FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387394582> ?p ?o ?g. }

• W4387394582 abstract "Mastitis is one of the most significant diseases in dairy cows and causes several economic losses. Somatic cell count (SCC) is often used as an indirect diagnostic tool for mastitis, especially for subclinical mastitis (SCM) where no symptoms or signs can be detected. Streptococcus agalactiae is one of the main causes of contagious mastitis, while Prototheca spp. is an alga inducing environmental mastitis that is not always correlated with increased milk SCC. The aim of this study was to evaluate the changes in the metabolomic profile of blood in relation to subclinical intramammary infection (sIMI) in dairy cows. In addition, differences due to the etiologic agent causing mastitis were also considered. Forty Holstein-Friesian dairy cows in mid and late lactation were enrolled in this study with a cross-sectional design. Based on the bacteriological examination of milk, the animals were divided into 3 groups: Group CTR (control group; n = 16); Group A (affected by SCM with IMI of Streptococcus agalactiae; n = 17); and Group P (affected by SCM with IMI of Prototheca spp.; n = 7). Blood samples were collected in tubes containing clot activator from jugular vein. The serum aliquot was stored until metabolomic analysis by 1H-NMR. Statistical analysis was conducted fitting a linear model with the group as fixed effect and SCC as covariate. Forty-two metabolites were identified and among them, 10 were significantly different among groups. Group A and P showed greater level of His and lactose, and lower level of acetate, Asn, and dimethylamine compared with Group CTR. Group A showed high level of Val, while the Group P showed also high level of Cit and methylguanidine, and lower level of 3-hydroxybutyrate, acetone, allantoin, carnitine, citrate, and ethanol. These metabolites were related to ruminal fermentations, energy metabolism, urea synthesis and metabolism, immune and inflammatory response, and mammary gland permeability. These results are suggestive of a systemic involvement of sIMI and that the metabolic profile of animals with SCM undergoes changes related to the etiological agent of mastitis." @default.
• W4387394582 created "2023-10-07" @default.
• W4387394582 creator A5004200762 @default.
• W4387394582 creator A5004403629 @default.
• W4387394582 creator A5015639675 @default.
• W4387394582 creator A5018236827 @default.
• W4387394582 creator A5022089507 @default.
• W4387394582 creator A5037898443 @default.
• W4387394582 creator A5055197677 @default.
• W4387394582 creator A5062629557 @default.
• W4387394582 creator A5063749879 @default.
• W4387394582 creator A5083843314 @default.
• W4387394582 creator A5084740655 @default.
• W4387394582 creator A5092601924 @default.
• W4387394582 creator A5093015143 @default.
• W4387394582 date "2023-10-01" @default.
• W4387394582 modified "2023-10-17" @default.
• W4387394582 title "Serum metabolome differences associated with subclinical intramammary infection caused by Streptococcus agalactiae and Prototheca spp. in multiparous dairy cows" @default.
• W4387394582 cites W1966538260 @default.
• W4387394582 cites W1973678764 @default.
• W4387394582 cites W1980707224 @default.
• W4387394582 cites W1983876940 @default.
• W4387394582 cites W2011814478 @default.
• W4387394582 cites W2021027101 @default.
• W4387394582 cites W2024482153 @default.
• W4387394582 cites W2040287157 @default.
• W4387394582 cites W2042992521 @default.
• W4387394582 cites W2061271572 @default.
• W4387394582 cites W2068580992 @default.
• W4387394582 cites W2077445149 @default.
• W4387394582 cites W2083397802 @default.
• W4387394582 cites W2083637865 @default.
• W4387394582 cites W2084735910 @default.
• W4387394582 cites W2145073188 @default.
• W4387394582 cites W2291043912 @default.
• W4387394582 cites W2547737603 @default.
• W4387394582 cites W2598704714 @default.
• W4387394582 cites W2604080057 @default.
• W4387394582 cites W2624224539 @default.
• W4387394582 cites W3013705913 @default.
• W4387394582 cites W3014679386 @default.
• W4387394582 cites W3016041999 @default.
• W4387394582 cites W3025806663 @default.
• W4387394582 cites W3041243349 @default.
• W4387394582 cites W3096594906 @default.
• W4387394582 cites W3116600078 @default.
• W4387394582 cites W3119015023 @default.
• W4387394582 cites W3123416597 @default.
• W4387394582 cites W3186439069 @default.
• W4387394582 cites W3203168925 @default.
• W4387394582 cites W4206117484 @default.
• W4387394582 cites W4210485480 @default.
• W4387394582 cites W4212847241 @default.
• W4387394582 cites W4213004060 @default.
• W4387394582 cites W4245317937 @default.
• W4387394582 cites W4298396243 @default.
• W4387394582 cites W4306403431 @default.
• W4387394582 cites W4327719818 @default.
• W4387394582 cites W4384936679 @default.
• W4387394582 cites W83408023 @default.
• W4387394582 doi "https://doi.org/10.3168/jds.2023-23851" @default.
• W4387394582 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37806625" @default.
• W4387394582 hasPublicationYear "2023" @default.
• W4387394582 type Work @default.
• W4387394582 citedByCount "0" @default.
• W4387394582 crossrefType "journal-article" @default.
• W4387394582 hasAuthorship W4387394582A5004200762 @default.
• W4387394582 hasAuthorship W4387394582A5004403629 @default.
• W4387394582 hasAuthorship W4387394582A5015639675 @default.
• W4387394582 hasAuthorship W4387394582A5018236827 @default.
• W4387394582 hasAuthorship W4387394582A5022089507 @default.
• W4387394582 hasAuthorship W4387394582A5037898443 @default.
• W4387394582 hasAuthorship W4387394582A5055197677 @default.
• W4387394582 hasAuthorship W4387394582A5062629557 @default.
• W4387394582 hasAuthorship W4387394582A5063749879 @default.
• W4387394582 hasAuthorship W4387394582A5083843314 @default.
• W4387394582 hasAuthorship W4387394582A5084740655 @default.
• W4387394582 hasAuthorship W4387394582A5092601924 @default.
• W4387394582 hasAuthorship W4387394582A5093015143 @default.
• W4387394582 hasBestOaLocation W43873945821 @default.
• W4387394582 hasConcept C113280763 @default.
• W4387394582 hasConcept C126322002 @default.
• W4387394582 hasConcept C140793950 @default.
• W4387394582 hasConcept C22641795 @default.
• W4387394582 hasConcept C2776344049 @default.
• W4387394582 hasConcept C2776659692 @default.
• W4387394582 hasConcept C2776792119 @default.
• W4387394582 hasConcept C2776799230 @default.
• W4387394582 hasConcept C2776977481 @default.
• W4387394582 hasConcept C2777785397 @default.
• W4387394582 hasConcept C2777860557 @default.
• W4387394582 hasConcept C2778276568 @default.
• W4387394582 hasConcept C2779234561 @default.
• W4387394582 hasConcept C42972112 @default.
• W4387394582 hasConcept C523546767 @default.
• W4387394582 hasConcept C54355233 @default.
• W4387394582 hasConcept C71924100 @default.
• W4387394582 hasConcept C86803240 @default.
• W4387394582 hasConcept C89423630 @default.
• W4387394582 hasConceptScore W4387394582C113280763 @default.

• next