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• W4387253159 abstract "SESSION TITLE: Education, Research, and Quality Improvement Posters 6 SESSION TYPE: Original Investigation Posters PRESENTED ON: 10/11/2023 12:00 pm - 12:45 pm PURPOSE: A clot lodged in the vasculature of the pulmonary system is one of the most fear complications in the hospital. If left untreated, a pulmonary embolism is associated with an overall mortality of up to 30%. Over 300,000 patients a year are diagnosed with pulmonary embolisms in the United States. This has led to the creation of multidisciplinary Pulmonary Embolism Response Teams (PERT), first pioneered at Mass General Hospital in 2014. While there is no singular prescribed PERT composition, the commonly incorporated members include pulmonology/critical care, cardiology, emergency medicine, hematology, surgery, and radiology departments. Once activated, the team can review the pertinent information to deliver efficient, evidence-based care. Although its effectiveness is controversial, it is speculated that PERTs improve efficiency by streamlining potential consultations and facilitating access to advanced therapies, thereby improving clinical outcomes. This study aims to evaluate the outcome of PERT team implementation in the United States through a meta-analysis of the current literature. METHODS: The authors searched PubMed for literature comparing patient outcomes with and without Pulmonary Embolisms Response Teams (PERT) in the United States from February 2018 to February 2023. A total of 22 studies were first identified. Studies were further stratified by whether they reported mortality data resulting in a total inclusion of 10 studies. We then conducted a meta-analysis to determine if there was statistical significance in these clinical outcomes. RESULTS: The integration of PERT teams resulted in an overall reduction in mortality (8.79% vs. 10.88% [Risk Ratio 0.97 (95% CI 0.95-0.99), fixed effects model; p=0.01]). 3 out of 10 studies showed a reduced risk of mortality, 6 out of 10 showed no significant difference and 1 out of 10 reported an increased risk of mortality with the implementation of PERT teams. Subgroup analysis revealed that studies incorporating imaging as a primary metric for inclusion were statistically more likely to report positive results (66.70% vs 42.90%; p=0.021, chi-squared). CONCLUSIONS: The implementation of PERT teams reduces patient mortality. Secondly, the requirements of strict inclusion and exclusion criteria that specifically require imaging as a definitive diagnosis for PE are necessary to accurately evaluate the effectiveness of an intervention. CLINICAL IMPLICATIONS: Institutions may see a decrease in PE mortality by implementing PERT. PERTs can mobilize a multidisciplinary group of physicians with expertise in the diagnosis and management of acute pulmonary embolism to improve patient care. There is a wide range of treatment modalities such as anticoagulation, systemic thrombolysis, catheter-directed fibrinolysis, percutaneous thrombectomy, and surgical embolectomy. To further complicate matters, the heterogeneous nature of pulmonary embolism requires multi-specialty input, which can be a time-consuming proposition and logistically challenging. PERT can streamline this process and help determine the best treatment option in the management of pulmonary embolism. DISCLOSURES: No relevant relationships by Ladonya Jackson-Cowan No relevant relationships by Ummar Jamal No relevant relationships by Vinod Jeyaretnam No relevant relationships by Kevin Moriles No relevant relationships by Madeline Wetterhall" @default.
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• W4387253159 date "2023-10-01" @default.
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• W4387253159 title "PULMONARY EMBOLISM RESPONSE TEAMS (PERT) DECREASE MORTALITY IN THE US: A META-ANALYSIS" @default.
• W4387253159 doi "https://doi.org/10.1016/j.chest.2023.07.2462" @default.
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