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• W4387396907 abstract "Purslane (P), chard (CHA), and chicory (CHI) leaf extracts are individually and traditionally used in the treatment of diabetes mellitus. Polyphenols, flavonoids, the polyphenolic profile of the extracts, and their antioxidant activity were determined. This study evaluated the antidiabetic activity of combinations of these extracts in streptozotocin-induced diabetic rats. Diabetic groups were administered orally and daily for 40 days with the investigated extracts at 250 mg/kg body weight (b.w.) or metformin (100 mg/kg b.w.) as a drug. Fasting blood glucose, oral glucose tolerance, insulin, and fructosamine were assessed. The combined extracts with high levels of P or CHI exerted potent hypoglycemic activity compared with metformin in addition to the restoration of the histopathological changes in the liver and pancreas of diabetic rats to a near-normal state. Therefore, these combined extracts could be developed as natural drugs for diabetes." @default.
• W4387396907 created "2023-10-07" @default.
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• W4387396907 date "2023-10-06" @default.
• W4387396907 modified "2023-10-08" @default.
• W4387396907 title "Antidiabetic Effect of Combined Leaf Extracts of <i>Portulaca oleracea</i> L., <i>Beta vulgaris</i> L., and <i>Cichorium intybus</i> L. in Streptozotocin-Induced Diabetic Rats" @default.
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• W4387396907 doi "https://doi.org/10.1089/jmf.2022.0119" @default.
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• W4387396907 hasPublicationYear "2023" @default.
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