Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387241856> ?p ?o ?g. }
- W4387241856 abstract "Red cabbage anthocyanins may provide health benefits that may be associated with antiaging. The protection of red cabbage anthocyanin-rich extract (ARE) and cyanidin-3-diglucoside-5-glucoside-rich extract (CY3D5G) against age-related cognitive dysfunction was investigated in normal aging mice (male C57BL/6J, 12 months old) administered orally for 12 weeks. Behavioral tests showed that ARE and CY3D5G significantly decreased cognitive impairment (p < 0.05) and had no effect on motor disorder. ARE and CY3D5G increased superoxide dismutase activity by 29.18 and 23.09% and decreased malondialdehyde by 15.74 and 10.05%, respectively, compared to the control. Histological staining showed that ARE and CY3D5G treatment reduced hippocampal neuronal damage and brain-derived neurotrophic factor degeneration. ARE and CY3D5G significantly reduced IL-1β and IL-6 levels in serum and brain (p < 0.05) by promoting the MAPK signaling pathway while enriching the abundance of butyrate-producing bacteria and altering the functional profile of the microbial community. In conclusion, ARE and CY3D5G may attenuate age-related cognitive dysfunction by reducing neuroinflammation and regulating the gut-brain axis." @default.
- W4387241856 created "2023-10-03" @default.
- W4387241856 creator A5068234681 @default.
- W4387241856 creator A5077026533 @default.
- W4387241856 date "2023-10-02" @default.
- W4387241856 modified "2023-10-03" @default.
- W4387241856 title "Red Cabbage Anthocyanins Attenuate Cognitive Impairment By Attenuating Neuroinflammation and Regulating Gut Microbiota in Aging Mice" @default.
- W4387241856 cites W1969570348 @default.
- W4387241856 cites W1973922157 @default.
- W4387241856 cites W1984230217 @default.
- W4387241856 cites W2055339187 @default.
- W4387241856 cites W2063954678 @default.
- W4387241856 cites W2084484561 @default.
- W4387241856 cites W2118424059 @default.
- W4387241856 cites W2158506678 @default.
- W4387241856 cites W2159409509 @default.
- W4387241856 cites W2169473035 @default.
- W4387241856 cites W2193546234 @default.
- W4387241856 cites W2622475329 @default.
- W4387241856 cites W2730094387 @default.
- W4387241856 cites W2736164782 @default.
- W4387241856 cites W2767505663 @default.
- W4387241856 cites W2768174197 @default.
- W4387241856 cites W2784799169 @default.
- W4387241856 cites W2884802815 @default.
- W4387241856 cites W2899367554 @default.
- W4387241856 cites W2902360588 @default.
- W4387241856 cites W2920485427 @default.
- W4387241856 cites W2964520550 @default.
- W4387241856 cites W2969326780 @default.
- W4387241856 cites W2988806944 @default.
- W4387241856 cites W2996654920 @default.
- W4387241856 cites W2996807786 @default.
- W4387241856 cites W2997802168 @default.
- W4387241856 cites W3004294166 @default.
- W4387241856 cites W3010989512 @default.
- W4387241856 cites W3015177924 @default.
- W4387241856 cites W3094846265 @default.
- W4387241856 cites W3110315448 @default.
- W4387241856 cites W3131675547 @default.
- W4387241856 cites W3149451154 @default.
- W4387241856 cites W3161020633 @default.
- W4387241856 cites W3175450721 @default.
- W4387241856 cites W3199976909 @default.
- W4387241856 cites W3202122504 @default.
- W4387241856 cites W4233545766 @default.
- W4387241856 cites W4319310534 @default.
- W4387241856 doi "https://doi.org/10.1021/acs.jafc.3c03183" @default.
- W4387241856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37781995" @default.
- W4387241856 hasPublicationYear "2023" @default.
- W4387241856 type Work @default.
- W4387241856 citedByCount "0" @default.
- W4387241856 crossrefType "journal-article" @default.
- W4387241856 hasAuthorship W4387241856A5068234681 @default.
- W4387241856 hasAuthorship W4387241856A5077026533 @default.
- W4387241856 hasConcept C126322002 @default.
- W4387241856 hasConcept C134018914 @default.
- W4387241856 hasConcept C148762608 @default.
- W4387241856 hasConcept C177857423 @default.
- W4387241856 hasConcept C203014093 @default.
- W4387241856 hasConcept C2775838275 @default.
- W4387241856 hasConcept C2776151105 @default.
- W4387241856 hasConcept C2776914184 @default.
- W4387241856 hasConcept C2778401633 @default.
- W4387241856 hasConcept C2779134260 @default.
- W4387241856 hasConcept C2779483572 @default.
- W4387241856 hasConcept C2984863031 @default.
- W4387241856 hasConcept C539455810 @default.
- W4387241856 hasConcept C71924100 @default.
- W4387241856 hasConcept C87753298 @default.
- W4387241856 hasConceptScore W4387241856C126322002 @default.
- W4387241856 hasConceptScore W4387241856C134018914 @default.
- W4387241856 hasConceptScore W4387241856C148762608 @default.
- W4387241856 hasConceptScore W4387241856C177857423 @default.
- W4387241856 hasConceptScore W4387241856C203014093 @default.
- W4387241856 hasConceptScore W4387241856C2775838275 @default.
- W4387241856 hasConceptScore W4387241856C2776151105 @default.
- W4387241856 hasConceptScore W4387241856C2776914184 @default.
- W4387241856 hasConceptScore W4387241856C2778401633 @default.
- W4387241856 hasConceptScore W4387241856C2779134260 @default.
- W4387241856 hasConceptScore W4387241856C2779483572 @default.
- W4387241856 hasConceptScore W4387241856C2984863031 @default.
- W4387241856 hasConceptScore W4387241856C539455810 @default.
- W4387241856 hasConceptScore W4387241856C71924100 @default.
- W4387241856 hasConceptScore W4387241856C87753298 @default.
- W4387241856 hasFunder F4320324202 @default.
- W4387241856 hasLocation W43872418561 @default.
- W4387241856 hasLocation W43872418562 @default.
- W4387241856 hasOpenAccess W4387241856 @default.
- W4387241856 hasPrimaryLocation W43872418561 @default.
- W4387241856 hasRelatedWork W1990447376 @default.
- W4387241856 hasRelatedWork W2041257525 @default.
- W4387241856 hasRelatedWork W2183540883 @default.
- W4387241856 hasRelatedWork W2509589047 @default.
- W4387241856 hasRelatedWork W3009493642 @default.
- W4387241856 hasRelatedWork W3119586409 @default.
- W4387241856 hasRelatedWork W4221067042 @default.
- W4387241856 hasRelatedWork W4281566553 @default.
- W4387241856 hasRelatedWork W4301701100 @default.
- W4387241856 hasRelatedWork W4303437387 @default.