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- W4387332015 abstract "Discontinuity resection is commonly conducted to avoid anastomotic leakage in high-risk patients, but potentially results in rectal stump leakage. While risk factors for anastomotic leakage have been widely studied, data on rectal stump leakage rates and underlying risk factors are scarce.To determine rectal stump leakage rates following Hartmann's procedure and to identify patient- and surgery-associated risk factors.A retrospective study with univariate and multivariate analysis to identify risk factors of rectal stump leakage was performed. A subgroup analysis of scheduled operations was carried out.The study was conducted a Heidelberg University Hospital, Germany.Patients who underwent discontinuity resection with rectal stump formation between 2010 and 2020 were included.The main outcome measures included rectal stump leakage rates, 30-day mortality, length of hospitalization and necessity for further invasive treatment.Rectal stump leakage occurred in 11.78% of patients. Rectal stump leakage rates varied considerably depending on the surgical procedure performed and were highest following subtotal pelvic exenteration (34%). Diagnosis of rectal stump leakage peaked on postoperative day 7. A short rectal stump (p = 0.001), previous pelvic radiotherapy (p = 0.04), chemotherapy (p = 0.004) and previous laparotomy (p = 0.03) were independent risk factors for rectal stump leakage in the entire patient collective. In patients undergoing scheduled surgery, a short rectal stump was the only independent risk factor (p = 0.003). Rectal stump leakage was not associated with increased 30-day mortality, but prolonged length of hospitalization and frequently necessitated further invasive treatment.Study results are limited by the retrospective design, a high number of emergency operations and the mere inclusion of symptomatic leakages.Rectal stump leakage is a relevant complication after discontinuity resection. Risk factors should be considered during surgical decision making when both discontinuity resection and abdominoperineal resection are feasible.." @default.
- W4387332015 created "2023-10-05" @default.
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- W4387332015 date "2023-10-04" @default.
- W4387332015 modified "2023-10-06" @default.
- W4387332015 title "Risk Factors for Rectal Stump Leakage following Discontinuity Resection: Stump Length Matters Most" @default.
- W4387332015 doi "https://doi.org/10.1097/dcr.0000000000002929" @default.
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