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- W4387246487 abstract "The poor water solubility of traditional activatable organic molecular probes usually limits their detection ability in physiological environment. In this work, a positively charged H2S probe was designed, which exhibited a significantly enhanced responsiveness to H2S in the aggregated state due to the increased positive charge density on the aggregate surface. Under physiological conditions, the probe could be activated by H2S with specificity and sensitivity to release near-infrared fluorescence signal. Moreover, endogenous H2S levels in living cells were successfully monitored by using this probe. We expect that this probe can provide a new strategy for the design of activatable probes to break the limitation of poor water solubility of conventional organic molecular probes." @default.
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- W4387246487 date "2023-11-01" @default.
- W4387246487 modified "2023-10-15" @default.
- W4387246487 title "Specific imaging of intracellular hydrogen sulfide by a positively charged NIR fluorescent probe" @default.
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- W4387246487 doi "https://doi.org/10.1016/j.bmcl.2023.129495" @default.
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