FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387296291> ?p ?o ?g. }

• W4387296291 abstract "Foodborne Salmonella infection remains a major public health concern worldwide. With rising antimicrobial resistance, genomic surveillance is key to tracking outbreaks and monitoring transmission, but there is no comprehensive national surveillance scheme for Salmonella involving humans, food, animals, and the environment in China. Moreover, the association between antimicrobial resistance and climate, social, and economic factors has rarely been investigated. Here, we use 1,962 Salmonella isolates collected from 22 Chinese provinces and add 6,035 publicly available genomes to build a Chinese local Salmonella genome database version 2 (CLSGDB v2) representing 30 Chinese provinces, covering 1905-2022. Using the CLSGDB v2, we mapped the landscape and spatiotemporal dynamics of antimicrobial resistance markers, virulome, and mobilome in Salmonella. We identified 317 mcr positive and 745 azithromycin resistance genes positive Salmonella isolates out of 7,997 isolates. We further uncovered the geographic distribution veil of mcr-1, fosA7, fosA3, mph(A), and blaCTX-M-55 genes in China, all of them resistant to the critically important antimicrobials including colistin, fosfomycin, azithromycin, and the third-generation cephalosporins. Interestingly, economic, climatic, and social factors can drive the rise of antimicrobial resistance was observed. Finally, we release the CLSGDB v2 as an open-access database and thus can assist surveillance studies tracking 164 Salmonella enterica serovars and 295 sequence types across the globe. The CLSGDB v2 is freely available at https://nmdc.cn/clsgdbv2.IMPORTANCEWe established the largest Salmonella genome database from China and presented the landscape and spatiotemporal dynamics of antimicrobial resistance genes. We also found that economic, climatic, and social factors can drive the rise of antimicrobial resistance. The Chinese local Salmonella genome database version 2 was released as an open-access database (https://nmdc.cn/clsgdbv2) and thus can assist surveillance studies across the globe. This database will help inform interventions for AMR, food safety, and public health." @default.
• W4387296291 created "2023-10-04" @default.
• W4387296291 creator A5001937247 @default.
• W4387296291 creator A5007641506 @default.
• W4387296291 creator A5023285385 @default.
• W4387296291 creator A5025019020 @default.
• W4387296291 creator A5033285179 @default.
• W4387296291 creator A5041317342 @default.
• W4387296291 creator A5044371478 @default.
• W4387296291 creator A5062432075 @default.
• W4387296291 creator A5068079814 @default.
• W4387296291 creator A5076890772 @default.
• W4387296291 creator A5087668741 @default.
• W4387296291 date "2023-10-03" @default.
• W4387296291 modified "2023-10-04" @default.
• W4387296291 title "Genomic analysis of almost 8,000 <i>Salmonella</i> genomes reveals drivers and landscape of antimicrobial resistance in China" @default.
• W4387296291 cites W1910972311 @default.
• W4387296291 cites W2032933615 @default.
• W4387296291 cites W2096093282 @default.
• W4387296291 cites W2117043113 @default.
• W4387296291 cites W2131271579 @default.
• W4387296291 cites W2143325926 @default.
• W4387296291 cites W2151141808 @default.
• W4387296291 cites W2394763400 @default.
• W4387296291 cites W2460333423 @default.
• W4387296291 cites W2508752697 @default.
• W4387296291 cites W2512280833 @default.
• W4387296291 cites W2600274517 @default.
• W4387296291 cites W2735487809 @default.
• W4387296291 cites W2739323458 @default.
• W4387296291 cites W2765301755 @default.
• W4387296291 cites W2779019546 @default.
• W4387296291 cites W2803599078 @default.
• W4387296291 cites W2803637930 @default.
• W4387296291 cites W2901209811 @default.
• W4387296291 cites W2908015311 @default.
• W4387296291 cites W2917067204 @default.
• W4387296291 cites W2918097643 @default.
• W4387296291 cites W2923824014 @default.
• W4387296291 cites W2945870797 @default.
• W4387296291 cites W2952167528 @default.
• W4387296291 cites W2955929196 @default.
• W4387296291 cites W2975535544 @default.
• W4387296291 cites W2975983989 @default.
• W4387296291 cites W2984124520 @default.
• W4387296291 cites W3003169408 @default.
• W4387296291 cites W3015857496 @default.
• W4387296291 cites W3016651859 @default.
• W4387296291 cites W3048398081 @default.
• W4387296291 cites W3083885814 @default.
• W4387296291 cites W3090034530 @default.
• W4387296291 cites W3104901023 @default.
• W4387296291 cites W3120686020 @default.
• W4387296291 cites W3124648729 @default.
• W4387296291 cites W3161115658 @default.
• W4387296291 cites W3185757133 @default.
• W4387296291 cites W3194963158 @default.
• W4387296291 cites W3206853792 @default.
• W4387296291 cites W3208203582 @default.
• W4387296291 cites W4206677002 @default.
• W4387296291 cites W4211238209 @default.
• W4387296291 cites W4212823867 @default.
• W4387296291 cites W4213070162 @default.
• W4387296291 cites W4220657016 @default.
• W4387296291 cites W4226065343 @default.
• W4387296291 cites W4281710972 @default.
• W4387296291 cites W4294018416 @default.
• W4387296291 cites W4309515816 @default.
• W4387296291 cites W4310342552 @default.
• W4387296291 cites W4311585567 @default.
• W4387296291 cites W4315620204 @default.
• W4387296291 cites W4317213719 @default.
• W4387296291 cites W4327679996 @default.
• W4387296291 cites W4362576205 @default.
• W4387296291 cites W4381332078 @default.
• W4387296291 doi "https://doi.org/10.1128/spectrum.02080-23" @default.
• W4387296291 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37787535" @default.
• W4387296291 hasPublicationYear "2023" @default.
• W4387296291 type Work @default.
• W4387296291 citedByCount "0" @default.
• W4387296291 crossrefType "journal-article" @default.
• W4387296291 hasAuthorship W4387296291A5001937247 @default.
• W4387296291 hasAuthorship W4387296291A5007641506 @default.
• W4387296291 hasAuthorship W4387296291A5023285385 @default.
• W4387296291 hasAuthorship W4387296291A5025019020 @default.
• W4387296291 hasAuthorship W4387296291A5033285179 @default.
• W4387296291 hasAuthorship W4387296291A5041317342 @default.
• W4387296291 hasAuthorship W4387296291A5044371478 @default.
• W4387296291 hasAuthorship W4387296291A5062432075 @default.
• W4387296291 hasAuthorship W4387296291A5068079814 @default.
• W4387296291 hasAuthorship W4387296291A5076890772 @default.
• W4387296291 hasAuthorship W4387296291A5087668741 @default.
• W4387296291 hasBestOaLocation W43872962911 @default.
• W4387296291 hasConcept C10389963 @default.
• W4387296291 hasConcept C104317684 @default.
• W4387296291 hasConcept C114851261 @default.
• W4387296291 hasConcept C116675565 @default.
• W4387296291 hasConcept C133936738 @default.
• W4387296291 hasConcept C141231307 @default.
• W4387296291 hasConcept C159047783 @default.

• next