FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387248321> ?p ?o ?g. }

• W4387248321 endingPage "A2957" @default.
• W4387248321 startingPage "A2956" @default.
• W4387248321 abstract "SESSION TITLE: Critical Care Case Report Posters 51 SESSION TYPE: Case Report Posters PRESENTED ON: 10/11/2023 12:00 pm - 12:45 pm INTRODUCTION: Mycobacterium Avium Complex (MAC) is an uncommonly encountered clinical pathogen found ubiquitously in the environment, including water and soil. It is an established cause of pulmonary infections, superficial lymphadenitis, and disseminated disease in immunocompromised hosts. However, it is exceedingly rare in an HIV-positive patient with a normal CD4 count, given that it is most commonly seen among patients with AIDS and a CD4 count <50 cells/microL. CASE PRESENTATION: We report a case of MAC bacteremia in a 34 years old female with a past medical history of hypertension, diabetes, and HIV, on highly active antiretroviral therapy (HAART), end-stage renal disease (ESRD) on hemodialysis. The patient visited the hospital every other day for her dialysis sessions. When she arrived, she complained of dizziness, weakness, fever, nausea, and vomiting for the past week. The patient was intermittently adherent to HAART therapy. On admission, vitals were significant for blood pressure of 103/69 mmHg, a temperature of 100.9 F, and respiratory rate of 20 beats per minute. Physical examination was benign. Initial Complete blood count showed Hb 11.1g/dl, WBC 8.8 k/ul, and platelets 121,000/µL. CT scan of the chest showed multiple pulmonary nodules. A blood culture was obtained, and we also ordered a CD4/CD3 count and viral load. The patient was started on Genvoya, and empirical microbial coverage was initiated with cefepime and diflucan pending blood culture results. CD4+ T-cell count was 491 cells/µL, and plasma HIV RNA was 136,000 copies/mL.The patient's fever continued to wax and wane, prompting repeat blood cultures at the time of fever spikes. Blood cultures grew MAC after 20 days. The days it took to get a culture report posed a diagnostic challenge. The patient was started on Ethambutol and Azithromycin and was transferred to ICU due to hypotension requiring vasopressor support. She had a pulseless electrical activity arrest due to ongoing septic shock. ROSC was obtained, but the patient required intubation for airway protection. Due to the patient's multiple comorbidities and poor prognosis, the family decided on hospice care, and the patient expired after a long battle with HIV and MAC bacteremia. DISCUSSION: Potentiating factors for MAC infection in HIV patients include a CD4 count below 50 cells/microL, HIV RNA levels >1000 copies/mL, ongoing viral replication despite ART, and previous or opportunistic infections. Our case is unique because the patient presented with a CD4 count of 491 cells/µL and the diagnosis of MAC bacteremia with a CD4 count greater than 50 cells/microL has not been reported commonly. CONCLUSIONS: Our goal in reporting this case is to highlight the importance that Although MAC is commonly seen in HIV-positive patients with a CD4 count of < 50cells /microL, it cannot be excluded in patients with normal CD4 count. Persistent fever with atypical symptoms not responding to empiric antibiotic therapy should prompt further evaluation for opportunistic infections, including MAC bacteremia. REFERENCE #1: Chaisson RE, Moore RD, Richman DD, et al. Incidence and natural history of Mycobacterium avium-complex infections in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group. Am Rev Respir Dis 1992; 146:285. REFERENCE #2: A Case of Isolated Pulmonary Mycobacterium Avium Complex Being the First Presentation of a Newly Diagnosed HIV/AIDSMonitoring Editor: Alexander Muacevic and John R AdlerFuad I Abaleka,corresponding author1 Bisrat Nigussie,1 Ozlem Onal,1 Rana Al-Zakhari,1 and Esmael Yimer1 REFERENCE #3: Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature Courtney Lane-Donovan, Emma Bainbridge, John Szumowski, Andrew D Kerkhoff, Michael J Peluso Author NotesOpen Forum Infectious Diseases, Volume 8, Issue 11, November 2021, ofab450, https://doi.org/10.1093/ofid/ofab450Published: 30 October 2021 DISCLOSURES: No relevant relationships by Song Peng Ang No relevant relationships by Wajahat Khan No relevant relationships by saria qaiser No relevant relationships by Cristina Rodriguez No relevant relationships by Carlos Valladares" @default.
• W4387248321 created "2023-10-03" @default.
• W4387248321 creator A5024263952 @default.
