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- W4387396908 abstract "Abstract The research aimed to identify and characterize genes associated with drought tolerance in Nigerian common beans using Genome-Wide Association Studies. A total of 200 common bean accessions and their phenotypic data were used for the study. The bean accessions were genotyped using the BARCBean6K_3 Infinium BeadChips and SNPs were called using Genome Studio V2011.1. A filtering process was applied to remove any SNPs that had a high missing data rate (> 10%), a high heterozygosity rate (> 10%), or a low minor allele frequency (< 5%). The remaining SNPs were 3385, which were used for data analysis using GLM, MLM, and FARM-CPU statistical models corrected with PCA and Kinship to detect significant SNPs. These SNPs were then identified using the Andean whole-genome reference sequence Pvulgaris442_v2.1 for candidate genes within 50 kilobases (50kb) on either side of the SNPs. The results of the study revealed that the SNP density within 1 Megabase (Mb) regions showed significant variation in Pv02, Pv03, Pv04, Pv07, Pv08, and Pv11, indicating that these regions likely contain genes associated with drought tolerance. A total of 7 significant SNPs (S2_48101058, S3_8020543, S7_613684, S7_4257528, S8_57314881, S4_18561541 and S4_40027357) were identified, which yielded 10 candidate genes for drought tolerance. Four genes (Phvul.001G032600, Phvul.001G064300, Phvul.001G063500 and Phvul.001G064000) were reported to be involved in drought-tolerance, response to osmotic stress and response to water stress. The remaining six genes (Phvul.001G031900, Phvul.001G031300, Phvul.001G037000, Phvul.001G037100, Phvul.001G037200 and Phvul.001G067300) were enzymes and proteins responsible for plant growth and development, as well as for their resistance to environmental stress. The findings of the research contribute to the understanding of the genetic basis of drought tolerance in common beans, which can be applied to other crop species and regions." @default.
- W4387396908 created "2023-10-07" @default.
- W4387396908 creator A5092937084 @default.
- W4387396908 date "2023-10-06" @default.
- W4387396908 modified "2023-10-07" @default.
- W4387396908 title "Characterisation and Prediction of Drought-Tolerance Genes of Nigerian Common Beans using Genome-Wide Association Studies" @default.
- W4387396908 doi "https://doi.org/10.21203/rs.3.rs-3378676/v1" @default.
- W4387396908 hasPublicationYear "2023" @default.
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