FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387360984> ?p ?o ?g. }

• W4387360984 abstract "Abstract Disclosure: N. Shahid: None. L. Rudman: None. H. Maldonado Rivera: None. J. Chambi-Torres: None. J.A. Gonzalez: None. S. Valepu: None. A. Barco: None. N.H. Shaaban: None. E. Angueira: None. Background: Poorly differentiated thyroid cancer (PDTC) is a rare and aggressive form of follicular epithelial cell derived thyroid carcinoma, representing 3-5% of all thyroid cancers. As a subtype, PDTC is in a category that is between well differentiated thyrocyte malignancies and undifferentiated (anaplastic) thyroid carcinomas. Current guidelines for treatment of PDTC are not well defined. Case presentation: A 56-year-old male with a history of PDTC was admitted to the hospital directly from a correctional facility due to concern for metastasis. Patient had a total thyroidectomy performed just two months ago that revealed PDTC on surgical pathology. Recommendations at that time were to complete a full body PET-CT and follow up with radiation oncology for radiation and chemotherapy. Patient was also discharged on Synthroid 175 mcg daily for TSH suppression. However, the patient did not have any follow up appointments scheduled while at the facility. PET-CT showed stable FDG avid 2.4 cm lower right neck mass and 2 cm focus of mildly increased activity in the right lobe of the liver. On admission, a triple phase MRI liver protocol was ordered and showed a 15 mm hepatic lesion that was arterially enhancing with persistent enhancement in venous and delayed phase without dropping signal on T2 fat and additional hyperintensity on T2. Bilateral 1.7 cm adrenal nodule was also identified with relative hypointensity on T2. FNA of right neck mass was performed but did not yield sufficient tissue for pathology. Subsequent right neck exploration and skin biopsies were obtained and revealed benign fibroadipose tissue with focal fat necrosis in the thyroid and lobular capillary hemangioma in right back, left chest, and right abdomen. Patient’s status as an inmate continued to delay radiation and chemotherapy for PDTC with possible metastasis. The decision was made with the hematology/oncology inpatient consult team to perform RAI treatment with 138 mCI of I-131. Synthroid was held in anticipation of the RAI and whole body scan was ordered for 1 week after administration of I-131. Post ablation whole body scan showed intense radiotracer uptake over the region of the left and right thyroid glands and normal uptake in the stomach, small bowel, and urinary bladder. No other areas of radiotracer uptake were found. Conclusion: Diagnosis and treatment of PDTC is challenging and the social constraints as an inmate make it even more difficult to initiate appropriate therapy with radiation oncology follow up. Our case illustrates the implications of RAI ablation after total thyroidectomy in staging and therapy of PDTC. Given the intermediate histologic characteristics of PDTC, further investigation is required in the setting of metastasis and exploration of the benefits of early aggressive therapy, such as external beam radiotherapy. Presentation Date: Saturday, June 17, 2023" @default.
• W4387360984 created "2023-10-06" @default.
• W4387360984 creator A5028451408 @default.
• W4387360984 creator A5047308475 @default.
• W4387360984 creator A5051538681 @default.
• W4387360984 creator A5061147107 @default.
• W4387360984 creator A5067178167 @default.
• W4387360984 creator A5073761474 @default.
• W4387360984 creator A5082956057 @default.
• W4387360984 creator A5092102683 @default.
• W4387360984 creator A5093007099 @default.
• W4387360984 date "2023-10-01" @default.
• W4387360984 modified "2023-10-06" @default.
• W4387360984 title "SAT534 A Rare Case of Poorly Differentiated Thyroid Cancer With Extraordinary Limitations to Treatment" @default.
• W4387360984 doi "https://doi.org/10.1210/jendso/bvad114.2005" @default.
• W4387360984 hasPublicationYear "2023" @default.
• W4387360984 type Work @default.
• W4387360984 citedByCount "0" @default.
• W4387360984 crossrefType "journal-article" @default.
• W4387360984 hasAuthorship W4387360984A5028451408 @default.
• W4387360984 hasAuthorship W4387360984A5047308475 @default.
• W4387360984 hasAuthorship W4387360984A5051538681 @default.
• W4387360984 hasAuthorship W4387360984A5061147107 @default.
• W4387360984 hasAuthorship W4387360984A5067178167 @default.
• W4387360984 hasAuthorship W4387360984A5073761474 @default.
• W4387360984 hasAuthorship W4387360984A5082956057 @default.
• W4387360984 hasAuthorship W4387360984A5092102683 @default.
• W4387360984 hasAuthorship W4387360984A5093007099 @default.
• W4387360984 hasBestOaLocation W43873609841 @default.
• W4387360984 hasConcept C121608353 @default.
• W4387360984 hasConcept C126322002 @default.
• W4387360984 hasConcept C126838900 @default.
• W4387360984 hasConcept C142724271 @default.
• W4387360984 hasConcept C151730666 @default.
• W4387360984 hasConcept C187785154 @default.
• W4387360984 hasConcept C2776731575 @default.
• W4387360984 hasConcept C2777074255 @default.
• W4387360984 hasConcept C2779013556 @default.
• W4387360984 hasConcept C2779761222 @default.
• W4387360984 hasConcept C2993294228 @default.
• W4387360984 hasConcept C526584372 @default.
• W4387360984 hasConcept C71924100 @default.
• W4387360984 hasConcept C86803240 @default.
• W4387360984 hasConcept C90924648 @default.
• W4387360984 hasConceptScore W4387360984C121608353 @default.
• W4387360984 hasConceptScore W4387360984C126322002 @default.
• W4387360984 hasConceptScore W4387360984C126838900 @default.
• W4387360984 hasConceptScore W4387360984C142724271 @default.
• W4387360984 hasConceptScore W4387360984C151730666 @default.
• W4387360984 hasConceptScore W4387360984C187785154 @default.
• W4387360984 hasConceptScore W4387360984C2776731575 @default.
• W4387360984 hasConceptScore W4387360984C2777074255 @default.
• W4387360984 hasConceptScore W4387360984C2779013556 @default.
• W4387360984 hasConceptScore W4387360984C2779761222 @default.
• W4387360984 hasConceptScore W4387360984C2993294228 @default.
• W4387360984 hasConceptScore W4387360984C526584372 @default.
• W4387360984 hasConceptScore W4387360984C71924100 @default.
• W4387360984 hasConceptScore W4387360984C86803240 @default.
• W4387360984 hasConceptScore W4387360984C90924648 @default.
• W4387360984 hasIssue "Supplement_1" @default.
• W4387360984 hasLocation W43873609841 @default.
• W4387360984 hasOpenAccess W4387360984 @default.
• W4387360984 hasPrimaryLocation W43873609841 @default.
• W4387360984 hasRelatedWork W1964806738 @default.
• W4387360984 hasRelatedWork W2056973590 @default.
• W4387360984 hasRelatedWork W2088705200 @default.
• W4387360984 hasRelatedWork W2120850875 @default.
• W4387360984 hasRelatedWork W2416749483 @default.
• W4387360984 hasRelatedWork W2507809838 @default.
• W4387360984 hasRelatedWork W2913264265 @default.
• W4387360984 hasRelatedWork W4243779904 @default.
• W4387360984 hasRelatedWork W4366964559 @default.
• W4387360984 hasRelatedWork W4377691549 @default.
• W4387360984 hasVolume "7" @default.
• W4387360984 isParatext "false" @default.
• W4387360984 isRetracted "false" @default.
• W4387360984 workType "article" @default.