Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387336370> ?p ?o ?g. }
- W4387336370 endingPage "109132" @default.
- W4387336370 startingPage "109132" @default.
- W4387336370 abstract "Protein kinases of the MAPK cascade family (MAPKKK–MAPKK–MAPK) play an important role in the growth and development of organisms and their response to environmental stress. The MAPKK gene families in the Chinese mitten crab Eriocheir sinensis have never been systematically analyzed. We identified four MAPKK family genes, EsMEK, EsMAPKK4, EsMAPKK6, and EsMAPKK7, in E. sinensis and analyzed their molecular features and expression patterns. All four MAPKK genes are composed of multiple exons and introns, all have a conserved domain, and all have 10 conserved motifs (except EsMEK and EsMAPKK7 which are missing motif 10). The four MAPKK genes are on four different chromosomes and have no gene duplications, and the results of phylogenetic tree analysis indicate that the ESMAPKK gene family is highly conserved evolutionarily. The EsMAPKK genes were widely expressed in all the examined tissues with higher expression in hemocytes, hepatopancreas, and gills. Notably, EsMAPKK6 was also highly expressed in the ovary. Vibrio parahaemolyticus infection significantly increased the mRNA levels of the EsMAPKK genes in hemocytes. Further disruption of the EsMAPKK gene family expression affects the expression levels of multiple antimicrobial peptides in hemocytes. Our experimental results provide a starting point for a more in-depth study of the innate immunity functional roles of members of the MAPKK gene families in E. sinensis." @default.
- W4387336370 created "2023-10-05" @default.
- W4387336370 creator A5006764076 @default.
- W4387336370 creator A5013134577 @default.
- W4387336370 creator A5031185919 @default.
- W4387336370 creator A5051936772 @default.
- W4387336370 creator A5053557314 @default.
- W4387336370 creator A5059004385 @default.
- W4387336370 creator A5062908216 @default.
- W4387336370 creator A5066440546 @default.
- W4387336370 date "2023-10-01" @default.
- W4387336370 modified "2023-10-16" @default.
- W4387336370 title "Genome-wide identification and analysis of the MAPKK gene family in Chinese mitten crab (Eriocheir sinensis) and its response to bacterial challenge" @default.
- W4387336370 cites W1498079934 @default.
- W4387336370 cites W1572001733 @default.
- W4387336370 cites W1977303542 @default.
- W4387336370 cites W1981239255 @default.
- W4387336370 cites W1995176042 @default.
- W4387336370 cites W2013133956 @default.
- W4387336370 cites W2015065370 @default.
- W4387336370 cites W2017784972 @default.
- W4387336370 cites W2026345779 @default.
- W4387336370 cites W2030614920 @default.
- W4387336370 cites W2044992198 @default.
- W4387336370 cites W2047531868 @default.
- W4387336370 cites W2058336723 @default.
- W4387336370 cites W2060041263 @default.
- W4387336370 cites W2087804110 @default.
- W4387336370 cites W2093977781 @default.
- W4387336370 cites W2107277218 @default.
- W4387336370 cites W2127534631 @default.
- W4387336370 cites W2131071295 @default.
- W4387336370 cites W2136856962 @default.
- W4387336370 cites W2137450588 @default.
- W4387336370 cites W2154559315 @default.
- W4387336370 cites W2157009395 @default.
- W4387336370 cites W2159787921 @default.
- W4387336370 cites W2167096785 @default.
- W4387336370 cites W2199231372 @default.
- W4387336370 cites W2201520969 @default.
- W4387336370 cites W2342737056 @default.
- W4387336370 cites W2345630438 @default.
- W4387336370 cites W2508805055 @default.
- W4387336370 cites W2754826431 @default.
- W4387336370 cites W2889140275 @default.
- W4387336370 cites W2918698921 @default.
- W4387336370 cites W2968118097 @default.
- W4387336370 cites W2968281378 @default.
- W4387336370 cites W3025799268 @default.
- W4387336370 cites W3036319615 @default.
- W4387336370 cites W3135976858 @default.
- W4387336370 cites W3153209801 @default.
- W4387336370 cites W4221064892 @default.
- W4387336370 cites W4280535276 @default.
- W4387336370 cites W4281790889 @default.
- W4387336370 cites W4294000720 @default.
- W4387336370 cites W4296078734 @default.
- W4387336370 cites W4308452330 @default.
- W4387336370 cites W4379616576 @default.
- W4387336370 cites W568355506 @default.
- W4387336370 doi "https://doi.org/10.1016/j.fsi.2023.109132" @default.
- W4387336370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37797870" @default.
- W4387336370 hasPublicationYear "2023" @default.
- W4387336370 type Work @default.
- W4387336370 citedByCount "0" @default.
- W4387336370 crossrefType "journal-article" @default.
- W4387336370 hasAuthorship W4387336370A5006764076 @default.
- W4387336370 hasAuthorship W4387336370A5013134577 @default.
- W4387336370 hasAuthorship W4387336370A5031185919 @default.
- W4387336370 hasAuthorship W4387336370A5051936772 @default.
- W4387336370 hasAuthorship W4387336370A5053557314 @default.
- W4387336370 hasAuthorship W4387336370A5059004385 @default.
- W4387336370 hasAuthorship W4387336370A5062908216 @default.
- W4387336370 hasAuthorship W4387336370A5066440546 @default.
- W4387336370 hasBestOaLocation W43873363701 @default.
- W4387336370 hasConcept C104317684 @default.
- W4387336370 hasConcept C140793950 @default.
- W4387336370 hasConcept C141231307 @default.
- W4387336370 hasConcept C150194340 @default.
- W4387336370 hasConcept C2776408259 @default.
- W4387336370 hasConcept C2778914303 @default.
- W4387336370 hasConcept C36823959 @default.
- W4387336370 hasConcept C54355233 @default.
- W4387336370 hasConcept C5911399 @default.
- W4387336370 hasConcept C86803240 @default.
- W4387336370 hasConceptScore W4387336370C104317684 @default.
- W4387336370 hasConceptScore W4387336370C140793950 @default.
- W4387336370 hasConceptScore W4387336370C141231307 @default.
- W4387336370 hasConceptScore W4387336370C150194340 @default.
- W4387336370 hasConceptScore W4387336370C2776408259 @default.
- W4387336370 hasConceptScore W4387336370C2778914303 @default.
- W4387336370 hasConceptScore W4387336370C36823959 @default.
- W4387336370 hasConceptScore W4387336370C54355233 @default.
- W4387336370 hasConceptScore W4387336370C5911399 @default.
- W4387336370 hasConceptScore W4387336370C86803240 @default.
- W4387336370 hasLocation W43873363701 @default.
- W4387336370 hasLocation W43873363702 @default.
- W4387336370 hasOpenAccess W4387336370 @default.