Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387392388> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4387392388 endingPage "e35413" @default.
- W4387392388 startingPage "e35413" @default.
- W4387392388 abstract "Rationale: Subcutaneous panniculitis like T-cell lymphoma (SPTCL) is a rare primary cutaneous lymphoma that belongs to peripheral T cell lymphomas, of which the overall prognosis is poor. Chidamide, a deacetylase inhibitor, has been approved for the treatment of peripheral T cell lymphomas. However, due to the rare occurrence of SPTCL, it is currently unknown whether Chidamide is effective for all SPTCL patients and whether there are molecular markers that can predict its therapeutic effect on SPTCL. Patient concerns and diagnoses: The patient was a sixteen-year-old male and underwent subcutaneous nodule biopsy which showed SPTCL. Next-generation sequencing revealed AT-rich interaction domain 1A ( ARID1A ) mutation, and positron emission tomography/computed tomography showed scattered subcutaneous fluorodeoxyglucose metabolic lesions throughout the body. Interventions and outcomes: During the first 3 CHOP (cyclophosphamide, doxorubicin, vindesine, and prednisone) treatment, the patient relapsed again after remission, and the successive addition of methotrexate and cyclosporine did not make the patient relapsing again. Then, after adding Chidamide to the last 3 CHOP treatment, the patient was relieved again. The patient underwent autologous hematopoietic stem cell transplantation (auto-HSCT) after completing a total of 8 cycles of chemotherapy, and continued maintenance therapy with Chidamide after auto-HSCT. Currently, the patient has been in continuous remission for 35 months. Lessons subsections: This case is the first report of a refractory/recurrent SPTCL with ARID1A mutation treated with Chidamide. The treatment of Chidamide on the basis of CHOP plus auto-HSCT therapy achieved good results, suggesting that ARID1A may act as a molecular marker to predict the therapeutic effect of Chidamide on SPTCL patients, which helps to improve the precision of SPTCL treatment and the overall prognosis of SPTCL patients." @default.
- W4387392388 created "2023-10-07" @default.
- W4387392388 creator A5004853365 @default.
- W4387392388 creator A5009318195 @default.
- W4387392388 creator A5013890334 @default.
- W4387392388 creator A5017793966 @default.
- W4387392388 creator A5043127017 @default.
- W4387392388 creator A5048903877 @default.
- W4387392388 creator A5055838753 @default.
- W4387392388 creator A5067368540 @default.
- W4387392388 creator A5083055765 @default.
- W4387392388 date "2023-10-06" @default.
- W4387392388 modified "2023-10-07" @default.
- W4387392388 title "Case report: Successful treatment of Chidamide in a refractory/recurrent SPTCL with ARID1A mutation on the basis of CHOP plus auto-HSCT" @default.
- W4387392388 cites W2584221512 @default.
- W4387392388 cites W2586777430 @default.
- W4387392388 cites W2795189660 @default.
- W4387392388 cites W2802776623 @default.
- W4387392388 cites W2882991743 @default.
- W4387392388 cites W2897562649 @default.
- W4387392388 cites W2897718232 @default.
- W4387392388 cites W2912677630 @default.
- W4387392388 cites W3015492992 @default.
- W4387392388 cites W3156651622 @default.
- W4387392388 cites W3188434637 @default.
- W4387392388 cites W3200961547 @default.
- W4387392388 cites W3214018192 @default.
- W4387392388 cites W4312221317 @default.
- W4387392388 cites W4319969393 @default.
- W4387392388 cites W4323353835 @default.
- W4387392388 cites W4328123491 @default.
- W4387392388 cites W4366083126 @default.
- W4387392388 cites W4376135760 @default.
- W4387392388 cites W4377826732 @default.
- W4387392388 doi "https://doi.org/10.1097/md.0000000000035413" @default.
- W4387392388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37800816" @default.
- W4387392388 hasPublicationYear "2023" @default.
- W4387392388 type Work @default.
- W4387392388 citedByCount "0" @default.
- W4387392388 crossrefType "journal-article" @default.
- W4387392388 hasAuthorship W4387392388A5004853365 @default.
- W4387392388 hasAuthorship W4387392388A5009318195 @default.
- W4387392388 hasAuthorship W4387392388A5013890334 @default.
- W4387392388 hasAuthorship W4387392388A5017793966 @default.
- W4387392388 hasAuthorship W4387392388A5043127017 @default.
- W4387392388 hasAuthorship W4387392388A5048903877 @default.
- W4387392388 hasAuthorship W4387392388A5055838753 @default.
- W4387392388 hasAuthorship W4387392388A5067368540 @default.
- W4387392388 hasAuthorship W4387392388A5083055765 @default.
- W4387392388 hasBestOaLocation W43873923881 @default.
- W4387392388 hasConcept C126322002 @default.
- W4387392388 hasConcept C143998085 @default.
- W4387392388 hasConcept C2776694085 @default.
- W4387392388 hasConcept C2779338263 @default.
- W4387392388 hasConcept C2779725641 @default.
- W4387392388 hasConcept C2780775027 @default.
- W4387392388 hasConcept C71924100 @default.
- W4387392388 hasConceptScore W4387392388C126322002 @default.
- W4387392388 hasConceptScore W4387392388C143998085 @default.
- W4387392388 hasConceptScore W4387392388C2776694085 @default.
- W4387392388 hasConceptScore W4387392388C2779338263 @default.
- W4387392388 hasConceptScore W4387392388C2779725641 @default.
- W4387392388 hasConceptScore W4387392388C2780775027 @default.
- W4387392388 hasConceptScore W4387392388C71924100 @default.
- W4387392388 hasIssue "40" @default.
- W4387392388 hasLocation W43873923881 @default.
- W4387392388 hasLocation W43873923882 @default.
- W4387392388 hasOpenAccess W4387392388 @default.
- W4387392388 hasPrimaryLocation W43873923881 @default.
- W4387392388 hasRelatedWork W1986862727 @default.
- W4387392388 hasRelatedWork W2024154298 @default.
- W4387392388 hasRelatedWork W2058756267 @default.
- W4387392388 hasRelatedWork W2069633902 @default.
- W4387392388 hasRelatedWork W2135044142 @default.
- W4387392388 hasRelatedWork W2302398534 @default.
- W4387392388 hasRelatedWork W2756835011 @default.
- W4387392388 hasRelatedWork W2775728428 @default.
- W4387392388 hasRelatedWork W2887770672 @default.
- W4387392388 hasRelatedWork W4200529229 @default.
- W4387392388 hasVolume "102" @default.
- W4387392388 isParatext "false" @default.
- W4387392388 isRetracted "false" @default.
- W4387392388 workType "article" @default.