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- W4387339900 abstract "Yolk sac tumor is the second most common germ cell ovarian carcinoma. Neoadjuvant chemotherapy (NACT) is proposed as an alternative option for patients with advanced disease who are not eligible for primary debulking. We presented a case with a systematic review of advanced yolk sac tumors of the ovary with poor performance who gain benefit from NACT. A 24-year-old female underwent NACT followed by surgery after being diagnosed with an advanced yolk sac tumor. A literature search was done based on the clinical question using the Patient/Problem, Intervention, Comparison, and Outcome (PICO) approach. Pubmed and Google Scholar were used to search the literature. Out of 111 manuscripts found, 2 articles were retrieved for detailed evaluation. The patient showed a complete response in tumor size, histopathology, and tumor markers after the NACT procedure followed by surgery. NACT is a suitable option for advanced yolk sac tumors of the ovary." @default.
- W4387339900 created "2023-10-05" @default.
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- W4387339900 date "2023-10-01" @default.
- W4387339900 modified "2023-10-06" @default.
- W4387339900 title "Histopathological and biomarker complete response after neoadjuvant chemotherapy of advanced stage yolk sac tumor of the ovary: A case report and literature review" @default.
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- W4387339900 doi "https://doi.org/10.1016/j.ijscr.2023.108915" @default.
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