Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387405158> ?p ?o ?g. }
- W4387405158 endingPage "376" @default.
- W4387405158 startingPage "370" @default.
- W4387405158 abstract "The cultivar Nulichal, a type of naked waxy barley (Hordeum vulgare L.), was developed by the National Institute of Crop Science, Rural Development Administration, Korea, in 2010. In this study, we investigated the anti-inflammatory and antioxidant properties of the Nulichal ethanol extract (NRE) using various assays. The NRE exhibited a total phenolic content of 7.55±0.30 mg gallic acid equivalent/g and a flavonoid content of 1.74±0.08 mg rutin equivalent/g. Cell viability assays showed no toxicity of NRE on RAW264.7 macrophage cells up to concentrations of 500 μg/mL. The NRE (300 and 500 μg/mL) significantly reduced nitric oxide (NO) production induced by lipopolysaccharides (LPS). It also down-regulated the mRNA expression and protein levels of inducible NO synthase and cyclooxygenase-2 in a dose-dependent manner. Moreover, the NRE treatment significantly decreased the levels of pro-inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6, and their mRNA expression compared to LPS treatment alone. The NRE demonstrated strong free radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radicals in a dose-dependent manner. The ferric reducing antioxidant power assay also showed increased antioxidant activity with increasing NRE concentrations. These findings suggest that the NRE can be used as a functional food with anti-inflammatory and antioxidant properties." @default.
- W4387405158 created "2023-10-07" @default.
- W4387405158 creator A5010415261 @default.
- W4387405158 creator A5040266876 @default.
- W4387405158 creator A5046156960 @default.
- W4387405158 creator A5068338849 @default.
- W4387405158 creator A5078867271 @default.
- W4387405158 creator A5082329721 @default.
- W4387405158 date "2023-09-30" @default.
- W4387405158 modified "2023-10-18" @default.
- W4387405158 title "“Nulichal” Barley Extract Suppresses Nitric Oxide and Pro-Inflammatory Cytokine Production by Lipopolysaccharides in RAW264.7 Macrophage Cell Line" @default.
- W4387405158 cites W1067198858 @default.
- W4387405158 cites W1550722396 @default.
- W4387405158 cites W1974081986 @default.
- W4387405158 cites W2000770184 @default.
- W4387405158 cites W2005616543 @default.
- W4387405158 cites W2007043238 @default.
- W4387405158 cites W2017306058 @default.
- W4387405158 cites W2025088826 @default.
- W4387405158 cites W2026818910 @default.
- W4387405158 cites W2035656016 @default.
- W4387405158 cites W2044191946 @default.
- W4387405158 cites W2047512700 @default.
- W4387405158 cites W2062161568 @default.
- W4387405158 cites W2063299574 @default.
- W4387405158 cites W2065037435 @default.
- W4387405158 cites W2094156327 @default.
- W4387405158 cites W2107277218 @default.
- W4387405158 cites W2149979963 @default.
- W4387405158 cites W2162600166 @default.
- W4387405158 cites W2192080449 @default.
- W4387405158 cites W2521574223 @default.
- W4387405158 cites W2530157596 @default.
- W4387405158 cites W2797804163 @default.
- W4387405158 cites W2908798913 @default.
- W4387405158 cites W2939874894 @default.
- W4387405158 cites W3006122165 @default.
- W4387405158 cites W3037957113 @default.
- W4387405158 cites W3187502852 @default.
- W4387405158 cites W782340532 @default.
- W4387405158 doi "https://doi.org/10.3746/pnf.2023.28.3.370" @default.
- W4387405158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37842259" @default.
- W4387405158 hasPublicationYear "2023" @default.
- W4387405158 type Work @default.
- W4387405158 citedByCount "0" @default.
- W4387405158 crossrefType "journal-article" @default.
- W4387405158 hasAuthorship W4387405158A5010415261 @default.
- W4387405158 hasAuthorship W4387405158A5040266876 @default.
- W4387405158 hasAuthorship W4387405158A5046156960 @default.
- W4387405158 hasAuthorship W4387405158A5068338849 @default.
- W4387405158 hasAuthorship W4387405158A5078867271 @default.
- W4387405158 hasAuthorship W4387405158A5082329721 @default.
- W4387405158 hasBestOaLocation W43874051581 @default.
- W4387405158 hasConcept C178790620 @default.
- W4387405158 hasConcept C17991360 @default.
- W4387405158 hasConcept C185592680 @default.
- W4387405158 hasConcept C190283241 @default.
- W4387405158 hasConcept C203014093 @default.
- W4387405158 hasConcept C2777622882 @default.
- W4387405158 hasConcept C2778004101 @default.
- W4387405158 hasConcept C2778362808 @default.
- W4387405158 hasConcept C2778690821 @default.
- W4387405158 hasConcept C2993665447 @default.
- W4387405158 hasConcept C46757340 @default.
- W4387405158 hasConcept C519581460 @default.
- W4387405158 hasConcept C53227056 @default.
- W4387405158 hasConcept C55493867 @default.
- W4387405158 hasConcept C59822182 @default.
- W4387405158 hasConcept C86803240 @default.
- W4387405158 hasConcept C98274493 @default.
- W4387405158 hasConceptScore W4387405158C178790620 @default.
- W4387405158 hasConceptScore W4387405158C17991360 @default.
- W4387405158 hasConceptScore W4387405158C185592680 @default.
- W4387405158 hasConceptScore W4387405158C190283241 @default.
- W4387405158 hasConceptScore W4387405158C203014093 @default.
- W4387405158 hasConceptScore W4387405158C2777622882 @default.
- W4387405158 hasConceptScore W4387405158C2778004101 @default.
- W4387405158 hasConceptScore W4387405158C2778362808 @default.
- W4387405158 hasConceptScore W4387405158C2778690821 @default.
- W4387405158 hasConceptScore W4387405158C2993665447 @default.
- W4387405158 hasConceptScore W4387405158C46757340 @default.
- W4387405158 hasConceptScore W4387405158C519581460 @default.
- W4387405158 hasConceptScore W4387405158C53227056 @default.
- W4387405158 hasConceptScore W4387405158C55493867 @default.
- W4387405158 hasConceptScore W4387405158C59822182 @default.
- W4387405158 hasConceptScore W4387405158C86803240 @default.
- W4387405158 hasConceptScore W4387405158C98274493 @default.
- W4387405158 hasFunder F4320322035 @default.
- W4387405158 hasIssue "3" @default.
- W4387405158 hasLocation W43874051581 @default.
- W4387405158 hasLocation W43874051582 @default.
- W4387405158 hasOpenAccess W4387405158 @default.
- W4387405158 hasPrimaryLocation W43874051581 @default.
- W4387405158 hasRelatedWork W1973054716 @default.
- W4387405158 hasRelatedWork W1998792901 @default.
- W4387405158 hasRelatedWork W2002027447 @default.
- W4387405158 hasRelatedWork W2028156322 @default.
- W4387405158 hasRelatedWork W2050559178 @default.