Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387397493> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W4387397493 endingPage "11" @default.
- W4387397493 startingPage "1" @default.
- W4387397493 abstract "Gene therapy is gaining researchers interest to be a beneficial armamentarium in the treatment of various acquired and inherited diseases. Hydrogels carry the good potential to modify present gene therapy due to their superior biocompatibility, capability to mimic an environment that supports new cells and tissue growth, and regulate gene delivery to promote differentiation and improve therapeutic after effects. Hydrogel can also be integrated with genes to initiate differentiation for tissue regeneration. An emerging promising strategy is to design hydrogel for dual cell and genetic material distribution utilized to engineer the bones and tissue to stem cell differentiation down the chondrogenic lineage to produce cartilage. Hydrogel-based delivery of genes was also investigated for the repair of cardiac tissue and coding of Plasmid DNA. Hydrogel bio-materials can overcome barriers to gene therapy by meticulously regulating the expression of transgene vectors. The limitations include preventing genotoxicity arising from integrated vectors for gene delivery, regulating genome off targeting, increasing transfer efficacy of genes to a level effective for cure of ailments, reducing the body's defenses generated by vectors administered in-vivo , moving to common consent for dealing with concerns like justified germline editing. The emerging scope of hydrogel for gene therapy, and its multi-variant aids for the well-being of living beings, as studied via technical innovations along with scientific accomplishments across earlier numerous ages, supports continual hopefulness along with escalating hard work for formulating the delivery system best amongst treatment of serious diseases." @default.
- W4387397493 created "2023-10-07" @default.
- W4387397493 creator A5058073662 @default.
- W4387397493 creator A5087073317 @default.
- W4387397493 date "2023-10-05" @default.
- W4387397493 modified "2023-10-07" @default.
- W4387397493 title "Biocompatible Hydrogels for Gene Therapy" @default.
- W4387397493 cites W1966077496 @default.
- W4387397493 cites W1977268622 @default.
- W4387397493 cites W1994153893 @default.
- W4387397493 cites W2003414091 @default.
- W4387397493 cites W2029061676 @default.
- W4387397493 cites W2044609602 @default.
- W4387397493 cites W2138735409 @default.
- W4387397493 cites W2737085547 @default.
- W4387397493 cites W2765956829 @default.
- W4387397493 cites W2802784789 @default.
- W4387397493 cites W2921068879 @default.
- W4387397493 cites W2936178813 @default.
- W4387397493 cites W2970769725 @default.
- W4387397493 cites W3148310058 @default.
- W4387397493 doi "https://doi.org/10.1002/9781394175635.ch1" @default.
- W4387397493 hasPublicationYear "2023" @default.
- W4387397493 type Work @default.
- W4387397493 citedByCount "0" @default.
- W4387397493 crossrefType "other" @default.
- W4387397493 hasAuthorship W4387397493A5058073662 @default.
- W4387397493 hasAuthorship W4387397493A5087073317 @default.
- W4387397493 hasConcept C102230213 @default.
- W4387397493 hasConcept C104317684 @default.
- W4387397493 hasConcept C108586683 @default.
- W4387397493 hasConcept C10882517 @default.
- W4387397493 hasConcept C111599444 @default.
- W4387397493 hasConcept C135983454 @default.
- W4387397493 hasConcept C144501496 @default.
- W4387397493 hasConcept C178790620 @default.
- W4387397493 hasConcept C185592680 @default.
- W4387397493 hasConcept C28328180 @default.
- W4387397493 hasConcept C54355233 @default.
- W4387397493 hasConcept C86803240 @default.
- W4387397493 hasConcept C95444343 @default.
- W4387397493 hasConcept C98108389 @default.
- W4387397493 hasConceptScore W4387397493C102230213 @default.
- W4387397493 hasConceptScore W4387397493C104317684 @default.
- W4387397493 hasConceptScore W4387397493C108586683 @default.
- W4387397493 hasConceptScore W4387397493C10882517 @default.
- W4387397493 hasConceptScore W4387397493C111599444 @default.
- W4387397493 hasConceptScore W4387397493C135983454 @default.
- W4387397493 hasConceptScore W4387397493C144501496 @default.
- W4387397493 hasConceptScore W4387397493C178790620 @default.
- W4387397493 hasConceptScore W4387397493C185592680 @default.
- W4387397493 hasConceptScore W4387397493C28328180 @default.
- W4387397493 hasConceptScore W4387397493C54355233 @default.
- W4387397493 hasConceptScore W4387397493C86803240 @default.
- W4387397493 hasConceptScore W4387397493C95444343 @default.
- W4387397493 hasConceptScore W4387397493C98108389 @default.
- W4387397493 hasLocation W43873974931 @default.
- W4387397493 hasOpenAccess W4387397493 @default.
- W4387397493 hasPrimaryLocation W43873974931 @default.
- W4387397493 hasRelatedWork W2603161682 @default.
- W4387397493 hasRelatedWork W2807464733 @default.
- W4387397493 hasRelatedWork W2960163646 @default.
- W4387397493 hasRelatedWork W2991257722 @default.
- W4387397493 hasRelatedWork W3030388918 @default.
- W4387397493 hasRelatedWork W3165203721 @default.
- W4387397493 hasRelatedWork W4200005163 @default.
- W4387397493 hasRelatedWork W4213248511 @default.
- W4387397493 hasRelatedWork W4220766053 @default.
- W4387397493 hasRelatedWork W4366822718 @default.
- W4387397493 isParatext "false" @default.
- W4387397493 isRetracted "false" @default.
- W4387397493 workType "other" @default.