FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387338082> ?p ?o ?g. }

• W4387338082 endingPage "S235" @default.
• W4387338082 startingPage "S235" @default.
• W4387338082 abstract "Spontaneous coronary artery dissection (SCAD) is an increasingly recognised cause of non-atherosclerotic myocardial infarction (MI). Systemic inflammatory diseases are commonly associated with SCAD patients, but the link between inflammatory diseases and SCAD remains unclear. The purpose of this project is to determine the prevalence of systemic inflammatory disease (SID) and elevated inflammatory markers (EIM) at SCAD presentation. To compare long-term outcomes between SCAD patients with and without SID, and with and without EIM at presentation. We reviewed patients enrolled in the Canadian SCAD Study who had laboratory measurements of inflammatory markers at presentation with SCAD. We compared the baseline demographics, presence of SID, presentation characteristics, and long-term outcomes between patients with and without SID, and between patients presenting with and without EIM at time of SCAD. SID was determined using past medical history and patient self-identification. C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were used as inflammatory biomarkers. Major adverse cardiovascular events (MACE) were defined as the composite of all-cause mortality, stroke or transient ischemic attack, MI, hospitalization for heart failure and unplanned revascularization. Of 1307 patients with SCAD, 360 had inflammatory markers measured at presentation. Of these 360 patients, 150 (43.1%) had EIM at presentation, and 13 (3.6%) reported a history of SID. Mean age was 52.9±9.8 years for patients with EIM, vs. 50.8±10.9years for patients without EIM (p=0.06). Patients with EIM had significantly higher body mass index compared to those without EIM (35.5% vs 17.6%, p=0.001). Of the patients with reported SID, there was higher prevalence of diabetes and hypertension. There was no significant difference in mean inflammatory marker levels, ESR (13.4±15.6mm/h vs 13.7±13.2mm/h, p=0.965) and CRP (15.6± 23.1mg/L vs 11.9± 26.8mg/L, p=0.644) among SID vs. no SID patients at SCAD presentation. Overall mean follow-up was 3.7±1.9 years. There was no difference in in-hospital MACE and overall MACE between patients with EIM vs. no EIM, and between SID and no SID cohorts. There were also no significant difference in angiographic findings, fibromuscular dysplasia prevalence, proportion treated conservatively vs. with revascularization in these cohorts. There was no significant difference between presentation, laboratory values, treatment, or outcomes between SCAD patients with or without SID, and between patients who present with and without EIM. This suggests that both active inflammation and history of inflammatory diseases do not contribute to SCAD or outcomes." @default.
• W4387338082 created "2023-10-05" @default.
• W4387338082 creator A5008409926 @default.
• W4387338082 creator A5027122628 @default.
• W4387338082 creator A5050460748 @default.
• W4387338082 creator A5062850057 @default.
• W4387338082 creator A5071105199 @default.
• W4387338082 date "2023-10-01" @default.
• W4387338082 modified "2023-10-06" @default.
• W4387338082 title "SYSTEMIC INFLAMMATORY DISEASE IN PATIENTS WITH SPONTANEOUS CORONARY ARTERY DISSECTION" @default.
• W4387338082 doi "https://doi.org/10.1016/j.cjca.2023.06.360" @default.
• W4387338082 hasPublicationYear "2023" @default.
• W4387338082 type Work @default.
• W4387338082 citedByCount "0" @default.
• W4387338082 crossrefType "journal-article" @default.
• W4387338082 hasAuthorship W4387338082A5008409926 @default.
• W4387338082 hasAuthorship W4387338082A5027122628 @default.
• W4387338082 hasAuthorship W4387338082A5050460748 @default.
• W4387338082 hasAuthorship W4387338082A5062850057 @default.
• W4387338082 hasAuthorship W4387338082A5071105199 @default.
• W4387338082 hasBestOaLocation W43873380821 @default.
• W4387338082 hasConcept C126322002 @default.
• W4387338082 hasConcept C127413603 @default.
• W4387338082 hasConcept C164705383 @default.
• W4387338082 hasConcept C2776857174 @default.
• W4387338082 hasConcept C2777698277 @default.
• W4387338082 hasConcept C2778213512 @default.
• W4387338082 hasConcept C2780400711 @default.
• W4387338082 hasConcept C2780645631 @default.
• W4387338082 hasConcept C2780739214 @default.
• W4387338082 hasConcept C500558357 @default.
• W4387338082 hasConcept C71924100 @default.
• W4387338082 hasConcept C78519656 @default.
• W4387338082 hasConceptScore W4387338082C126322002 @default.
• W4387338082 hasConceptScore W4387338082C127413603 @default.
• W4387338082 hasConceptScore W4387338082C164705383 @default.
• W4387338082 hasConceptScore W4387338082C2776857174 @default.
• W4387338082 hasConceptScore W4387338082C2777698277 @default.
• W4387338082 hasConceptScore W4387338082C2778213512 @default.
• W4387338082 hasConceptScore W4387338082C2780400711 @default.
• W4387338082 hasConceptScore W4387338082C2780645631 @default.
• W4387338082 hasConceptScore W4387338082C2780739214 @default.
• W4387338082 hasConceptScore W4387338082C500558357 @default.
• W4387338082 hasConceptScore W4387338082C71924100 @default.
• W4387338082 hasConceptScore W4387338082C78519656 @default.
• W4387338082 hasIssue "10" @default.
• W4387338082 hasLocation W43873380821 @default.
• W4387338082 hasOpenAccess W4387338082 @default.
• W4387338082 hasPrimaryLocation W43873380821 @default.
• W4387338082 hasRelatedWork W2089715561 @default.
• W4387338082 hasRelatedWork W2091598337 @default.
• W4387338082 hasRelatedWork W2238538201 @default.
• W4387338082 hasRelatedWork W2314081209 @default.
• W4387338082 hasRelatedWork W2417414779 @default.
• W4387338082 hasRelatedWork W2790353319 @default.
• W4387338082 hasRelatedWork W2969704120 @default.
• W4387338082 hasRelatedWork W3081075192 @default.
• W4387338082 hasRelatedWork W3083241354 @default.
• W4387338082 hasRelatedWork W3197462784 @default.
• W4387338082 hasVolume "39" @default.
• W4387338082 isParatext "false" @default.
• W4387338082 isRetracted "false" @default.
• W4387338082 workType "article" @default.