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- W4387263416 abstract "Syn: truncus arteriosus, truncus arteriosus communis, aorticopulmonary trunk. Common arterial trunk is a conotruncal malformation, where a single outflow tract arises from the heart and leads to the systemic, coronary, and pulmonary circulations. Basic embryologic defect: Two embryologic processes are needed for the normal development of the outflow tract: elongation and repositioning of the primitive conotruncus from over the right ventricle to over the ventricular septum, and septation of the conotruncus followed by rotation, resulting in a right-sided pulmonary artery, arising from the RV, and a left-sided aorta, arising from the left ventricle – failure of septation results in CAT. A ventricular septal defect is always present due to deficient conal septum. Anomaly scan in 23yr F primigravida revealed 21-22w gestation with following findings – 4Ch view: extreme LAD of 107.85 degree; 5Ch view: outlet VSD, single overriding great vessel (aorta as CAT) with thickened dysplastic valves and mild truncal regurgitation on spectral Doppler; 3VT view: left aortic arch as enlarged single great vessel (aorta), narrow MPA with its bifurcation arising from aorta at a level below and behind sternal end of right clavicle, extreme thymic hypoplasia, absent ductus arteriosus; Arch view: single aortic (truncal) arch. CAT is classified into four types based on the anatomic origin of the pulmonary arteries. The two most common prenatally encountered types are type 1/type A1 and type A4. Our case is type 1/type A1. The persistence of the CAT corresponds to a very early interruption of the mechanism of rotation and the septation of the outflow tract and absence of development of the outlet septum (outlet VSD)." @default.
- W4387263416 created "2023-10-03" @default.
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- W4387263416 date "2023-10-01" @default.
- W4387263416 modified "2023-10-03" @default.
- W4387263416 title "EP24.45: Common arterial trunk type 1 (by Collett and Edwards) – type A1 (by Van Praagh and Van Praagh) at 22 weeks" @default.
- W4387263416 doi "https://doi.org/10.1002/uog.27093" @default.
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