FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387241754> ?p ?o ?g. }

• W4387241754 abstract "Castleman disease (CD) is a rare lymphoproliferative disorder of undetermined etiology. Unicentric CD (UCD) and multicentric CD (MCD) are two phenotypes of CD diagnosed by the histopathology of lymph nodes. We attempted to describe a pediatric CD cohort to optimize the management of this disease. We reviewed the medical records of pediatric patients diagnosed with CD between April, 2004, and October, 2022, at the Children's Hospital of Fudan University. Prognosis information was collected in January, 2023, by telephone inquiry. Twenty-two patients with UCD and 2 patients with MCD were identified, all with hyaline vascular (HV) type. The median ages at diagnosis were 10.75 years (IQR 8, 12.81) for UCD and 14.42 years (IQR 13.42, 15.42) for MCD. The most common lesion location of UCD was the neck (9/22, 40.91%) and abdomen (9/22, 40.91%). Systematic symptoms occurred on 10/22 (45.45%) patients with UCD and 1/2 (50%) patients with MCD, and abnormal laboratory indexes were detected in both. Resection and biopsy were performed on all patients. One out of two patients with MCD also received rituximab for upfront therapy. After a median of 4 years (IQR 1.5, 6) of follow-up time, the overall survival was 100% and the complete remission rate in UCD was 63%. There was no relapse or progression.Our series demonstrated that HV-UCD was the most common type in children. Resection and biopsy were used for both deterministic diagnoses and treatments. Despite the high possibility to develop systematic inflammation, children with CD showed promising outcomes.• Castleman disease is a rare lymphoproliferative disorder with limited cohort studies, especially in pediatrics. • The ubiquity of delayed confirmations and misdiagnoses points to a lack of knowledge about etiology and characteristics, which is a prerequisite for novel therapeutics.• We retrospectively reviewed and analyzed the clinical and pathological symptoms, laboratory and imaging features, and treatment outcomes of a Chinese pediatric cohort with Castleman disease. • Our work may improve the recognition and optimize the management of this rare disease in children." @default.
• W4387241754 created "2023-10-03" @default.
• W4387241754 creator A5007510504 @default.
• W4387241754 creator A5016814129 @default.
• W4387241754 creator A5019528308 @default.
• W4387241754 creator A5023026687 @default.
• W4387241754 creator A5024993083 @default.
• W4387241754 creator A5027835055 @default.
• W4387241754 creator A5029077264 @default.
• W4387241754 creator A5036392227 @default.
• W4387241754 creator A5051363890 @default.
• W4387241754 creator A5055977368 @default.
• W4387241754 creator A5079576759 @default.
• W4387241754 creator A5080545858 @default.
• W4387241754 creator A5085233592 @default.
• W4387241754 creator A5085420366 @default.
• W4387241754 date "2023-10-02" @default.
• W4387241754 modified "2023-10-03" @default.
• W4387241754 title "Clinical features and treatment outcomes of Castleman disease in children: a retrospective cohort in China" @default.
• W4387241754 cites W1987091861 @default.
• W4387241754 cites W2064801067 @default.
• W4387241754 cites W2099570557 @default.
• W4387241754 cites W2169031812 @default.
• W4387241754 cites W2169461745 @default.
• W4387241754 cites W2296827990 @default.
• W4387241754 cites W2572250031 @default.
• W4387241754 cites W2769119102 @default.
• W4387241754 cites W2889882574 @default.
• W4387241754 cites W2906800880 @default.
• W4387241754 cites W2913328040 @default.
• W4387241754 cites W2913717311 @default.
• W4387241754 cites W2968883182 @default.
• W4387241754 cites W3006713791 @default.
• W4387241754 cites W3016503434 @default.
• W4387241754 cites W3023502777 @default.
• W4387241754 cites W3036731143 @default.
• W4387241754 cites W3184061040 @default.
• W4387241754 cites W3195395058 @default.
• W4387241754 cites W4200079319 @default.
• W4387241754 cites W4210373414 @default.
• W4387241754 cites W4223576210 @default.
• W4387241754 cites W4225114727 @default.
• W4387241754 cites W4280555505 @default.
• W4387241754 cites W4296526509 @default.
• W4387241754 cites W4306168116 @default.
• W4387241754 cites W4310062077 @default.
• W4387241754 doi "https://doi.org/10.1007/s00431-023-05235-2" @default.
• W4387241754 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37782352" @default.
• W4387241754 hasPublicationYear "2023" @default.
• W4387241754 type Work @default.
• W4387241754 citedByCount "0" @default.
• W4387241754 crossrefType "journal-article" @default.
• W4387241754 hasAuthorship W4387241754A5007510504 @default.
• W4387241754 hasAuthorship W4387241754A5016814129 @default.
• W4387241754 hasAuthorship W4387241754A5019528308 @default.
• W4387241754 hasAuthorship W4387241754A5023026687 @default.
• W4387241754 hasAuthorship W4387241754A5024993083 @default.
• W4387241754 hasAuthorship W4387241754A5027835055 @default.
• W4387241754 hasAuthorship W4387241754A5029077264 @default.
• W4387241754 hasAuthorship W4387241754A5036392227 @default.
• W4387241754 hasAuthorship W4387241754A5051363890 @default.
• W4387241754 hasAuthorship W4387241754A5055977368 @default.
• W4387241754 hasAuthorship W4387241754A5079576759 @default.
• W4387241754 hasAuthorship W4387241754A5080545858 @default.
• W4387241754 hasAuthorship W4387241754A5085233592 @default.
• W4387241754 hasAuthorship W4387241754A5085420366 @default.
• W4387241754 hasBestOaLocation W43872417541 @default.
• W4387241754 hasConcept C126322002 @default.
• W4387241754 hasConcept C137627325 @default.
• W4387241754 hasConcept C167135981 @default.
• W4387241754 hasConcept C187212893 @default.
• W4387241754 hasConcept C2776054410 @default.
• W4387241754 hasConcept C2779134260 @default.
• W4387241754 hasConcept C71924100 @default.
• W4387241754 hasConcept C72563966 @default.
• W4387241754 hasConceptScore W4387241754C126322002 @default.
• W4387241754 hasConceptScore W4387241754C137627325 @default.
• W4387241754 hasConceptScore W4387241754C167135981 @default.
• W4387241754 hasConceptScore W4387241754C187212893 @default.
• W4387241754 hasConceptScore W4387241754C2776054410 @default.
• W4387241754 hasConceptScore W4387241754C2779134260 @default.
• W4387241754 hasConceptScore W4387241754C71924100 @default.
• W4387241754 hasConceptScore W4387241754C72563966 @default.
• W4387241754 hasLocation W43872417541 @default.
• W4387241754 hasLocation W43872417542 @default.
• W4387241754 hasOpenAccess W4387241754 @default.
• W4387241754 hasPrimaryLocation W43872417541 @default.
• W4387241754 hasRelatedWork W2079992490 @default.
• W4387241754 hasRelatedWork W2315085516 @default.
• W4387241754 hasRelatedWork W2412965123 @default.
• W4387241754 hasRelatedWork W2465854091 @default.
• W4387241754 hasRelatedWork W2603773853 @default.
• W4387241754 hasRelatedWork W2969674672 @default.
• W4387241754 hasRelatedWork W3002986063 @default.
• W4387241754 hasRelatedWork W3208090289 @default.
• W4387241754 hasRelatedWork W3210359220 @default.
• W4387241754 hasRelatedWork W4322705554 @default.
• W4387241754 isParatext "false" @default.
• W4387241754 isRetracted "false" @default.
• W4387241754 workType "article" @default.