Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387264301> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4387264301 endingPage "52" @default.
- W4387264301 startingPage "46" @default.
- W4387264301 abstract "Background: Laparoscopic cholecystectomy is a commonly performed surgery and stable intraoperative hemodynamic status is desirable during pneumoperitonium. Clonidine and dexmedetomidine (alpha-2 adrenergic agonist) were used in this study to attenuate the stress response of pneumoperitoneum because alpha-2 adrenergic agonists help in the attenuation of neuroendocrine and hemodynamic responses to surgery and anesthesia, due to its sympatholytic action. Aims and Objectives: The aims and objectives of the study are to conduct a comparative evaluation of clonidine and dexmedetomidine as pre-anesthetic medication for the attenuation of hemodynamic changes during laparoscopic cholecystectomy surgeries. Materials and Methods: Eighty patients of either sex, aged 20–50 years, complying to the American Society of Anesthesiologists physical status I-II, scheduled for elective laparoscopic cholecystectomy under general anesthesia were divided into two equal groups to receive either clonidine 1 mg/kg (Group-C, n=40) or dexmedetomidine 1 mg/kg (Group-D, n=40), both injected through intravenous route as 15 mL volume with normal saline. Heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, and SpO2 were measured before and after giving the study drugs, before and immediately after pneumoperitoneum, and then, at 10, 20, 30, 40, and 50 min of pneumoperitoneum. Results: Statistically significant difference was observed in heart rate in the dexmedetomidine group constantly since giving study drug, immediately after the creation of pneumoperitoneum, and then, 10, 20, 30, 40, and 50 min after pneumoperitoneum. Systolic, diastolic, and mean blood pressures were found to be significantly lower in Group D (except after administering study drug), immediately after creating pneumoperitoneum, and 10, 20, 30, 40, and 50 min after pneumoperitoneum. Conclusion: Dexmedetomidine as pre-medication is more efficacious in attenuating hemodynamic stress responses in laparoscopic cholecystectomy surgeries compared to clonidine as pre-medication." @default.
- W4387264301 created "2023-10-03" @default.
- W4387264301 creator A5000656764 @default.
- W4387264301 creator A5000827419 @default.
- W4387264301 creator A5023146827 @default.
- W4387264301 creator A5030231648 @default.
- W4387264301 creator A5047648144 @default.
- W4387264301 creator A5007937848 @default.
- W4387264301 date "2023-10-02" @default.
- W4387264301 modified "2023-10-03" @default.
- W4387264301 title "Comparison of efficacy between intravenous clonidine and dexmedetomidine as pre-medication in attenuating hemodynamic stress responses during laparoscopic cholecystectomy" @default.
- W4387264301 doi "https://doi.org/10.3126/ajms.v14i10.56463" @default.
- W4387264301 hasPublicationYear "2023" @default.
- W4387264301 type Work @default.
- W4387264301 citedByCount "0" @default.
- W4387264301 crossrefType "journal-article" @default.
- W4387264301 hasAuthorship W4387264301A5000656764 @default.
- W4387264301 hasAuthorship W4387264301A5000827419 @default.
- W4387264301 hasAuthorship W4387264301A5007937848 @default.
- W4387264301 hasAuthorship W4387264301A5023146827 @default.
- W4387264301 hasAuthorship W4387264301A5030231648 @default.
- W4387264301 hasAuthorship W4387264301A5047648144 @default.
- W4387264301 hasBestOaLocation W43872643011 @default.
- W4387264301 hasConcept C126322002 @default.
- W4387264301 hasConcept C141071460 @default.
- W4387264301 hasConcept C178853913 @default.
- W4387264301 hasConcept C2776452961 @default.
- W4387264301 hasConcept C2776814716 @default.
- W4387264301 hasConcept C2777953023 @default.
- W4387264301 hasConcept C2778399450 @default.
- W4387264301 hasConcept C2778746874 @default.
- W4387264301 hasConcept C2780047204 @default.
- W4387264301 hasConcept C2781302539 @default.
- W4387264301 hasConcept C42219234 @default.
- W4387264301 hasConcept C71924100 @default.
- W4387264301 hasConcept C84393581 @default.
- W4387264301 hasConceptScore W4387264301C126322002 @default.
- W4387264301 hasConceptScore W4387264301C141071460 @default.
- W4387264301 hasConceptScore W4387264301C178853913 @default.
- W4387264301 hasConceptScore W4387264301C2776452961 @default.
- W4387264301 hasConceptScore W4387264301C2776814716 @default.
- W4387264301 hasConceptScore W4387264301C2777953023 @default.
- W4387264301 hasConceptScore W4387264301C2778399450 @default.
- W4387264301 hasConceptScore W4387264301C2778746874 @default.
- W4387264301 hasConceptScore W4387264301C2780047204 @default.
- W4387264301 hasConceptScore W4387264301C2781302539 @default.
- W4387264301 hasConceptScore W4387264301C42219234 @default.
- W4387264301 hasConceptScore W4387264301C71924100 @default.
- W4387264301 hasConceptScore W4387264301C84393581 @default.
- W4387264301 hasIssue "10" @default.
- W4387264301 hasLocation W43872643011 @default.
- W4387264301 hasOpenAccess W4387264301 @default.
- W4387264301 hasPrimaryLocation W43872643011 @default.
- W4387264301 hasRelatedWork W2081710265 @default.
- W4387264301 hasRelatedWork W2766175412 @default.
- W4387264301 hasRelatedWork W2885960408 @default.
- W4387264301 hasRelatedWork W2907201553 @default.
- W4387264301 hasRelatedWork W2945603110 @default.
- W4387264301 hasRelatedWork W3173241491 @default.
- W4387264301 hasRelatedWork W915877265 @default.
- W4387264301 hasRelatedWork W2181944283 @default.
- W4387264301 hasRelatedWork W2592915238 @default.
- W4387264301 hasRelatedWork W3082641231 @default.
- W4387264301 hasVolume "14" @default.
- W4387264301 isParatext "false" @default.
- W4387264301 isRetracted "false" @default.
- W4387264301 workType "article" @default.