• W4387248321 creator A5063250645 @default.
• W4387248321 creator A5075456457 @default.
• W4387248321 creator A5077566174 @default.
• W4387248321 creator A5091633742 @default.
• W4387248321 date "2023-10-01" @default.
• W4387248321 modified "2023-10-03" @default.
• W4387248321 title "MYCOBACTERIUM AVIUM COMPLEX BACTEREMIA IN AN HIV POSITIVE PATIENT WITH NORMAL CD4 COUNT" @default.
• W4387248321 doi "https://doi.org/10.1016/j.chest.2023.07.1936" @default.
• W4387248321 hasPublicationYear "2023" @default.
• W4387248321 type Work @default.
• W4387248321 citedByCount "0" @default.
• W4387248321 crossrefType "journal-article" @default.
• W4387248321 hasAuthorship W4387248321A5024263952 @default.
• W4387248321 hasAuthorship W4387248321A5063250645 @default.
• W4387248321 hasAuthorship W4387248321A5075456457 @default.
• W4387248321 hasAuthorship W4387248321A5077566174 @default.
• W4387248321 hasAuthorship W4387248321A5091633742 @default.
• W4387248321 hasConcept C126322002 @default.
• W4387248321 hasConcept C141071460 @default.
• W4387248321 hasConcept C142724271 @default.
• W4387248321 hasConcept C187212893 @default.
• W4387248321 hasConcept C2776301714 @default.
• W4387248321 hasConcept C2776376844 @default.
• W4387248321 hasConcept C2776409635 @default.
• W4387248321 hasConcept C2776962512 @default.
• W4387248321 hasConcept C2778063415 @default.
• W4387248321 hasConcept C2779443120 @default.
• W4387248321 hasConcept C2779473907 @default.
• W4387248321 hasConcept C2780505380 @default.
• W4387248321 hasConcept C2780852908 @default.
• W4387248321 hasConcept C2781069245 @default.
• W4387248321 hasConcept C501593827 @default.
• W4387248321 hasConcept C71924100 @default.
• W4387248321 hasConcept C86803240 @default.
• W4387248321 hasConcept C89423630 @default.
• W4387248321 hasConceptScore W4387248321C126322002 @default.
• W4387248321 hasConceptScore W4387248321C141071460 @default.
• W4387248321 hasConceptScore W4387248321C142724271 @default.
• W4387248321 hasConceptScore W4387248321C187212893 @default.
• W4387248321 hasConceptScore W4387248321C2776301714 @default.
• W4387248321 hasConceptScore W4387248321C2776376844 @default.
• W4387248321 hasConceptScore W4387248321C2776409635 @default.
• W4387248321 hasConceptScore W4387248321C2776962512 @default.
• W4387248321 hasConceptScore W4387248321C2778063415 @default.
• W4387248321 hasConceptScore W4387248321C2779443120 @default.
• W4387248321 hasConceptScore W4387248321C2779473907 @default.
• W4387248321 hasConceptScore W4387248321C2780505380 @default.
• W4387248321 hasConceptScore W4387248321C2780852908 @default.
• W4387248321 hasConceptScore W4387248321C2781069245 @default.
• W4387248321 hasConceptScore W4387248321C501593827 @default.
• W4387248321 hasConceptScore W4387248321C71924100 @default.
• W4387248321 hasConceptScore W4387248321C86803240 @default.
• W4387248321 hasConceptScore W4387248321C89423630 @default.
• W4387248321 hasIssue "4" @default.
• W4387248321 hasLocation W43872483211 @default.
• W4387248321 hasOpenAccess W4387248321 @default.
• W4387248321 hasPrimaryLocation W43872483211 @default.
• W4387248321 hasRelatedWork W113810927 @default.
• W4387248321 hasRelatedWork W169120730 @default.
• W4387248321 hasRelatedWork W1717264974 @default.
• W4387248321 hasRelatedWork W1987520330 @default.
• W4387248321 hasRelatedWork W2003864032 @default.
• W4387248321 hasRelatedWork W2043522806 @default.
• W4387248321 hasRelatedWork W2054899674 @default.
• W4387248321 hasRelatedWork W2098587186 @default.
• W4387248321 hasRelatedWork W2151337835 @default.
• W4387248321 hasRelatedWork W2599676525 @default.
• W4387248321 hasVolume "164" @default.
• W4387248321 isParatext "false" @default.
• W4387248321 isRetracted "false" @default.
• W4387248321 workType "article" @default.