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- W4387327133 abstract "The abdominal appendages of larval insects have a complex evolutionary history of gain and loss, but the regulatory mechanisms underlying the abdominal appendage development remain largely unclear. Here, we investigated the embryogenesis of abdominal prolegs in the scorpionfly Panorpa liui Hua (Mecoptera: Panorpidae) using in situ hybridization and parental RNA interference. The results show that RNAi-mediated knockdown of Ultrabithorax (Ubx) led to a homeotic transformation of the first abdominal segment (A1) into the third thoracic segment (T3) and changed the distributions of the downstream target Distal-less (Dll) expression but did not affect the expression levels of Dll. Knockdown of abdominal-A (abd-A) resulted in malformed segments, abnormal prolegs and disrupted Dll expression. The results demonstrate that the gene Ubx maintains an ancestral role of modulating A1 appendage fate without preventing Dll initiation, and a secondary adaptation of abd-A evolves the ability to specify abdominal segments and proleg identity. We conclude that changes in abdominal Hox gene expression and their target genes regulate abdominal appendage morphology during the evolutionary course of holometabolous larvae." @default.
- W4387327133 created "2023-10-05" @default.
- W4387327133 creator A5066205641 @default.
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- W4387327133 date "2023-10-04" @default.
- W4387327133 modified "2023-10-14" @default.
- W4387327133 title "Distinct roles of the Hox genes <i>Ultrabithorax</i> and <i>abdominal‐A</i> in scorpionfly embryonic proleg development" @default.
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- W4387327133 doi "https://doi.org/10.1111/imb.12878" @default.
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