FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387249546> ?p ?o ?g. }

• W4387249546 endingPage "A1490" @default.
• W4387249546 startingPage "A1489" @default.
• W4387249546 abstract "SESSION TITLE: Chest Infections Case Report Posters 16 SESSION TYPE: Case Report Posters PRESENTED ON: 10/09/2023 02:10 pm - 02:55 pm INTRODUCTION: The dengue epidemic is a major health-related threat in India. A total of 110 million cases of Dengue were reported from January to October 2022, trends similar to those in 2018 [1]. Zoonotic infections have been on the rise, both globally and in India [2]. Other infections like Leptospira, zoonotic infections and scrub typhus are also common and present with overlapping symptoms. They can often present as co-infection, leading to missed diagnosis and lack of antibiotic therapy against all the causative organisms, thus affecting morbidity and mortality [3]. The physician should have a strong suspicion and make an early attempt to identify and treat the condition since most of the time these are featureless and treatable, but delaying treatment increases the risk of serious consequences such as encephalitis, Acute Respiratory Distress Syndrome(ARDS), and Multiorgan dysfunction syndrome(MODS). CASE PRESENTATION: A 25-year-old female was referred to our hospital to receive treatment for dengue and its complications. The initial workup was suggestive of high-grade fever, severe anaemia, transaminitis, Acute kidney injury and thrombocytopenia. On the first day of admission, she developed shortness of breath and the examination was suggestive of bilateral crepitus, USG of the Chest showed a left-sided minimal pleural effusion. The patient became oxygen dependent, and was deteriorating hemodynamically, and thus was shifted to the ICU. The patient with the above findings was treated as Multiorgan dysfunction Syndrome and was managed conservatively. The patient was subsequently intubated and diagnosed with ARDS. The fever persisted and the blood culture and dengue serology sent on the first day came out negative, followed by addition of Doxycycline for other zoonotic coverage. Scrub typhus IgG was sent and came back positive. This led to the diagnosis of secondary zoonotic infection by scrub typhus causing ARDS and MODS. DISCUSSION: Fever, chills, myalgia, and headaches are overlapping symptoms seen in all leptospira, dengue and scrub typhus. Leptospira has a longer incubation period of 2-30 days, while scrub typhus and dengue have a shorter of 5-10 days. Leptospira can additionally present with encephalitis and pulmonary and subconjunctival haemorrhages, and rarely ARDS. Scrub typhus has transaminitis acute kidney injury and ARDS more frequently than the rest, and is also associated with multiorgan failure. The clinical course of Scrub typhus is more rapid than Dengue. Sometimes fever may get resolved but transaminitis and AKI may persist which suggests a more likely zoonotic infection rather than dengue. Transaminitis and deranged renal function may persist even after complete clinical recovery [3]. CONCLUSIONS: Even during a dengue epidemic, a patient with thrombocytopenia, transaminitis, mildly deranged renal function tests and rapidly deteriorating is not the initial presentation of dengue in the absence of shock. For this presentation infectious agents like Scrub typhus, Rickettsiae and leptospira should also be ruled out. In case of an emergency and high clinical suspicion of a case especially from the endemic area, doxycycline should be started from the beginning to give early coverage against these zoonotic bugs. REFERENCE #1: National Center for Vector Borne Diseases Control Dengue/DHF situation in India: National Center for Vector Borne Diseases Control. https://nvbdcp.gov.in/index4.php?lang=1&level=0&linkid=431&lid=3715 REFERENCE #2: Kumar, Sanjiv, Swain, Sumant, S, Preetha G., Singh, B. S., and Divya Aggarwal. Zoonotic Diseases in India. Indian Journal of Community Medicine : Official Publication of Indian Association of Preventive & Social Medicine 45, no. Suppl 1 (2020): S1. Accessed March 31, 2023. https://doi.org/10.4103/ijcm.IJCM_360_19. REFERENCE #3: Serological Evidence of Co-infection of Dengue, Leptospirosis and Scrub Typhus in Patients Presenting with Acute Febrile Illness in a Tertiary care Hospital. European Journal of Molecular & Clinical Medicine, 2022; 9(3): 2009-2020. DISCLOSURES: No relevant relationships by Tanvi Grover No relevant relationships by Rohil Jain No relevant relationships by Y. Porwal No relevant relationships by Vagisha Sharma" @default.
