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- W4387339976 abstract "Orbital inflammatory pseudotumor (OIP) is a benign, non-specific inflammatory disorder that commonly occurs in middle-aged adults and is usually unilateral but can occur bilaterally. Its clinical manifestations have tremendous clinical heterogeneity and vary according to the site of infiltration and the degree of lesions, including orbital pain, swelling, diplopia, proptosis, restricted eye movement, and decreased visual acuity. Clinical features, Image characteristics and pathological examinations often need to be evaluated to confirm the diagnosis. Currently, there is no systematic research on the pathogenesis of OIP, which may be related to immunity or infection. The first-line treatment is glucocorticoids. Radiotherapy, immunosuppressants, and biologics can be considered for treatment-resistant, hormone-dependent, or intolerant patients. In this review, we aim to summarize and focus on new insights into OIP, including new diagnostic criteria, pathogenesis, and discoveries in new drugs and treatment strategies. In particular, we highlight the literature and find that T cell-mediated immune responses are closely related to the pathogenesis of OIP. Further exploration of the mechanism and signaling pathway of T cells in the immune process will help to identify their therapeutic targets and carry out targeted therapy to treat refractory OIP and reduce the side effects of traditional treatments." @default.
- W4387339976 created "2023-10-05" @default.
- W4387339976 creator A5008133107 @default.
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- W4387339976 creator A5030538673 @default.
- W4387339976 creator A5077958634 @default.
- W4387339976 date "2023-10-04" @default.
- W4387339976 modified "2023-10-08" @default.
- W4387339976 title "Orbital inflammatory pseudotumor: new advances in diagnosis, pathogenesis, and treatment" @default.
- W4387339976 cites W127254381 @default.
- W4387339976 cites W1684233627 @default.
- W4387339976 cites W1720414317 @default.
- W4387339976 cites W17285451 @default.
- W4387339976 cites W1759915280 @default.
- W4387339976 cites W1963659640 @default.
- W4387339976 cites W1967769460 @default.
- W4387339976 cites W1969617109 @default.
- W4387339976 cites W1970176244 @default.
- W4387339976 cites W1970402109 @default.
- W4387339976 cites W1971106984 @default.
- W4387339976 cites W1977332969 @default.
- W4387339976 cites W1978971215 @default.
- W4387339976 cites W1979784064 @default.
- W4387339976 cites W1980215591 @default.
- W4387339976 cites W1982151875 @default.
- W4387339976 cites W1982921283 @default.
- W4387339976 cites W1983670318 @default.
- W4387339976 cites W1984407142 @default.
- W4387339976 cites W1984833484 @default.
- W4387339976 cites W1985419111 @default.
- W4387339976 cites W1986918204 @default.
- W4387339976 cites W1995897692 @default.
- W4387339976 cites W1998232857 @default.
- W4387339976 cites W1999140904 @default.
- W4387339976 cites W2009024469 @default.
- W4387339976 cites W2010802338 @default.
- W4387339976 cites W2016298385 @default.
- W4387339976 cites W2016715128 @default.
- W4387339976 cites W2020947622 @default.
- W4387339976 cites W2024473381 @default.
- W4387339976 cites W2025008711 @default.
- W4387339976 cites W2030794839 @default.
- W4387339976 cites W2031506876 @default.
- W4387339976 cites W2035157795 @default.
- W4387339976 cites W2036696121 @default.
- W4387339976 cites W2038535814 @default.
- W4387339976 cites W2047045868 @default.
- W4387339976 cites W2050216284 @default.
- W4387339976 cites W2051361706 @default.
- W4387339976 cites W2058399345 @default.
- W4387339976 cites W2061707439 @default.
- W4387339976 cites W2063199720 @default.
- W4387339976 cites W2063470653 @default.
- W4387339976 cites W2063871323 @default.
- W4387339976 cites W2065539732 @default.
- W4387339976 cites W2069075566 @default.
- W4387339976 cites W2072505040 @default.
- W4387339976 cites W2077166822 @default.
- W4387339976 cites W2080221678 @default.
- W4387339976 cites W2081388746 @default.
- W4387339976 cites W2081833623 @default.
- W4387339976 cites W2085290932 @default.
- W4387339976 cites W2093870471 @default.
- W4387339976 cites W2096792071 @default.
- W4387339976 cites W2102039151 @default.
- W4387339976 cites W2103388828 @default.
- W4387339976 cites W2109491705 @default.
- W4387339976 cites W2110690355 @default.
- W4387339976 cites W2115909528 @default.
- W4387339976 cites W2117391225 @default.
- W4387339976 cites W2119333176 @default.
- W4387339976 cites W2122701661 @default.
- W4387339976 cites W2127751349 @default.
- W4387339976 cites W2129116380 @default.
- W4387339976 cites W2129656830 @default.
- W4387339976 cites W2130410032 @default.
- W4387339976 cites W2142387273 @default.
- W4387339976 cites W2146476621 @default.
- W4387339976 cites W2146837181 @default.
- W4387339976 cites W2147277158 @default.
- W4387339976 cites W2147940643 @default.
- W4387339976 cites W2148226248 @default.
- W4387339976 cites W2154943485 @default.
- W4387339976 cites W2159513257 @default.
- W4387339976 cites W2161092473 @default.
- W4387339976 cites W2163040935 @default.
- W4387339976 cites W2165941594 @default.
- W4387339976 cites W2236269802 @default.
- W4387339976 cites W2288372234 @default.
- W4387339976 cites W2288972139 @default.
- W4387339976 cites W2295839376 @default.
- W4387339976 cites W2301149809 @default.
- W4387339976 cites W2304411752 @default.
- W4387339976 cites W2306785562 @default.
- W4387339976 cites W2315927015 @default.
- W4387339976 cites W2319770897 @default.
- W4387339976 cites W2332796072 @default.
- W4387339976 cites W2335828340 @default.