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• W4387249802 abstract "SESSION TITLE: Cardiovascular Disease Case Report Posters 21 SESSION TYPE: Case Report Posters PRESENTED ON: 10/09/2023 02:10 pm - 02:55 pm INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) and coronavirus disease (COVID-19) predominantly causes respiratory symptoms. Although rare, cardiac complications from COVID-19 have been documented. Here we present a case of acute viral pericarditis complicated by cardiac tamponade due to COVID-19. CASE PRESENTATION: A 56-year-old female presented with an episode of presyncope. The patient tested positive for COVID-19 at the time of admission. Initial workup included electrocardiogram which showed sinus tachycardia with low voltage QRS in both precordial and limb leads. Transthoracic echocardiogram showed a large pericardial effusion with chamber collapse of the right atrium and ventricle suggestive of tamponade physiology. A pericardiocentesis was performed and 100 mL of serous pericardial fluid was drained. Work up for bacterial, fungal, and rheumatologic etiologies as cause were negative. Reverse transcriptase polymerase chain reaction (RT-PCR) testing for SARS-Cov-2 in the pericardial fluid was negative as well. Cytopathology of pericardial fluid was negative for any evidence of malignancy. The patient was treated with high dose non-steroidal anti-inflammatory medications along with Colchicine for acute viral pericarditis. The patient's clinical picture improved, as she was discharged soon thereafter. DISCUSSION: Cases of acute viral pericarditis complicated by cardiac tamponade associated with COVID-19 infection have been rarely reported in the literature. The proposed mechanism of action is through an inflammatory response caused by the viral illness. Myocardial inflammation and the release of pro-inflammatory cytokines may lead to capillary leakage, which causes the development of the pericardial effusion. This mechanism is supported as result of RT-PCR testing of pericardial fluid for SARS-Cov-2 was negative, implying no direct invasion of the myocardium or pericardium is cause for this clinical picture. CONCLUSIONS: COVID-19 is an illness which causes pulmonary manifestations. Although rare, cardiac complications may arise from this infection. Pericarditis associated with cardiac tamponade is a severe complication from this condition and should be considered in patients with COVID-19. REFERENCE #1: Dweck MR, Bularga A, Hahn RT, et al. Global evaluation of echocardiographyin patients with COVID-19. Eur Heart J Cardiovasc Imaging.2020;21(9):949–958. REFERENCE #2: Fox K, Prokup JA, Butson K, Jordan K. Acute effusive pericarditis: alate complication of COVID-19. Cureus. 2020;12(7):e9074. REFERENCE #3: Huang C, Wang Y, Li X, et al.: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020, 395:497-506. 10.1016/S0140-6736(20)30183-5 DISCLOSURES: No relevant relationships by Harish Gidda No relevant relationships by Inderpal Singh No relevant relationships by Jordan Swisher" @default.
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• W4387249802 date "2023-10-01" @default.
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• W4387249802 title "ACUTE VIRAL PERICARDITIS COMPLICATED BY CARDIAC TAMPONADE AS A RESULT OF COVID-19" @default.
• W4387249802 doi "https://doi.org/10.1016/j.chest.2023.07.343" @default.
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