Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387408712> ?p ?o ?g. }
- W4387408712 endingPage "3671" @default.
- W4387408712 startingPage "3671" @default.
- W4387408712 abstract "The browning of white adipocytes may be an innovative approach to address obesity. This study investigated the effects of rabbit meat extract on 3T3−L1 adipocytes, with a specific emphasis on inducing browning. The browning effects of rabbit meat extract were evaluated by analyzing genes specifically expressed in 3T3−L1 adipocytes using quantitative PCR and immunoblotting. Rabbit meat extract increased the expression of brown adipocyte−specific markers, UCP1 and PGC1α, and mitochondrial biogenesis factors, TFAM and NRF1, without affecting cell viability in fully differentiated 3T3−L1 adipocytes. Moreover, adipocyte differentiation and the triglyceride content were decreased; hormone−sensitive lipase activity was promoted. Rabbit meat extract activated the AMPK pathway in the differentiated 3T3−L1 cells. However, in adipocytes treated with rabbit meat extract, the expression of genes related to browning was reduced by the AMP−activated protein kinase (AMPK) inhibitor, dorsomorphin dihydrochloride. To the best of our knowledge, this is the first study to demonstrate that rabbit meat extract induces the browning of white adipocytes via the activation of the AMPK pathway, thereby demonstrating its therapeutic potential in preventing obesity." @default.
- W4387408712 created "2023-10-07" @default.
- W4387408712 creator A5005766074 @default.
- W4387408712 creator A5015137786 @default.
- W4387408712 creator A5035008413 @default.
- W4387408712 creator A5050194136 @default.
- W4387408712 creator A5054657906 @default.
- W4387408712 creator A5066997568 @default.
- W4387408712 creator A5069914511 @default.
- W4387408712 creator A5072052123 @default.
- W4387408712 creator A5075576655 @default.
- W4387408712 creator A5084529215 @default.
- W4387408712 date "2023-10-06" @default.
- W4387408712 modified "2023-10-17" @default.
- W4387408712 title "Rabbit Meat Extract Induces Browning in 3T3−L1 Adipocytes via the AMP−Activated Protein Kinase Pathway" @default.
- W4387408712 cites W1902842407 @default.
- W4387408712 cites W2049429989 @default.
- W4387408712 cites W2077991483 @default.
- W4387408712 cites W2157531778 @default.
- W4387408712 cites W2161217361 @default.
- W4387408712 cites W2204725108 @default.
- W4387408712 cites W2279581583 @default.
- W4387408712 cites W2521563392 @default.
- W4387408712 cites W2696298149 @default.
- W4387408712 cites W2727205166 @default.
- W4387408712 cites W2758567241 @default.
- W4387408712 cites W2885243150 @default.
- W4387408712 cites W2892041647 @default.
- W4387408712 cites W2897586598 @default.
- W4387408712 cites W2899221139 @default.
- W4387408712 cites W2902121131 @default.
- W4387408712 cites W2903848597 @default.
- W4387408712 cites W2906677090 @default.
- W4387408712 cites W2944549000 @default.
- W4387408712 cites W2996861404 @default.
- W4387408712 cites W3008459192 @default.
- W4387408712 cites W3040340804 @default.
- W4387408712 cites W3045669994 @default.
- W4387408712 cites W3111751491 @default.
- W4387408712 cites W3117237609 @default.
- W4387408712 cites W3153485041 @default.
- W4387408712 cites W3157249905 @default.
- W4387408712 cites W3193874458 @default.
- W4387408712 cites W4206952880 @default.
- W4387408712 cites W4282541874 @default.
- W4387408712 cites W4288084174 @default.
- W4387408712 cites W4295021430 @default.
- W4387408712 cites W4307366500 @default.
- W4387408712 cites W4323320860 @default.
- W4387408712 cites W4327602581 @default.
- W4387408712 cites W4366212091 @default.
- W4387408712 cites W4380985593 @default.
- W4387408712 cites W4383047169 @default.
- W4387408712 cites W4384665887 @default.
- W4387408712 cites W4385515325 @default.
- W4387408712 cites W4385564459 @default.
- W4387408712 doi "https://doi.org/10.3390/foods12193671" @default.
- W4387408712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37835324" @default.
- W4387408712 hasPublicationYear "2023" @default.
- W4387408712 type Work @default.
- W4387408712 citedByCount "0" @default.
- W4387408712 crossrefType "journal-article" @default.
- W4387408712 hasAuthorship W4387408712A5005766074 @default.
- W4387408712 hasAuthorship W4387408712A5015137786 @default.
- W4387408712 hasAuthorship W4387408712A5035008413 @default.
- W4387408712 hasAuthorship W4387408712A5050194136 @default.
- W4387408712 hasAuthorship W4387408712A5054657906 @default.
- W4387408712 hasAuthorship W4387408712A5066997568 @default.
- W4387408712 hasAuthorship W4387408712A5069914511 @default.
- W4387408712 hasAuthorship W4387408712A5072052123 @default.
- W4387408712 hasAuthorship W4387408712A5075576655 @default.
- W4387408712 hasAuthorship W4387408712A5084529215 @default.
- W4387408712 hasBestOaLocation W43874087121 @default.
- W4387408712 hasConcept C104317684 @default.
- W4387408712 hasConcept C122927707 @default.
- W4387408712 hasConcept C142536801 @default.
- W4387408712 hasConcept C171089720 @default.
- W4387408712 hasConcept C184235292 @default.
- W4387408712 hasConcept C185592680 @default.
- W4387408712 hasConcept C2776175234 @default.
- W4387408712 hasConcept C2777229759 @default.
- W4387408712 hasConcept C2780124434 @default.
- W4387408712 hasConcept C53007507 @default.
- W4387408712 hasConcept C55493867 @default.
- W4387408712 hasConcept C86803240 @default.
- W4387408712 hasConcept C95444343 @default.
- W4387408712 hasConcept C97029542 @default.
- W4387408712 hasConceptScore W4387408712C104317684 @default.
- W4387408712 hasConceptScore W4387408712C122927707 @default.
- W4387408712 hasConceptScore W4387408712C142536801 @default.
- W4387408712 hasConceptScore W4387408712C171089720 @default.
- W4387408712 hasConceptScore W4387408712C184235292 @default.
- W4387408712 hasConceptScore W4387408712C185592680 @default.
- W4387408712 hasConceptScore W4387408712C2776175234 @default.
- W4387408712 hasConceptScore W4387408712C2777229759 @default.
- W4387408712 hasConceptScore W4387408712C2780124434 @default.
- W4387408712 hasConceptScore W4387408712C53007507 @default.
- W4387408712 hasConceptScore W4387408712C55493867 @default.