FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387340064> ?p ?o ?g. }

• W4387340064 endingPage "155134" @default.
• W4387340064 startingPage "155134" @default.
• W4387340064 abstract "Ferroptosis is a brand-new type of controlled cell death that is distinguished by its reliance on iron and the production of lipid peroxidation. The role of ferroptosis in damaging liver disorders has attracted a lot of attention in recent years. One effective strategy to reduce liver damage is to target ferroptosis. The purpose of this review is to clarify the connection between ferroptosis and liver damage and to look into the potential contribution of natural products to the clinical management of liver damage and the discovery of novel medications. To study the methods by which natural products operate on ferroptosis to cure liver damage and their main signaling pathways, we searched databases from the time of initial publication to August 2023 in PubMed, EMBASE, Web of Science, Ovid, ScienceDirect, and China National Knowledge Infrastructure. The liver illness that each natural product treats is categorized and summarized. It's interesting to note that several natural compounds, such Artemether, Fucoidan sulfate, Curcumin, etc., have the benefit of having many targets and multiple pathways of action. We saw that in human samples or animal models of liver injury, ferroptosis indicators were activated, lipid peroxidation levels were elevated, and iron inhibitors had the ability to reduce liver damage. Liver damage can be treated with natural products by regulating ferroptosis. This is mostly accomplished through the modulation of Nrf2-related pathways (e.g., Conclusions and Astaxanthin), biological enzymes like GPX4 and the SIRT family (e.g., Chrysophanol and Decursin), and transcription factors like P53 (e.g., Artemether and Zeaxanthin). This review proposes a promising path for the therapeutic therapy of liver damage by providing a theoretical foundation for the management of ferroptosis utilizing natural ingredients." @default.
• W4387340064 created "2023-10-05" @default.
• W4387340064 creator A5012423472 @default.
• W4387340064 creator A5014947716 @default.
• W4387340064 creator A5027794948 @default.
• W4387340064 creator A5082525328 @default.
• W4387340064 date "2023-10-01" @default.
• W4387340064 modified "2023-10-08" @default.
• W4387340064 title "Targeting ferroptosis with natural products in liver injury: new insights from molecular mechanisms to targeted therapies" @default.
• W4387340064 cites W2006437314 @default.
• W4387340064 cites W2025600261 @default.
• W4387340064 cites W2291583774 @default.
• W4387340064 cites W2549188196 @default.
• W4387340064 cites W2616646839 @default.
• W4387340064 cites W2774530277 @default.
• W4387340064 cites W2804456129 @default.
• W4387340064 cites W2893163961 @default.
• W4387340064 cites W2895965610 @default.
• W4387340064 cites W2897708219 @default.
• W4387340064 cites W2911996561 @default.
• W4387340064 cites W2921084395 @default.
• W4387340064 cites W2946007903 @default.
• W4387340064 cites W2954162996 @default.
• W4387340064 cites W2964069817 @default.
• W4387340064 cites W2979799294 @default.
• W4387340064 cites W2981179816 @default.
• W4387340064 cites W2981370517 @default.
• W4387340064 cites W2981384529 @default.
• W4387340064 cites W2983890479 @default.
• W4387340064 cites W2990511618 @default.
• W4387340064 cites W2991974053 @default.
• W4387340064 cites W3000699351 @default.
• W4387340064 cites W3005253578 @default.
• W4387340064 cites W3008188366 @default.
• W4387340064 cites W3012295934 @default.
• W4387340064 cites W3012782412 @default.
• W4387340064 cites W3016176323 @default.
• W4387340064 cites W3021818653 @default.
• W4387340064 cites W3032701030 @default.
• W4387340064 cites W3043688766 @default.
• W4387340064 cites W3047457325 @default.
• W4387340064 cites W3080593150 @default.
• W4387340064 cites W3087255611 @default.
• W4387340064 cites W3087900955 @default.
• W4387340064 cites W3090693089 @default.
• W4387340064 cites W3093319781 @default.
• W4387340064 cites W3095123009 @default.
• W4387340064 cites W3097124900 @default.
• W4387340064 cites W3109596984 @default.
• W4387340064 cites W3119952098 @default.
• W4387340064 cites W3120239466 @default.
• W4387340064 cites W3122227207 @default.
• W4387340064 cites W3123970689 @default.
• W4387340064 cites W3143634367 @default.
• W4387340064 cites W3152522780 @default.
• W4387340064 cites W3153383129 @default.
• W4387340064 cites W3163901389 @default.
• W4387340064 cites W3164074301 @default.
• W4387340064 cites W3177084210 @default.
• W4387340064 cites W3182011323 @default.
• W4387340064 cites W3187945956 @default.
• W4387340064 cites W3201476493 @default.
• W4387340064 cites W3201765697 @default.
• W4387340064 cites W3202493769 @default.
• W4387340064 cites W3204215704 @default.
• W4387340064 cites W3205204506 @default.
• W4387340064 cites W3208504452 @default.
• W4387340064 cites W3209079142 @default.
• W4387340064 cites W3214299891 @default.
• W4387340064 cites W4200348394 @default.
• W4387340064 cites W4206040331 @default.
• W4387340064 cites W4206727209 @default.
• W4387340064 cites W4206972726 @default.
• W4387340064 cites W4211029020 @default.
• W4387340064 cites W4211111146 @default.
• W4387340064 cites W4213058729 @default.
• W4387340064 cites W4220834053 @default.
• W4387340064 cites W4220958165 @default.
• W4387340064 cites W4224324284 @default.
• W4387340064 cites W4283031287 @default.
• W4387340064 cites W4283779679 @default.
• W4387340064 cites W4284889683 @default.
• W4387340064 cites W4285384451 @default.
• W4387340064 cites W4289260088 @default.
• W4387340064 cites W4289638016 @default.
• W4387340064 cites W4291115283 @default.
• W4387340064 cites W4294992589 @default.
• W4387340064 cites W4295290192 @default.
• W4387340064 cites W4295872750 @default.
• W4387340064 cites W4295922660 @default.
• W4387340064 cites W4296122272 @default.
• W4387340064 cites W4296329144 @default.
• W4387340064 cites W4299805934 @default.
• W4387340064 cites W4302022990 @default.
• W4387340064 cites W4307794239 @default.
• W4387340064 cites W4308443779 @default.
• W4387340064 cites W4310256208 @default.
• W4387340064 cites W4312094691 @default.

• next