Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387365061> ?p ?o ?g. }
- W4387365061 endingPage "4264" @default.
- W4387365061 startingPage "4264" @default.
- W4387365061 abstract "The direct infusion of bitter solutions in the gastrointestinal tract can reduce the secretion of orexigenic hormones and influence appetite and food intake. We aimed to explore whether oral ingestion of the bitter tastant hydroxychloroquine sulfate can exert similar effects. Ten lean adult women were included in this double-blind, randomized, two-visit, crossover study. After an overnight fast, each volunteer received film-coated tablets containing 400 mg of hydroxychloroquine sulfate (Plaquenil®) or placebo. Plasma-ghrelin, -motilin, -insulin and blood-glucose concentrations were determined every 10 min before and 30 min after feeding; appetite was scored every 10 min. Hunger scores were investigated with a special interest 50-60 min after the ingestion of hydroxychloroquine sulfate, right before a rewarding chocolate milkshake was offered to drink ad libitum. Compared with the placebo, hydroxychloroquine sulfate tended to reduce hunger at the time of interest (p = 0.10). No effect was found upon subsequent milkshake intake. Motilin plasma concentrations were unaltered, but acyl-ghrelin plasma concentrations decreased after the ingestion of hydroxychloroquine sulfate (t = 40-50; p < 0.05). These data suggest that the oral intake of hydroxychloroquine sulfate tablets reduces subjective hunger via a ghrelin-dependent mechanism but does not affect motilin release, hedonic food intake or insulin levels in healthy women." @default.
- W4387365061 created "2023-10-06" @default.
- W4387365061 creator A5014207338 @default.
- W4387365061 creator A5022514747 @default.
- W4387365061 creator A5029752566 @default.
- W4387365061 creator A5040060882 @default.
- W4387365061 creator A5045539545 @default.
- W4387365061 creator A5048668599 @default.
- W4387365061 creator A5050569044 @default.
- W4387365061 date "2023-10-05" @default.
- W4387365061 modified "2023-10-17" @default.
- W4387365061 title "The Acute Effect of Hydroxychloroquine Sulfate on Hunger, the Plasma Concentration of Orexigenic Peptides and Hedonic Food Intake: A Pilot Study" @default.
- W4387365061 cites W1578182196 @default.
- W4387365061 cites W1637971961 @default.
- W4387365061 cites W1989575442 @default.
- W4387365061 cites W1991550423 @default.
- W4387365061 cites W2003200961 @default.
- W4387365061 cites W2014389426 @default.
- W4387365061 cites W2031463048 @default.
- W4387365061 cites W2035314011 @default.
- W4387365061 cites W2051678059 @default.
- W4387365061 cites W2070578985 @default.
- W4387365061 cites W2071235764 @default.
- W4387365061 cites W2073109807 @default.
- W4387365061 cites W2075689919 @default.
- W4387365061 cites W2089885047 @default.
- W4387365061 cites W2100646932 @default.
- W4387365061 cites W2101659489 @default.
- W4387365061 cites W2106805920 @default.
- W4387365061 cites W2117569130 @default.
- W4387365061 cites W2122332643 @default.
- W4387365061 cites W2137311570 @default.
- W4387365061 cites W2139789471 @default.
- W4387365061 cites W2158287537 @default.
- W4387365061 cites W2163865122 @default.
- W4387365061 cites W2169702025 @default.
- W4387365061 cites W2263851594 @default.
- W4387365061 cites W2264728489 @default.
- W4387365061 cites W2326598752 @default.
- W4387365061 cites W2488166839 @default.
- W4387365061 cites W2506061243 @default.
- W4387365061 cites W2585424756 @default.
- W4387365061 cites W2743767942 @default.
- W4387365061 cites W2744923784 @default.
- W4387365061 cites W2795814185 @default.
- W4387365061 cites W2799787925 @default.
- W4387365061 cites W2805784908 @default.
- W4387365061 cites W2910370474 @default.
- W4387365061 cites W2950897080 @default.
- W4387365061 cites W2983775608 @default.
- W4387365061 cites W3006922930 @default.
- W4387365061 cites W3043503484 @default.
- W4387365061 cites W3123981342 @default.
- W4387365061 cites W3134011590 @default.
- W4387365061 cites W3164597429 @default.
- W4387365061 cites W4213135622 @default.
- W4387365061 cites W4221049276 @default.
- W4387365061 cites W4226048164 @default.
- W4387365061 doi "https://doi.org/10.3390/nu15194264" @default.
- W4387365061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37836548" @default.
- W4387365061 hasPublicationYear "2023" @default.
- W4387365061 type Work @default.
- W4387365061 citedByCount "0" @default.
- W4387365061 crossrefType "journal-article" @default.
- W4387365061 hasAuthorship W4387365061A5014207338 @default.
- W4387365061 hasAuthorship W4387365061A5022514747 @default.
- W4387365061 hasAuthorship W4387365061A5029752566 @default.
- W4387365061 hasAuthorship W4387365061A5040060882 @default.
- W4387365061 hasAuthorship W4387365061A5045539545 @default.
- W4387365061 hasAuthorship W4387365061A5048668599 @default.
- W4387365061 hasAuthorship W4387365061A5050569044 @default.
- W4387365061 hasBestOaLocation W43873650611 @default.
- W4387365061 hasConcept C118303440 @default.
- W4387365061 hasConcept C126322002 @default.
- W4387365061 hasConcept C131793682 @default.
- W4387365061 hasConcept C134018914 @default.
- W4387365061 hasConcept C142724271 @default.
- W4387365061 hasConcept C170493617 @default.
- W4387365061 hasConcept C185592680 @default.
- W4387365061 hasConcept C193230392 @default.
- W4387365061 hasConcept C204787440 @default.
- W4387365061 hasConcept C27081682 @default.
- W4387365061 hasConcept C2776768635 @default.
- W4387365061 hasConcept C2777205416 @default.
- W4387365061 hasConcept C2779123688 @default.
- W4387365061 hasConcept C2779134260 @default.
- W4387365061 hasConcept C2779357093 @default.
- W4387365061 hasConcept C3008058167 @default.
- W4387365061 hasConcept C524204448 @default.
- W4387365061 hasConcept C6557445 @default.
- W4387365061 hasConcept C71315377 @default.
- W4387365061 hasConcept C71924100 @default.
- W4387365061 hasConcept C75908981 @default.
- W4387365061 hasConcept C86803240 @default.
- W4387365061 hasConcept C87813604 @default.
- W4387365061 hasConcept C93984277 @default.
- W4387365061 hasConceptScore W4387365061C118303440 @default.
- W4387365061 hasConceptScore W4387365061C126322002 @default.