FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387310789> ?p ?o ?g. }

• W4387310789 abstract "Abstract Background In 2020, the WHO-approved Molbio Truenat platform and MTB assays to detect Mycobacterium tuberculosis complex (MTB) and resistance to rifampicin directly on sputum specimens. This primary health care center-based trial in Mozambique and Tanzania investigates the effect of Truenat platform/MTB assays (intervention arm) combined with rapid communication of results compared to standard of care on TB diagnosis and treatment initiation for microbiologically confirmed TB at 7 days from enrolment. Methods The Tuberculosis Close the Gap, Increase Access, and Provide Adequate Therapy (TB-CAPT) CORE trial employs a pragmatic cluster randomized controlled design toevaluate the impact of a streamlined strategy for delivery of Truenat platform/MTB assays testingat primary health centers. Twenty-nine centers equipped with TB microscopy units were selected to participate in the trial. Among them, fifteen health centers were randomized to the intervention arm (which involves onsite molecular testing using Truenat platform/MTB assays, process process optimization to enable same-day TB diagnosis and treatment initiation, and feedback on Molbio platform performance) or the control arm (which follows routine care, including on-site sputum smear microscopy and the referral of sputum samples to off-site Xpert testing sites). The primary outcome of the study is the absolute number and proportion of participants with TB microbiological confirmation starting TB treatment within 7 days of their first visit. Secondary outcomes include time to bacteriological confirmation, health outcomes up to 60 days from first visit, as well as user preferences, direct ccost,and productivity analyses. Ethics and dissemination TB-CAPT CORE trial has been approved by regulatory and ethical committees in Mozambique and Tanzania, as well as by each partner organization. Consent is informed and voluntary, and confidentiality of participants is maintained throughout. Study findings will be presented at scientific conferences and published in peer-reviewed international journals. Trial Registration US National Institutes of Health’s ClinicalTrials.gov, NCT04568954. Registered 23 September 2020." @default.
• W4387310789 created "2023-10-04" @default.
• W4387310789 creator A5003813294 @default.
• W4387310789 creator A5008048482 @default.
• W4387310789 creator A5014012033 @default.
• W4387310789 creator A5018257487 @default.
• W4387310789 creator A5022367224 @default.
• W4387310789 creator A5026912831 @default.
• W4387310789 creator A5029655893 @default.
• W4387310789 creator A5030956784 @default.
• W4387310789 creator A5034689350 @default.
• W4387310789 creator A5038284865 @default.
• W4387310789 creator A5040417894 @default.
• W4387310789 creator A5042096114 @default.
• W4387310789 creator A5043732714 @default.
• W4387310789 creator A5044531408 @default.
• W4387310789 creator A5050069898 @default.
• W4387310789 creator A5053039202 @default.
• W4387310789 creator A5056122707 @default.
• W4387310789 creator A5057277707 @default.
• W4387310789 creator A5057619997 @default.
• W4387310789 creator A5063327384 @default.
• W4387310789 creator A5063714646 @default.
• W4387310789 creator A5065112610 @default.
• W4387310789 creator A5065996404 @default.
• W4387310789 creator A5066677332 @default.
• W4387310789 creator A5068683950 @default.
• W4387310789 creator A5070289351 @default.
• W4387310789 creator A5075109276 @default.
• W4387310789 creator A5076276637 @default.
• W4387310789 creator A5089815852 @default.
• W4387310789 creator A5090240218 @default.
• W4387310789 creator A5092995315 @default.
• W4387310789 creator A5092995316 @default.
• W4387310789 creator A5092995317 @default.
• W4387310789 date "2023-10-03" @default.
• W4387310789 modified "2023-10-10" @default.
• W4387310789 title "Study Protocol: A pragmatic, cluster-randomized controlled trial to evaluate the effect of implementation of the Truenat platform/MTB assays at primary health care clinics in Mozambique and Tanzania (TB-CAPT CORE)" @default.
