FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387266869> ?p ?o ?g. }

• W4387266869 endingPage "103585" @default.
• W4387266869 startingPage "103585" @default.
• W4387266869 abstract "Pegfilgrastim is a widely used long-acting granulocyte colony-stimulating factor (G-CSF) that prevents febrile neutropenia (FN) in patients with breast cancer receiving chemotherapy. This study aimed to evaluate the incidence of chemotherapy-related FN events and other adverse events (AEs) during chemotherapy in Korean patients with breast cancer treated with pegfilgrastim as secondary prophylactic support.This was a multicenter, open-label, prospective, observational study. A total of 1255 patients were enrolled from 43 institutions. The incidence of FN was evaluated as the primary endpoint. The secondary endpoints included (1) incidence of bone pain, (2) proportion of patients with a relative dose intensity (RDI) of ≥85%, and (3) proportion of patients with AE.Pegfilgrastim administration reduced FN by 11.8-1.6%. The highest incidence of bone pain was observed at the time point of the 1st day after the administration and mild bone pain was the most common of all bone pain severity. The mean RDI was 98.5 ± 7.3%, and the proportion of the patients with and RDI≥85% was 96.9% (1169/1233). AEs were reported in 52.6% of the patients, and serious drug reactions occurred in only 0.7%.The use of pegfilgrastim as secondary prophylaxis was effective and safe for preventing FN in patients with breast cancer who were treated with chemotherapy." @default.
• W4387266869 created "2023-10-03" @default.
• W4387266869 creator A5002152070 @default.
• W4387266869 creator A5003149946 @default.
• W4387266869 creator A5016420594 @default.
• W4387266869 creator A5020488538 @default.
• W4387266869 creator A5020511894 @default.
• W4387266869 creator A5027370880 @default.
• W4387266869 creator A5030173612 @default.
• W4387266869 creator A5041704574 @default.
• W4387266869 creator A5042471939 @default.
• W4387266869 creator A5046786802 @default.
• W4387266869 creator A5054043580 @default.
• W4387266869 creator A5057493764 @default.
• W4387266869 creator A5059686120 @default.
• W4387266869 creator A5060794553 @default.
• W4387266869 creator A5062491053 @default.
• W4387266869 creator A5063958673 @default.
• W4387266869 creator A5068156333 @default.
• W4387266869 creator A5078325682 @default.
• W4387266869 creator A5080971781 @default.
• W4387266869 creator A5081798094 @default.
• W4387266869 creator A5081996725 @default.
• W4387266869 creator A5082528697 @default.
• W4387266869 creator A5082551404 @default.
• W4387266869 creator A5082652221 @default.
• W4387266869 creator A5086982168 @default.
• W4387266869 creator A5087538009 @default.
• W4387266869 creator A5087610358 @default.
• W4387266869 creator A5088046066 @default.
• W4387266869 creator A5089068543 @default.
• W4387266869 date "2023-12-01" @default.
• W4387266869 modified "2023-10-15" @default.
• W4387266869 title "An observational, prospective, open label, multicenter study to evaluate the safety and effectiveness of pegfilgrastim as secondary prophylaxis to decrease the incidence of febrile neutropenia in Korean female patients with breast cancer" @default.
• W4387266869 cites W1957937187 @default.
• W4387266869 cites W1972469059 @default.
• W4387266869 cites W1989085210 @default.
• W4387266869 cites W2000487326 @default.
• W4387266869 cites W2005514220 @default.
• W4387266869 cites W2024933507 @default.
• W4387266869 cites W2036450045 @default.
• W4387266869 cites W2050887885 @default.
• W4387266869 cites W2058875082 @default.
• W4387266869 cites W2076143652 @default.
• W4387266869 cites W2083336892 @default.
• W4387266869 cites W2096104385 @default.
• W4387266869 cites W2097001782 @default.
• W4387266869 cites W2104029536 @default.
• W4387266869 cites W2115170812 @default.
• W4387266869 cites W2142195688 @default.
• W4387266869 cites W2316501895 @default.
• W4387266869 cites W2607332890 @default.
• W4387266869 cites W2801809723 @default.
• W4387266869 cites W3003670850 @default.
• W4387266869 cites W3017096042 @default.
• W4387266869 cites W3029874704 @default.
• W4387266869 cites W3047211276 @default.
• W4387266869 cites W3048696092 @default.
• W4387266869 cites W3087850776 @default.
• W4387266869 cites W3132411019 @default.
• W4387266869 cites W4200308211 @default.
• W4387266869 cites W4200492316 @default.
• W4387266869 cites W4213154982 @default.
• W4387266869 cites W4229333371 @default.
• W4387266869 doi "https://doi.org/10.1016/j.breast.2023.103585" @default.
• W4387266869 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37802015" @default.
• W4387266869 hasPublicationYear "2023" @default.
• W4387266869 type Work @default.
• W4387266869 citedByCount "0" @default.
• W4387266869 crossrefType "journal-article" @default.
• W4387266869 hasAuthorship W4387266869A5002152070 @default.
• W4387266869 hasAuthorship W4387266869A5003149946 @default.
• W4387266869 hasAuthorship W4387266869A5016420594 @default.
• W4387266869 hasAuthorship W4387266869A5020488538 @default.
• W4387266869 hasAuthorship W4387266869A5020511894 @default.
• W4387266869 hasAuthorship W4387266869A5027370880 @default.
• W4387266869 hasAuthorship W4387266869A5030173612 @default.
• W4387266869 hasAuthorship W4387266869A5041704574 @default.
• W4387266869 hasAuthorship W4387266869A5042471939 @default.
• W4387266869 hasAuthorship W4387266869A5046786802 @default.
• W4387266869 hasAuthorship W4387266869A5054043580 @default.
• W4387266869 hasAuthorship W4387266869A5057493764 @default.
• W4387266869 hasAuthorship W4387266869A5059686120 @default.
• W4387266869 hasAuthorship W4387266869A5060794553 @default.
• W4387266869 hasAuthorship W4387266869A5062491053 @default.
• W4387266869 hasAuthorship W4387266869A5063958673 @default.
• W4387266869 hasAuthorship W4387266869A5068156333 @default.
• W4387266869 hasAuthorship W4387266869A5078325682 @default.
• W4387266869 hasAuthorship W4387266869A5080971781 @default.
• W4387266869 hasAuthorship W4387266869A5081798094 @default.
• W4387266869 hasAuthorship W4387266869A5081996725 @default.
• W4387266869 hasAuthorship W4387266869A5082528697 @default.
• W4387266869 hasAuthorship W4387266869A5082551404 @default.
• W4387266869 hasAuthorship W4387266869A5082652221 @default.
• W4387266869 hasAuthorship W4387266869A5086982168 @default.
• W4387266869 hasAuthorship W4387266869A5087538009 @default.
• W4387266869 hasAuthorship W4387266869A5087610358 @default.
• W4387266869 hasAuthorship W4387266869A5088046066 @default.

• next