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- W4387263670 abstract "Tubal patency assessment is an important part of routine infertility work-up. It has been suggested that hysterosalpingography should no longer be considered as a ‘first line’ diagnostic procedure. We aim to determine the accuracy of an alternative technique, hysterosalpingo-foam-sonography (HyFoSy), in tubal patency assessment in infertile women. This prospective study was conducted at My Duc Hospital and was approved by the institutional ethics committee (25/2019/MD). Infertile women aged >18 years, who were scheduled for undergoing laparoscopy during infertility investigation. Two experienced sonographers were involved in HyFoSy. A visual analogue scale (VAS) score for perception of pain during HyFoSy was used. Laparoscopy with dye chromotubation, was performed on the same day and was used as a gold standard. Clinicians performing laparoscopy were blinded to HyFoSy results. Sensitivity, specificity, negative and positive predictive value (NPV, PPV) and 95% confidence interval (CI) were calculated. A sample size of 455 women (910 tubes) was needed to demonstrate a non-exceeding 8% of fluctuation hypothesis of the two sensitivity and specificity (power 0.80, two-sided alpha 5%, loss to follow-up 5%). Between Dec-2019 and Dec-2022, there were 455 women recruited. Four women had inconclusive HyFoSy results and three women withdrew their consents. Data analysis was performed on the remaining 488 women (868 fallopian tubes). The sensitivity and specificity of HyFoSy, as compared to laparoscopy, were 0.76 (95% CI 0.72–0.80) and 0.71 (95% CI 0.67–0.75), respectively. HyFoSy gave a PPV of 0.72 (95% CI 0.69-0.76) and a NPV of 0.75 (95% CI 0.72-0.78). 50% of women reported a VAS score of no pain. No adverse event was reported. HyFoSy is well-tolerated, safe, and reliable technique compared to laparoscopy for tubal patency assessment." @default.
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- W4387263670 date "2023-10-01" @default.
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- W4387263670 title "EP33.08: Diagnostic accuracy of hysterosalpingo‐foam‐sonography for fallopian tube patency assessment in infertile women" @default.
- W4387263670 doi "https://doi.org/10.1002/uog.27238" @default.
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