Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387324562> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4387324562 endingPage "5234" @default.
- W4387324562 startingPage "5232" @default.
- W4387324562 abstract "Rhabdomyolysis may arise due to traumatic or non-traumatic causes leading to muscle injury. However, increased statin use has raised drug-related side effects like statin-related muscle damage.A 74-year-old male with liver cirrhosis secondary to alcohol was prescribed atorvastatin for hyperlipidemia. He developed muscle tenderness and decreased muscle power 2 weeks following statin therapy, evident with a creatine phosphokinase level of more than 22 000 IU/l. The urinalysis also revealed positive for blood. Hence, atorvastatin was ceased. The patient's laboratory parameters improved significantly, implying atorvastatin is the causative agent for rhabdomyolysis.Statins are usually safe and well-tolerated drugs; however, skeletal muscle symptoms occur in ~5-10% of patients. The risk factor for statin-induced muscle injury includes advanced age, drug-altering statin plasma level, liver disease, or chronic kidney disease. Moreover, the hepatic level of CYP450 and its CYP3A4 isoform are altered in chronic liver diseases. CYP3A4 isoenzyme and its activity declines in hepatic cirrhosis patients.Statins are generally prescribed for hyperlipidemia and primary and secondary prevention in high-risk cardiovascular diseases. However, several risk factors alter statin metabolism, causing statin-induced muscle injury. Thus, despite several studies suggesting otherwise, special precautions should be taken in patients with chronic liver disease." @default.
- W4387324562 created "2023-10-04" @default.
- W4387324562 creator A5002576601 @default.
- W4387324562 creator A5016403602 @default.
- W4387324562 creator A5083596655 @default.
- W4387324562 date "2023-09-01" @default.
- W4387324562 modified "2023-10-11" @default.
- W4387324562 title "Low-dose atorvastatin therapy induced rhabdomyolysis in a liver cirrhosis patient – a case report" @default.
- W4387324562 cites W1567879611 @default.
- W4387324562 cites W2006572302 @default.
- W4387324562 cites W2017687352 @default.
- W4387324562 cites W2040982838 @default.
- W4387324562 cites W2051922899 @default.
- W4387324562 cites W2075259948 @default.
- W4387324562 cites W2136466059 @default.
- W4387324562 cites W2161151577 @default.
- W4387324562 cites W2416821331 @default.
- W4387324562 cites W2552951299 @default.
- W4387324562 cites W2996779061 @default.
- W4387324562 cites W3103171760 @default.
- W4387324562 cites W4206041328 @default.
- W4387324562 cites W4288428467 @default.
- W4387324562 doi "https://doi.org/10.1097/ms9.0000000000001231" @default.
- W4387324562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37811121" @default.
- W4387324562 hasPublicationYear "2023" @default.
- W4387324562 type Work @default.
- W4387324562 citedByCount "0" @default.
- W4387324562 crossrefType "journal-article" @default.
- W4387324562 hasAuthorship W4387324562A5002576601 @default.
- W4387324562 hasAuthorship W4387324562A5016403602 @default.
- W4387324562 hasAuthorship W4387324562A5083596655 @default.
- W4387324562 hasBestOaLocation W43873245621 @default.
- W4387324562 hasConcept C126322002 @default.
- W4387324562 hasConcept C134018914 @default.
- W4387324562 hasConcept C2776637226 @default.
- W4387324562 hasConcept C2776839432 @default.
- W4387324562 hasConcept C2777075537 @default.
- W4387324562 hasConcept C2777214474 @default.
- W4387324562 hasConcept C2777300911 @default.
- W4387324562 hasConcept C2777482532 @default.
- W4387324562 hasConcept C2779091943 @default.
- W4387324562 hasConcept C2779379848 @default.
- W4387324562 hasConcept C36880943 @default.
- W4387324562 hasConcept C555293320 @default.
- W4387324562 hasConcept C71924100 @default.
- W4387324562 hasConcept C90924648 @default.
- W4387324562 hasConceptScore W4387324562C126322002 @default.
- W4387324562 hasConceptScore W4387324562C134018914 @default.
- W4387324562 hasConceptScore W4387324562C2776637226 @default.
- W4387324562 hasConceptScore W4387324562C2776839432 @default.
- W4387324562 hasConceptScore W4387324562C2777075537 @default.
- W4387324562 hasConceptScore W4387324562C2777214474 @default.
- W4387324562 hasConceptScore W4387324562C2777300911 @default.
- W4387324562 hasConceptScore W4387324562C2777482532 @default.
- W4387324562 hasConceptScore W4387324562C2779091943 @default.
- W4387324562 hasConceptScore W4387324562C2779379848 @default.
- W4387324562 hasConceptScore W4387324562C36880943 @default.
- W4387324562 hasConceptScore W4387324562C555293320 @default.
- W4387324562 hasConceptScore W4387324562C71924100 @default.
- W4387324562 hasConceptScore W4387324562C90924648 @default.
- W4387324562 hasIssue "10" @default.
- W4387324562 hasLocation W43873245621 @default.
- W4387324562 hasLocation W43873245622 @default.
- W4387324562 hasOpenAccess W4387324562 @default.
- W4387324562 hasPrimaryLocation W43873245621 @default.
- W4387324562 hasRelatedWork W1951404889 @default.
- W4387324562 hasRelatedWork W2014608182 @default.
- W4387324562 hasRelatedWork W2078434403 @default.
- W4387324562 hasRelatedWork W2086531227 @default.
- W4387324562 hasRelatedWork W2112283571 @default.
- W4387324562 hasRelatedWork W2351292305 @default.
- W4387324562 hasRelatedWork W2353588646 @default.
- W4387324562 hasRelatedWork W2356521402 @default.
- W4387324562 hasRelatedWork W2360031701 @default.
- W4387324562 hasRelatedWork W3212426150 @default.
- W4387324562 hasVolume "85" @default.
- W4387324562 isParatext "false" @default.
- W4387324562 isRetracted "false" @default.
- W4387324562 workType "article" @default.