
• W4387235087 modified "2023-10-16" @default.
• W4387235087 title "Developing a modular continuous drug product manufacturing system with real time quality assurance for producing pharmaceutical mini-tablets" @default.
• W4387235087 cites W2009249904 @default.
• W4387235087 cites W2073010988 @default.
• W4387235087 cites W2083259132 @default.
• W4387235087 cites W2087178073 @default.
• W4387235087 cites W2102045157 @default.
• W4387235087 cites W2112211764 @default.
• W4387235087 cites W2156636836 @default.
• W4387235087 cites W2157788227 @default.
• W4387235087 cites W2226944812 @default.
• W4387235087 cites W2292164259 @default.
• W4387235087 cites W2334592091 @default.
• W4387235087 cites W2473671049 @default.
• W4387235087 cites W2475442629 @default.
• W4387235087 cites W2511348188 @default.
• W4387235087 cites W2572621360 @default.
• W4387235087 cites W2734360120 @default.
• W4387235087 cites W2767874069 @default.
• W4387235087 cites W2789309081 @default.
• W4387235087 cites W2868238225 @default.
• W4387235087 cites W2964400531 @default.
• W4387235087 cites W2986254079 @default.
• W4387235087 cites W3196587156 @default.
• W4387235087 cites W3215724575 @default.
• W4387235087 cites W4206968096 @default.
• W4387235087 cites W4220782333 @default.
• W4387235087 cites W4256684293 @default.
• W4387235087 cites W4386226637 @default.
• W4387235087 doi "https://doi.org/10.1016/j.xphs.2023.09.024" @default.
• W4387235087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37788791" @default.
• W4387235087 hasPublicationYear "2023" @default.
• W4387235087 type Work @default.
• W4387235087 citedByCount "0" @default.
• W4387235087 crossrefType "journal-article" @default.
• W4387235087 hasAuthorship W4387235087A5006815808 @default.
• W4387235087 hasAuthorship W4387235087A5019951975 @default.
• W4387235087 hasAuthorship W4387235087A5027876445 @default.
• W4387235087 hasAuthorship W4387235087A5051055658 @default.
• W4387235087 hasAuthorship W4387235087A5057438733 @default.
• W4387235087 hasAuthorship W4387235087A5074623014 @default.
• W4387235087 hasConcept C101468663 @default.
• W4387235087 hasConcept C106436119 @default.
• W4387235087 hasConcept C111472728 @default.
• W4387235087 hasConcept C111919701 @default.
• W4387235087 hasConcept C117671659 @default.
• W4387235087 hasConcept C127413603 @default.
• W4387235087 hasConcept C138885662 @default.
• W4387235087 hasConcept C144133560 @default.
• W4387235087 hasConcept C162853370 @default.
• W4387235087 hasConcept C174998907 @default.
• W4387235087 hasConcept C178144697 @default.
• W4387235087 hasConcept C19351080 @default.
• W4387235087 hasConcept C204320433 @default.
• W4387235087 hasConcept C21547014 @default.
• W4387235087 hasConcept C21880701 @default.
• W4387235087 hasConcept C2524010 @default.
• W4387235087 hasConcept C2778618615 @default.
• W4387235087 hasConcept C2778938233 @default.
• W4387235087 hasConcept C2779530757 @default.
• W4387235087 hasConcept C2779652045 @default.
• W4387235087 hasConcept C33923547 @default.
• W4387235087 hasConcept C41008148 @default.
• W4387235087 hasConcept C524769229 @default.
• W4387235087 hasConcept C71924100 @default.
• W4387235087 hasConcept C78519656 @default.
• W4387235087 hasConcept C90673727 @default.
• W4387235087 hasConcept C98045186 @default.
• W4387235087 hasConcept C98274493 @default.
• W4387235087 hasConceptScore W4387235087C101468663 @default.
• W4387235087 hasConceptScore W4387235087C106436119 @default.
• W4387235087 hasConceptScore W4387235087C111472728 @default.
• W4387235087 hasConceptScore W4387235087C111919701 @default.
• W4387235087 hasConceptScore W4387235087C117671659 @default.
• W4387235087 hasConceptScore W4387235087C127413603 @default.
• W4387235087 hasConceptScore W4387235087C138885662 @default.
• W4387235087 hasConceptScore W4387235087C144133560 @default.
• W4387235087 hasConceptScore W4387235087C162853370 @default.
• W4387235087 hasConceptScore W4387235087C174998907 @default.
• W4387235087 hasConceptScore W4387235087C178144697 @default.
• W4387235087 hasConceptScore W4387235087C19351080 @default.
• W4387235087 hasConceptScore W4387235087C204320433 @default.
• W4387235087 hasConceptScore W4387235087C21547014 @default.
• W4387235087 hasConceptScore W4387235087C21880701 @default.
• W4387235087 hasConceptScore W4387235087C2524010 @default.
• W4387235087 hasConceptScore W4387235087C2778618615 @default.
• W4387235087 hasConceptScore W4387235087C2778938233 @default.
• W4387235087 hasConceptScore W4387235087C2779530757 @default.
• W4387235087 hasConceptScore W4387235087C2779652045 @default.
• W4387235087 hasConceptScore W4387235087C33923547 @default.
• W4387235087 hasConceptScore W4387235087C41008148 @default.

• next