• W4387310789 cites W1996650165 @default.
• W4387310789 cites W2032191478 @default.
• W4387310789 cites W2040315670 @default.
• W4387310789 cites W2102683194 @default.
• W4387310789 cites W2138664283 @default.
• W4387310789 cites W2472138188 @default.
• W4387310789 cites W2545409759 @default.
• W4387310789 cites W2753668595 @default.
• W4387310789 cites W2767797026 @default.
• W4387310789 cites W2891388866 @default.
• W4387310789 cites W2918009030 @default.
• W4387310789 cites W3009073698 @default.
• W4387310789 cites W3113746155 @default.
• W4387310789 cites W3164737901 @default.
• W4387310789 cites W3164962581 @default.
• W4387310789 cites W3188123635 @default.
• W4387310789 cites W4294281372 @default.
• W4387310789 cites W4307846395 @default.
• W4387310789 doi "https://doi.org/10.21203/rs.3.rs-3348643/v1" @default.
• W4387310789 hasPublicationYear "2023" @default.
• W4387310789 type Work @default.
• W4387310789 citedByCount "0" @default.
• W4387310789 crossrefType "posted-content" @default.
• W4387310789 hasAuthorship W4387310789A5003813294 @default.
• W4387310789 hasAuthorship W4387310789A5008048482 @default.
• W4387310789 hasAuthorship W4387310789A5014012033 @default.
• W4387310789 hasAuthorship W4387310789A5018257487 @default.
• W4387310789 hasAuthorship W4387310789A5022367224 @default.
• W4387310789 hasAuthorship W4387310789A5026912831 @default.
• W4387310789 hasAuthorship W4387310789A5029655893 @default.
• W4387310789 hasAuthorship W4387310789A5030956784 @default.
• W4387310789 hasAuthorship W4387310789A5034689350 @default.
• W4387310789 hasAuthorship W4387310789A5038284865 @default.
• W4387310789 hasAuthorship W4387310789A5040417894 @default.
• W4387310789 hasAuthorship W4387310789A5042096114 @default.
• W4387310789 hasAuthorship W4387310789A5043732714 @default.
• W4387310789 hasAuthorship W4387310789A5044531408 @default.
• W4387310789 hasAuthorship W4387310789A5050069898 @default.
• W4387310789 hasAuthorship W4387310789A5053039202 @default.
• W4387310789 hasAuthorship W4387310789A5056122707 @default.
• W4387310789 hasAuthorship W4387310789A5057277707 @default.
• W4387310789 hasAuthorship W4387310789A5057619997 @default.
• W4387310789 hasAuthorship W4387310789A5063327384 @default.
• W4387310789 hasAuthorship W4387310789A5063714646 @default.
• W4387310789 hasAuthorship W4387310789A5065112610 @default.
• W4387310789 hasAuthorship W4387310789A5065996404 @default.
• W4387310789 hasAuthorship W4387310789A5066677332 @default.
• W4387310789 hasAuthorship W4387310789A5068683950 @default.
• W4387310789 hasAuthorship W4387310789A5070289351 @default.
• W4387310789 hasAuthorship W4387310789A5075109276 @default.
• W4387310789 hasAuthorship W4387310789A5076276637 @default.
• W4387310789 hasAuthorship W4387310789A5089815852 @default.
• W4387310789 hasAuthorship W4387310789A5090240218 @default.
• W4387310789 hasAuthorship W4387310789A5092995315 @default.
• W4387310789 hasAuthorship W4387310789A5092995316 @default.
• W4387310789 hasAuthorship W4387310789A5092995317 @default.
• W4387310789 hasBestOaLocation W43873107891 @default.
• W4387310789 hasConcept C126322002 @default.
• W4387310789 hasConcept C142724271 @default.
• W4387310789 hasConcept C160735492 @default.
• W4387310789 hasConcept C162324750 @default.
• W4387310789 hasConcept C164866538 @default.

• next