Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387405145> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W4387405145 abstract "Abstract The use of enzymes represents an approach to combat bacterial infections by degrading extracellular biomolecules to disperse Staphylococcus aureus biofilms. Commercial enzyme preparations, including cellulase, amylase, pectinase, zymolyase, and pepsin, exhibit concentration-dependent dispersion of S. aureus biofilms. Here, we report that low concentrations of these enzymes generally lack synergy when combined or added together sequentially to biofilms. Only the addition of a protease (pepsin) followed by a commercial mixture of degradative enzymes from Arthrobacter luteus (zymolyase 20T), demonstrated synergy and was effective at dispersing S. aureus biofilms. A more purified mixture of Arthrobacter luteus enzymes (zymolyase 100T) showed improved dispersal of S. aureus biofilms compared to zymolyase 20T but lacked synergy with pepsin. This study emphasizes the complexity of enzymatic biofilm dispersal and the need for tailored approaches based on the properties of degradative enzymes and biofilm composition." @default.
- W4387405145 created "2023-10-07" @default.
- W4387405145 creator A5002412654 @default.
- W4387405145 creator A5019027024 @default.
- W4387405145 date "2023-10-05" @default.
- W4387405145 modified "2023-10-18" @default.
- W4387405145 title "An apparent lack of synergy between degradative enzymes against Staphylococcus aureus biofilms" @default.
- W4387405145 cites W1826756925 @default.
- W4387405145 cites W1828067509 @default.
- W4387405145 cites W1982737710 @default.
- W4387405145 cites W1987400078 @default.
- W4387405145 cites W2036625054 @default.
- W4387405145 cites W2054352903 @default.
- W4387405145 cites W2057788460 @default.
- W4387405145 cites W2062128984 @default.
- W4387405145 cites W2070300719 @default.
- W4387405145 cites W2120692642 @default.
- W4387405145 cites W2143606104 @default.
- W4387405145 cites W2155560009 @default.
- W4387405145 cites W2156382695 @default.
- W4387405145 cites W2159617230 @default.
- W4387405145 cites W2171782979 @default.
- W4387405145 cites W2268992366 @default.
- W4387405145 cites W2337278970 @default.
- W4387405145 cites W2509458158 @default.
- W4387405145 cites W2550697572 @default.
- W4387405145 cites W2595890601 @default.
- W4387405145 cites W2797539634 @default.
- W4387405145 cites W2897240040 @default.
- W4387405145 cites W2900643491 @default.
- W4387405145 cites W2938568837 @default.
- W4387405145 cites W2941974751 @default.
- W4387405145 cites W2988260234 @default.
- W4387405145 cites W3003933287 @default.
- W4387405145 cites W3011690642 @default.
- W4387405145 cites W3044084232 @default.
- W4387405145 cites W3110783506 @default.
- W4387405145 cites W4200341743 @default.
- W4387405145 cites W4211163608 @default.
- W4387405145 cites W4225630704 @default.
- W4387405145 cites W4317933083 @default.
- W4387405145 cites W4367047930 @default.
- W4387405145 doi "https://doi.org/10.1101/2023.10.05.561034" @default.
- W4387405145 hasPublicationYear "2023" @default.
- W4387405145 type Work @default.
- W4387405145 citedByCount "0" @default.
- W4387405145 crossrefType "posted-content" @default.
- W4387405145 hasAuthorship W4387405145A5002412654 @default.
- W4387405145 hasAuthorship W4387405145A5019027024 @default.
- W4387405145 hasBestOaLocation W43874051451 @default.
- W4387405145 hasConcept C141603559 @default.
- W4387405145 hasConcept C16311235 @default.
- W4387405145 hasConcept C181199279 @default.
- W4387405145 hasConcept C185592680 @default.
- W4387405145 hasConcept C2775976474 @default.
- W4387405145 hasConcept C2776683811 @default.
- W4387405145 hasConcept C2776714187 @default.
- W4387405145 hasConcept C2779489039 @default.
- W4387405145 hasConcept C523546767 @default.
- W4387405145 hasConcept C54355233 @default.
- W4387405145 hasConcept C55493867 @default.
- W4387405145 hasConcept C58123911 @default.
- W4387405145 hasConcept C86803240 @default.
- W4387405145 hasConcept C89423630 @default.
- W4387405145 hasConceptScore W4387405145C141603559 @default.
- W4387405145 hasConceptScore W4387405145C16311235 @default.
- W4387405145 hasConceptScore W4387405145C181199279 @default.
- W4387405145 hasConceptScore W4387405145C185592680 @default.
- W4387405145 hasConceptScore W4387405145C2775976474 @default.
- W4387405145 hasConceptScore W4387405145C2776683811 @default.
- W4387405145 hasConceptScore W4387405145C2776714187 @default.
- W4387405145 hasConceptScore W4387405145C2779489039 @default.
- W4387405145 hasConceptScore W4387405145C523546767 @default.
- W4387405145 hasConceptScore W4387405145C54355233 @default.
- W4387405145 hasConceptScore W4387405145C55493867 @default.
- W4387405145 hasConceptScore W4387405145C58123911 @default.
- W4387405145 hasConceptScore W4387405145C86803240 @default.
- W4387405145 hasConceptScore W4387405145C89423630 @default.
- W4387405145 hasLocation W43874051451 @default.
- W4387405145 hasOpenAccess W4387405145 @default.
- W4387405145 hasPrimaryLocation W43874051451 @default.
- W4387405145 hasRelatedWork W1502608356 @default.
- W4387405145 hasRelatedWork W2023483837 @default.
- W4387405145 hasRelatedWork W2348156948 @default.
- W4387405145 hasRelatedWork W2366374576 @default.
- W4387405145 hasRelatedWork W2375557441 @default.
- W4387405145 hasRelatedWork W2377280289 @default.
- W4387405145 hasRelatedWork W2378290474 @default.
- W4387405145 hasRelatedWork W2391997600 @default.
- W4387405145 hasRelatedWork W2613682111 @default.
- W4387405145 hasRelatedWork W4307539528 @default.
- W4387405145 isParatext "false" @default.
- W4387405145 isRetracted "false" @default.
- W4387405145 workType "article" @default.