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• W4387327946 abstract "BackgroundMoyamoya angiopathy is a rare cerebral vasculopathy and an underdiagnosed cause of arterial ischemic stroke in children. We aim to report the clinical and radiological presentations in a Tunisian pediatric cohort.MethodsWe identified Moyamoya angiopathy in pediatric patients managed at the Child Neurology Department of Hedi Chaker Sfax University Hospital between 2008 and 2020 and reviewed their clinical and radiological data as well as their evolutionary profile.ResultsWe collected 14 patients with a median age of 40.6 months old and a female predominance (sex ratio of 0.75). An arterial ischemic stroke (AIS) revealed the disease in all patients, with the major symptom being a motor deficit. Symptoms related to a transient ischemic attack before the diagnosis consultation were reported in 4 patients. Carotid territory was, clinically and radiologically, the most frequently involved. Brain magnetic resonance imaging with angiography was performed in 12 patients confirming the diagnosis by revealing the development of collateral vessels. All the investigations concluded to Moyamoya disease in 57.2% and Moyamoya syndrome in 42.8%. The latter was related to Down syndrome in 5 patients and Neurofibromatosis type 1 in one patient. With a mean follow-up of 2.35 years, two patients had at least two more arterial ischemic strokes during the first two years following diagnosis, and 42.8% of patients were diagnosed with vascular or post-stroke epilepsy. A full recovery was noted in 14.3% of cases.ConclusionMoyamoya angiopathy in children is a serious condition that needs to be recognized due to the high risk of recurrent ischemic strokes." @default.
• W4387327946 created "2023-10-05" @default.
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• W4387327946 date "2023-10-01" @default.
• W4387327946 modified "2023-10-14" @default.
• W4387327946 title "Moyamoya Angiopathy: An underdiagnosed cause of ischemic stroke in a Tunisian pediatric cohort" @default.
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• W4387327946 doi "https://doi.org/10.1016/j.pediatrneurol.2023.09.017" @default.
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