FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387249600> ?p ?o ?g. }

• W4387249600 endingPage "A794" @default.
• W4387249600 startingPage "A794" @default.
• W4387249600 abstract "SESSION TITLE: Chest Infections Posters 1 SESSION TYPE: Original Investigation Posters PRESENTED ON: 10/10/2023 12:00 pm - 12:45 pm PURPOSE: The novel coronavirus SARS-CoV-2, better known as COVID-19, has been shown to have major thromboembolic complications. Data supports pharmacologic thromboprophylaxis for all inpatients with COVID-19. The American Society of Hematology recommends against continued thromboembolic prophylaxis upon hospital discharge. However, the recent MICHELLE trial showed a significant reduction in post-discharge thrombotic events with extended use of anticoagulation in patients deemed high risk based a scoring system (accounting for active malignancy, known thrombophilic disorder or history of prior thromboembolic disease). The purpose of our study is to help identify hospitalized patients without known predisposing conditions who are at high risk of thromboembolic complications of COVID-19 post-discharge. METHODS: This is a single-center retrospective analysis of approximately 150 adult patients hospitalized with COVID-19 between August 1st, 2021 and August 1st, 2022. Study group is defined as having thromboembolic events within 60 days of testing positive for COVID-19. Control group is defined is patients who did not have thromboembolic complications. Patients with known malignancy, thrombophilic disorder, or prior VTE were excluded. Patient data includes C-reactive protein (CRP) and D-dimer levels, degree of hypoxia and/or need for ventilatory support and basic patient characteristics such as age and gender. Analysis was based on ANOVA with a P value of less than .05 to determine significance. RESULTS: Results showed a significant difference in D-dimers between COVID-19 infected patients with VTE compared to COVID-19 infected patients without VTE (P = .00531). No significant difference was noted in CRP levels (p = .536) between the two groups. PE was the most common diagnosis of VTE among COVID-19 infected patient and those who were readmitted. Interestingly, elevated CRP was associated with readmission for VTE (p = .03) while D-dimer was not associated with VTE readmission (p = .6). CONCLUSIONS: D-dimer is a good marker to determine risk of VTE patients with active COVID-19 infection. Certain characteristics such as elevated CRP seen in COVID-19 patients with thromboembolic disease may ultimately guide prophylaxis for thromboembolic disease upon discharge. CLINICAL IMPLICATIONS: Inflammatory markers such as D-dimer and CRP may help identify those patients who are at higher risk of developing thromboembolic complications of COVID-19 and who would benefit from continued prophylactic anticoagulation upon hospital discharge. DISCLOSURES: No relevant relationships by Aditya Agarwal No relevant relationships by Umbreen Ahmad No relevant relationships by Ayfer Ekiz" @default.
• W4387249600 created "2023-10-03" @default.
• W4387249600 creator A5058390016 @default.
• W4387249600 creator A5071612247 @default.
• W4387249600 creator A5036452721 @default.
• W4387249600 date "2023-10-01" @default.
• W4387249600 modified "2023-10-03" @default.
• W4387249600 title "THROMBOEMBOLIC COMPLICATIONS ASSOCIATED WITH COVID-19: A SINGLE-CENTER STUDY" @default.
• W4387249600 doi "https://doi.org/10.1016/j.chest.2023.07.590" @default.
• W4387249600 hasPublicationYear "2023" @default.
• W4387249600 type Work @default.
• W4387249600 citedByCount "0" @default.
• W4387249600 crossrefType "journal-article" @default.
• W4387249600 hasAuthorship W4387249600A5036452721 @default.
• W4387249600 hasAuthorship W4387249600A5058390016 @default.
• W4387249600 hasAuthorship W4387249600A5071612247 @default.
• W4387249600 hasBestOaLocation W43872496001 @default.
• W4387249600 hasConcept C126322002 @default.
• W4387249600 hasConcept C167135981 @default.
• W4387249600 hasConcept C2779134260 @default.
• W4387249600 hasConcept C2779399171 @default.
• W4387249600 hasConcept C2780073493 @default.
• W4387249600 hasConcept C2780868729 @default.
• W4387249600 hasConcept C3008058167 @default.
• W4387249600 hasConcept C524204448 @default.
• W4387249600 hasConcept C71924100 @default.
• W4387249600 hasConceptScore W4387249600C126322002 @default.
• W4387249600 hasConceptScore W4387249600C167135981 @default.
• W4387249600 hasConceptScore W4387249600C2779134260 @default.
• W4387249600 hasConceptScore W4387249600C2779399171 @default.
• W4387249600 hasConceptScore W4387249600C2780073493 @default.
• W4387249600 hasConceptScore W4387249600C2780868729 @default.
• W4387249600 hasConceptScore W4387249600C3008058167 @default.
• W4387249600 hasConceptScore W4387249600C524204448 @default.
• W4387249600 hasConceptScore W4387249600C71924100 @default.
• W4387249600 hasIssue "4" @default.
• W4387249600 hasLocation W43872496001 @default.
• W4387249600 hasOpenAccess W4387249600 @default.
• W4387249600 hasPrimaryLocation W43872496001 @default.
• W4387249600 hasRelatedWork W2022520514 @default.
• W4387249600 hasRelatedWork W2085148854 @default.
• W4387249600 hasRelatedWork W2335157939 @default.
• W4387249600 hasRelatedWork W2999710862 @default.
• W4387249600 hasRelatedWork W3018641166 @default.
• W4387249600 hasRelatedWork W3090707124 @default.
• W4387249600 hasRelatedWork W3127174492 @default.
• W4387249600 hasRelatedWork W3210359220 @default.
• W4387249600 hasRelatedWork W334600261 @default.
• W4387249600 hasRelatedWork W1603374058 @default.
• W4387249600 hasVolume "164" @default.
• W4387249600 isParatext "false" @default.
• W4387249600 isRetracted "false" @default.
• W4387249600 workType "article" @default.