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- W4387260410 abstract "To evaluate maternal and perinatal outcomes of removal versus retention of cervical cerclage after PPROM. Medline, Embase and Cochrane databases were searched electronically on February 2023 utilising combinations of the relevant MeSH terms, keywords, and word variants that were considered suitable for the topic. Either prospective or retrospective trials were considered suitable for the inclusion. The coprimary outcome of this study were pregnancy latency > 7 days from PPROM and pregnancy latency > 48 hrs from PPROM. Random effect head-to-head meta-analyses were performed to compare each outcome, expressing the results as summary OR for dichotomous and as MD for continuous outcomes, plus relative 95% CI. Six studies involving a total of 377 women (169 vs 208) were included. The rate of pregnancy prolongation > 48 hrs was significantly lower in the removal compared to retention group (OR 0.15, 95% CI 0.07-0.31), as well as the rate of pregnancy prolongation > 7 days (OR 0.30 95% CI 0.11-0.83) and pregnancy latency expressed in days (MD -2.84 days, 95% CI -5.40 to -0.29). The rate of chorioamnionitis was significantly lower in the removal compared to the retention group (OR 0.57 95% CI 0.34-0.96) as was the rate of Apgar score < 7 at 5 minutes (OR 0.22 95% CI 0.08-0.56). There was no difference between removal and retention groups for all the other maternal and perinatal outcomes. The decision whether to remove or retain cerclage in case of PPROM should balance the prematurity-related risks with those of infectious complications, thus highlighting the need for a tailored management mainly based on gestational age at occurrence of PPROM. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W4387260410 date "2023-10-01" @default.
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- W4387260410 title "OP13.06: Removal versus retention of cervical cerclage with preterm prelabour rupture of membranes: systematic review and meta‐analysis" @default.
- W4387260410 doi "https://doi.org/10.1002/uog.26555" @default.
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