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- W4387327833 abstract "Increasingly, clinical practice guidelines advocate a precision medicine-based approach to care for asthma. This focus requires not only knowledge of different asthma phenotypes and their associated biomarkers, but also of sex and gender differences through the lifespan. Evidence continues to build in favour of different lifetime prevalence, clinical presentations, responses to management and long-term prognosis of asthma. Women transition through many biological and psychosocial phases in their lives, all of which may interact with, and influence, their health and wellbeing. Historically, explanations have focused on hormonal effects on asthma in reproductive life, but a greater understanding of mechanisms starting before birth and changing over a lifetime is now possible, with immunologic, inflammatory and hormonal factors playing a role. This paper describes the evidence for the differences in asthma and rhinitis between men and women at different stages of life, the potential underlying mechanisms that contribute to this, and the implications for management and research. Future research studies should systematically report sex differences in asthma so that this knowledge can be used to develop a personalised approach to care, in order to achieve best possible outcomes for all." @default.
- W4387327833 created "2023-10-05" @default.
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- W4387327833 date "2023-10-01" @default.
- W4387327833 modified "2023-10-08" @default.
- W4387327833 title "Clinical commentary review for Women’s Health in Allergy/Immunology theme Asthma and rhinitis through the lifespan of non-pregnant women" @default.
- W4387327833 doi "https://doi.org/10.1016/j.jaip.2023.09.040" @default.
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