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- W4387346523 abstract "Adolescent idiopathic scoliosis (AIS) is a complex condition characterized by abnormal spinal curvature, and surgical intervention is often required to correct the deformity. However, there is significant variability in postoperative outcomes among AIS patients, suggesting the existence of distinct subgroups within this population. Using a comprehensive dataset, we employed hierarchical clustering analysis to identify subphenotypes within the AIS patient population. The statistical analysis revealed distinct subgroups characterized by unique radiographic features. Furthermore, our study demonstrated significant differences in patient-reported outcomes (PROs) among the subphenotypes, underscoring the clinical relevance of subphenotyping. This divergence in postoperative outcomes emphasizes the need for personalized treatment approaches based on individual patient characteristics. The findings of this study contribute to the current knowledge of AIS, offer insights into patient stratification, and have the potential to guide clinicians in tailoring interventions and optimizing surgical decision-making for improved patient care." @default.
- W4387346523 created "2023-10-05" @default.
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- W4387346523 date "2023-09-03" @default.
- W4387346523 modified "2023-10-06" @default.
- W4387346523 title "Adolescent Idiopathic Scoliosis Patient Subphenotyping for Surgical Planning and Improved Patient Outcomes" @default.
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- W4387346523 doi "https://doi.org/10.1145/3584371.3612957" @default.
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