Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387331487> ?p ?o ?g. }
- W4387331487 endingPage "e0284659" @default.
- W4387331487 startingPage "e0284659" @default.
- W4387331487 abstract "The coronavirus disease (COVID-19) pandemic has led to an unprecedented public health crisis. Insufficient testing continues to limit the effectiveness of the global response to the COVID-19 pandemic. Molecular testing methods such as reverse transcriptase polymerase chain reaction (RT-PCR) continue to be highly centralized and are a sub-optimal option for population surveillance. Rapid antigen tests (Ag-RDTs) offer multiple benefits including low costs, high flexibility to conduct tests in a wide variety of settings, and faster return of results. Self-test Ag-RDTs (STs) have gained approval in several markets and offer the possibility to expand testing, reaching at-risk populations. While STs have the potential to assist the COVID-19 response, test result integrity, reporting, and appropriate linkage to care continue to hinder the widespread implementation of self-testing programs. This protocol presents a mixed-methods pragmatic trial ( ISRCTN91602092 ) to better understand the feasibility of self-testing as part of a contact tracing strategy within the Brazilian public health system. Approximately 604 close contacts of 150 index cases testing positive for COVID-19 will be enrolled. Index cases will be randomized for their close contacts to participate in either serial (daily) self-testing over a 10-day follow-up period or a more traditional approach to contact tracing with a professional Ag-RDT at one time point post-exposure. Usability workshops and focus group discussions will also be conducted. This study protocol presents a comprehensive plan to assess the effectiveness, operational feasibility, and stakeholder preferences of a serial self-testing strategy for contact tracing within the Brazilian public health system. Our results will contribute to better understanding of the feasibility of a self-testing strategy within the public sector. Potential risks and limitations are discussed. Our findings will have important implications as governments continue working to mitigate the impact of COVID-19, particularly in the context of where to direct limited resources for testing and healthcare infrastructure. Registration: This trial is registered at ISCTRN ( ISRCTN91602092 )." @default.
- W4387331487 created "2023-10-05" @default.
- W4387331487 creator A5006777901 @default.
- W4387331487 creator A5033001331 @default.
- W4387331487 creator A5034555096 @default.
- W4387331487 creator A5046004181 @default.
- W4387331487 creator A5050097116 @default.
- W4387331487 creator A5060734308 @default.
- W4387331487 creator A5069834160 @default.
- W4387331487 creator A5077605174 @default.
- W4387331487 creator A5078238057 @default.
- W4387331487 creator A5088821240 @default.
- W4387331487 creator A5091407940 @default.
- W4387331487 date "2023-10-04" @default.
- W4387331487 modified "2023-10-16" @default.
- W4387331487 title "Integration of serial self-testing for COVID-19 as part of contact tracing in the Brazilian public health system: A pragmatic trial protocol" @default.
- W4387331487 cites W1596953637 @default.
- W4387331487 cites W3014281460 @default.
- W4387331487 cites W3019605310 @default.
- W4387331487 cites W3021112975 @default.
- W4387331487 cites W3090433892 @default.
- W4387331487 cites W3113945020 @default.
- W4387331487 cites W3137493192 @default.
- W4387331487 cites W3164851792 @default.
- W4387331487 cites W3192950354 @default.
- W4387331487 cites W3197383277 @default.
- W4387331487 cites W3203836895 @default.
- W4387331487 cites W3207586487 @default.
- W4387331487 cites W4200386483 @default.
- W4387331487 cites W4280535866 @default.
- W4387331487 cites W4281264688 @default.
- W4387331487 cites W4290643781 @default.
- W4387331487 cites W4323667182 @default.
- W4387331487 doi "https://doi.org/10.1371/journal.pone.0284659" @default.
- W4387331487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37792740" @default.
- W4387331487 hasPublicationYear "2023" @default.
- W4387331487 type Work @default.
- W4387331487 citedByCount "0" @default.
- W4387331487 crossrefType "journal-article" @default.
- W4387331487 hasAuthorship W4387331487A5006777901 @default.
- W4387331487 hasAuthorship W4387331487A5033001331 @default.
- W4387331487 hasAuthorship W4387331487A5034555096 @default.
- W4387331487 hasAuthorship W4387331487A5046004181 @default.
- W4387331487 hasAuthorship W4387331487A5050097116 @default.
- W4387331487 hasAuthorship W4387331487A5060734308 @default.
- W4387331487 hasAuthorship W4387331487A5069834160 @default.
- W4387331487 hasAuthorship W4387331487A5077605174 @default.
- W4387331487 hasAuthorship W4387331487A5078238057 @default.
- W4387331487 hasAuthorship W4387331487A5088821240 @default.
- W4387331487 hasAuthorship W4387331487A5091407940 @default.
- W4387331487 hasBestOaLocation W43873314871 @default.
- W4387331487 hasConcept C113162765 @default.
- W4387331487 hasConcept C138816342 @default.
- W4387331487 hasConcept C142724271 @default.
- W4387331487 hasConcept C159110408 @default.
- W4387331487 hasConcept C188598960 @default.
- W4387331487 hasConcept C199360897 @default.
- W4387331487 hasConcept C204787440 @default.
- W4387331487 hasConcept C2777904410 @default.
- W4387331487 hasConcept C2779134260 @default.
- W4387331487 hasConcept C2780385302 @default.
- W4387331487 hasConcept C2908647359 @default.
- W4387331487 hasConcept C3008058167 @default.
- W4387331487 hasConcept C41008148 @default.
- W4387331487 hasConcept C524204448 @default.
- W4387331487 hasConcept C64841741 @default.
- W4387331487 hasConcept C71924100 @default.
- W4387331487 hasConcept C89623803 @default.
- W4387331487 hasConcept C99454951 @default.
- W4387331487 hasConceptScore W4387331487C113162765 @default.
- W4387331487 hasConceptScore W4387331487C138816342 @default.
- W4387331487 hasConceptScore W4387331487C142724271 @default.
- W4387331487 hasConceptScore W4387331487C159110408 @default.
- W4387331487 hasConceptScore W4387331487C188598960 @default.
- W4387331487 hasConceptScore W4387331487C199360897 @default.
- W4387331487 hasConceptScore W4387331487C204787440 @default.
- W4387331487 hasConceptScore W4387331487C2777904410 @default.
- W4387331487 hasConceptScore W4387331487C2779134260 @default.
- W4387331487 hasConceptScore W4387331487C2780385302 @default.
- W4387331487 hasConceptScore W4387331487C2908647359 @default.
- W4387331487 hasConceptScore W4387331487C3008058167 @default.
- W4387331487 hasConceptScore W4387331487C41008148 @default.
- W4387331487 hasConceptScore W4387331487C524204448 @default.
- W4387331487 hasConceptScore W4387331487C64841741 @default.
- W4387331487 hasConceptScore W4387331487C71924100 @default.
- W4387331487 hasConceptScore W4387331487C89623803 @default.
- W4387331487 hasConceptScore W4387331487C99454951 @default.
- W4387331487 hasFunder F4320337472 @default.
- W4387331487 hasIssue "10" @default.
- W4387331487 hasLocation W43873314871 @default.
- W4387331487 hasLocation W43873314872 @default.
- W4387331487 hasOpenAccess W4387331487 @default.
- W4387331487 hasPrimaryLocation W43873314871 @default.
- W4387331487 hasRelatedWork W1989717680 @default.
- W4387331487 hasRelatedWork W2105471990 @default.
- W4387331487 hasRelatedWork W3036030877 @default.
- W4387331487 hasRelatedWork W3112369873 @default.
- W4387331487 hasRelatedWork W3204036590 @default.