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- W4387260658 abstract "We aimed to evaluate the incidence and causes of perinatal death in patients with a prenatal diagnosis of vasa previa (VP). We conducted a systematic search of PubMed, Scopus, Web of Science, and Embase databases from 1 January 1987 to 1 January 2023. We included all cases of prenatally diagnosed VP. We identified all cases of perinatal death and in those cases ascertained the causes of death. Perinatal mortality data from cohort studies were pooled using the programming language software R (version 4.2.2) and analysed by the fixed-effects model after logit-transformation. A total of 113 studies were included, comprising 25 cohort studies with 1167 pregnancies and 88 case series/reports with 130 pregnancies. Thirteen perinatal deaths were reported, of which six were directly attributable to VP. Three of these deaths occurred in twin pregnancies, and two of them had a short cervix. In only two patients did perinatal death occur without any risk factors. The meta-analysis of cohort studies revealed an overall perinatal mortality rate of 0.94% (95% CI: 0.52-1.70, I2 = 0.0%), while the pooled perinatal mortality attributable to VP was 0.51% (95% CI: 0.23-1.14, I2 = 0.0%). Our findings suggest that the perinatal mortality in prenatally diagnosed VP is low and typically associated with known risk factors. Prenatal diagnosis of VP can have a significant psychological burden on patients due to the fear of perinatal death. It is crucial for pregnant individuals and healthcare teams to be aware of this low risk, which could alleviate the stress of families and enable physicians to provide more evidence-based counselling and management." @default.
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- W4387260658 date "2023-10-01" @default.
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- W4387260658 title "OP08.09: Causes of death and perinatal mortality rate in patients with prenatally diagnosed vasa previa: a systematic review and meta‐analysis" @default.
- W4387260658 doi "https://doi.org/10.1002/uog.26518" @default.
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