• W4387249546 created "2023-10-03" @default.
• W4387249546 creator A5064006382 @default.
• W4387249546 creator A5064168585 @default.
• W4387249546 creator A5074735949 @default.
• W4387249546 creator A5089542345 @default.
• W4387249546 date "2023-10-01" @default.
• W4387249546 modified "2023-10-03" @default.
• W4387249546 title "IS IT DENGUE OR SOMETHING ELSE: A DIAGNOSTICIAN DILEMMA DURING THE DENGUE EPIDEMIC" @default.
• W4387249546 doi "https://doi.org/10.1016/j.chest.2023.07.1026" @default.
• W4387249546 hasPublicationYear "2023" @default.
• W4387249546 type Work @default.
• W4387249546 citedByCount "0" @default.
• W4387249546 crossrefType "journal-article" @default.
• W4387249546 hasAuthorship W4387249546A5064006382 @default.
• W4387249546 hasAuthorship W4387249546A5064168585 @default.
• W4387249546 hasAuthorship W4387249546A5074735949 @default.
• W4387249546 hasAuthorship W4387249546A5089542345 @default.
• W4387249546 hasConcept C126322002 @default.
• W4387249546 hasConcept C142724271 @default.
• W4387249546 hasConcept C177713679 @default.
• W4387249546 hasConcept C187212893 @default.
• W4387249546 hasConcept C203014093 @default.
• W4387249546 hasConcept C2776348555 @default.
• W4387249546 hasConcept C2777714996 @default.
• W4387249546 hasConcept C2777914695 @default.
• W4387249546 hasConcept C2778033228 @default.
• W4387249546 hasConcept C2779634585 @default.
• W4387249546 hasConcept C2780472472 @default.
• W4387249546 hasConcept C533803919 @default.
• W4387249546 hasConcept C71924100 @default.
• W4387249546 hasConceptScore W4387249546C126322002 @default.
• W4387249546 hasConceptScore W4387249546C142724271 @default.
• W4387249546 hasConceptScore W4387249546C177713679 @default.
• W4387249546 hasConceptScore W4387249546C187212893 @default.
• W4387249546 hasConceptScore W4387249546C203014093 @default.
• W4387249546 hasConceptScore W4387249546C2776348555 @default.
• W4387249546 hasConceptScore W4387249546C2777714996 @default.
• W4387249546 hasConceptScore W4387249546C2777914695 @default.
• W4387249546 hasConceptScore W4387249546C2778033228 @default.
• W4387249546 hasConceptScore W4387249546C2779634585 @default.
• W4387249546 hasConceptScore W4387249546C2780472472 @default.
• W4387249546 hasConceptScore W4387249546C533803919 @default.
• W4387249546 hasConceptScore W4387249546C71924100 @default.
• W4387249546 hasIssue "4" @default.
• W4387249546 hasLocation W43872495461 @default.
• W4387249546 hasOpenAccess W4387249546 @default.
• W4387249546 hasPrimaryLocation W43872495461 @default.
• W4387249546 hasRelatedWork W2000956038 @default.
• W4387249546 hasRelatedWork W2087006580 @default.
• W4387249546 hasRelatedWork W2131384146 @default.
• W4387249546 hasRelatedWork W2142347077 @default.
• W4387249546 hasRelatedWork W2895360593 @default.
• W4387249546 hasRelatedWork W2999859051 @default.
• W4387249546 hasRelatedWork W3034889157 @default.
• W4387249546 hasRelatedWork W4224214534 @default.
• W4387249546 hasRelatedWork W4244652115 @default.
• W4387249546 hasRelatedWork W4256211532 @default.
• W4387249546 hasVolume "164" @default.
• W4387249546 isParatext "false" @default.
• W4387249546 isRetracted "false" @default.
• W4387249546 workType "article" @default.