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- W4387260250 abstract "This paper documents the first reported cases of patients in the Philippines in 2019 who underwent transvaginal ultrasound-guided trucut biopsy. Different indications for trucut biopsy were demonstrated, highlighting its clinical utility in the diagnosis and management of malignant pelvic tumours. The first case was in a 57 yo G0, s/p THBSO for an unknown pelvic tumour, presenting with abdominal enlargement. Ultrasound showed a 10 × 9 × 9 cm solid pelvic mass with moderate flow. Trucut biopsy was done which showed a poorly differentiated carcinoma with clear cell features. Immunohistochemistry (IHC) favoured a Müllerian origin, ruling out an adenocarcinoma of colonic origin. She subsequently underwent chemotherapy with carboplatin and paclitaxel. The second was in 54 yo G2P2, diagnosed with high-grade serous papillary carcinoma, ovary, stage IIIC, with persistent progressive disease who developed chemotherapy resistance. She was referred for trucut biopsy to obtain tissues for estrogen and progesterone receptor (ER/PR) to check if the tumour will be responsive to hormonal therapy. Ultrasound showed a 9 × 8 × 6 cm solid cul-de-sac mass with moderate flow. Trucut biopsy showed a metastatic ovarian high-grade serous adenocarcinoma strongly positive for ER and PR. She was subsequently started on tamoxifen therapy. The third was in a 66 yo G4P4 with abdominal enlargement and vaginal bleeding. Ultrasound showed a 22 × 23 × 18 cm solid abdominopelvic mass with minimal flow, with peritoneal carcinomatosis. Due to advanced disease and co-morbidties, the patient had trucut biopsy which showed a high-grade serous carcinoma with IHC consistent with a carcinosarcoma. She was eventually started on carboplatin and paclitaxel. Adequate samples were obtained from all patients with no procedure-related complications. The 3 cases presented have shown that trucut biopsy can be a safe and viable alternative to more invasive means of biopsy, with high diagnostic accuracy and adequacy." @default.
- W4387260250 created "2023-10-03" @default.
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- W4387260250 date "2023-10-01" @default.
- W4387260250 modified "2023-10-18" @default.
- W4387260250 title "EP29.21: Ultrasound‐guided trucut biopsy of pelvic tumours: first reported case series in the Philippines" @default.
- W4387260250 doi "https://doi.org/10.1002/uog.27184" @default.
- W4387260250 hasPublicationYear "2023" @default.
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