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- W4387363578 abstract "Post-burn pruritus is one of the most common complaints reported by patients with limited evidence for a gold-standard treatment. To review the literature and assess the efficacy of various interventions in treating post-burn pruritus. PubMed, MEDLINE, CINAHL, Web of Sciences, Ovid Databases, and ClinicalTrials.Gov were searched. The articles were scored by two assessors for inclusion with a third independent assessor resolving conflicting scores. The present systematic review and meta-analysis synthesize findings from a total of nine studies, representing a comprehensive pool of 323 patients. The standardized mean effect size for the various categories of interventions was: naltrexone at 1.47 (95% CI of 0.75-2.20, p<0.0000), coverings at 0.94 (95% CI of 0.40-1.48, p=0.006), topical ozonated oil at 2.64 (95% CI of 1.94-3.34, p<0.00001), lasers at 2.34 (95% CI of 1.60-3.09, p<0.00001), current stimulation at 1.03 (95% CI of -0.04-2.10, p=0.06), and lemon balm tea at 0.54 (95% CI of 0.12-0.96, p=0.01). Current evidence suggests that current modalities have a statistically significant, but not clinically significant, reduction in pruritus. This review highlights the limited quality of evidence in the literature and the poor quality of reporting among excluded studies." @default.
- W4387363578 created "2023-10-06" @default.
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- W4387363578 date "2023-10-01" @default.
- W4387363578 modified "2023-10-06" @default.
- W4387363578 title "Treatment of post-burn pruritus – A systematic review and meta-analysis" @default.
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- W4387363578 doi "https://doi.org/10.1016/j.burns.2023.09.012" @default.
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