Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387408839> ?p ?o ?g. }
- W4387408839 abstract "The N13 component of somatosensory evoked potential (N13 SEP) represents the segmental response of cervical dorsal horn neurons. Neurophysiological studies in healthy participants showed that capsaicin-induced central sensitization causes an increase of the N13 SEP amplitude. Consequently, in human research, this spinal component may serve as a valuable readout of central sensitization. In this study, we wanted to verify if the sensitivity of the N13 SEP for detecting central sensitization is consistent across different experimental pain models inducing central sensitization and secondary hyperalgesia, namely high and low-frequency electrical stimulation (HFS and LFS). In 18 healthy participants, we recorded SEP after bilateral ulnar nerve stimulation before and after secondary hyperalgesia was induced through HFS and LFS applied on the ulnar nerve territory of the hand of one side. The area of secondary hyperalgesia was mapped with a calibrated 128-mN pinprick probe, and the mechanical pain sensitivity with three calibrated 16-64-256-mN pinprick probes. Although both HFS and LFS successfully induced secondary hyperalgesia only LFS increased the amplitude of the N13 SEP. These findings suggest that the sensitivity of the N13 SEP for detecting dorsal horn excitability changes may critically depend on the different experimental pain models. Our results indicate that LFS and HFS could trigger central sensitization at the dorsal horn level through distinct mechanisms, however this still needs confirmation by replication studies." @default.
- W4387408839 created "2023-10-07" @default.
- W4387408839 creator A5001799128 @default.
- W4387408839 creator A5018071089 @default.
- W4387408839 creator A5023398597 @default.
- W4387408839 creator A5023994461 @default.
- W4387408839 creator A5027144651 @default.
- W4387408839 creator A5045834162 @default.
- W4387408839 creator A5046961308 @default.
- W4387408839 creator A5053455937 @default.
- W4387408839 creator A5054828868 @default.
- W4387408839 creator A5088023508 @default.
- W4387408839 date "2023-10-01" @default.
- W4387408839 modified "2023-10-08" @default.
- W4387408839 title "Modulation of the spinal N13 SEP component by high- and low-frequency electrical stimulation. Experimental pain models matter" @default.
- W4387408839 cites W1869612208 @default.
- W4387408839 cites W1968015560 @default.
- W4387408839 cites W1990126819 @default.
- W4387408839 cites W2002099137 @default.
- W4387408839 cites W2002918384 @default.
- W4387408839 cites W2013994900 @default.
- W4387408839 cites W2027714949 @default.
- W4387408839 cites W2033001509 @default.
- W4387408839 cites W2036748976 @default.
- W4387408839 cites W2056060709 @default.
- W4387408839 cites W2064100996 @default.
- W4387408839 cites W2065704974 @default.
- W4387408839 cites W2070056571 @default.
- W4387408839 cites W2072592160 @default.
- W4387408839 cites W2082705609 @default.
- W4387408839 cites W2090521351 @default.
- W4387408839 cites W2092286924 @default.
- W4387408839 cites W2101341122 @default.
- W4387408839 cites W2141678708 @default.
- W4387408839 cites W2170019750 @default.
- W4387408839 cites W2315232423 @default.
- W4387408839 cites W2601911795 @default.
- W4387408839 cites W2766251233 @default.
- W4387408839 cites W3095025916 @default.
- W4387408839 cites W3138459365 @default.
- W4387408839 cites W3161372853 @default.
- W4387408839 cites W3194561337 @default.
- W4387408839 cites W3197254690 @default.
- W4387408839 cites W3203012133 @default.
- W4387408839 cites W3206350525 @default.
- W4387408839 cites W4298325719 @default.
- W4387408839 cites W4303192941 @default.
- W4387408839 doi "https://doi.org/10.1016/j.clinph.2023.08.022" @default.
- W4387408839 hasPublicationYear "2023" @default.
- W4387408839 type Work @default.
- W4387408839 citedByCount "0" @default.
- W4387408839 crossrefType "journal-article" @default.
- W4387408839 hasAuthorship W4387408839A5001799128 @default.
- W4387408839 hasAuthorship W4387408839A5018071089 @default.
- W4387408839 hasAuthorship W4387408839A5023398597 @default.
- W4387408839 hasAuthorship W4387408839A5023994461 @default.
- W4387408839 hasAuthorship W4387408839A5027144651 @default.
- W4387408839 hasAuthorship W4387408839A5045834162 @default.
- W4387408839 hasAuthorship W4387408839A5046961308 @default.
- W4387408839 hasAuthorship W4387408839A5053455937 @default.
- W4387408839 hasAuthorship W4387408839A5054828868 @default.
- W4387408839 hasAuthorship W4387408839A5088023508 @default.
- W4387408839 hasBestOaLocation W43874088391 @default.
- W4387408839 hasConcept C105702510 @default.
- W4387408839 hasConcept C126322002 @default.
- W4387408839 hasConcept C140530291 @default.
- W4387408839 hasConcept C152478114 @default.
- W4387408839 hasConcept C15490471 @default.
- W4387408839 hasConcept C15744967 @default.
- W4387408839 hasConcept C161941745 @default.
- W4387408839 hasConcept C169760540 @default.
- W4387408839 hasConcept C170493617 @default.
- W4387408839 hasConcept C172497186 @default.
- W4387408839 hasConcept C24998067 @default.
- W4387408839 hasConcept C2776217527 @default.
- W4387408839 hasConcept C2779245659 @default.
- W4387408839 hasConcept C3019020247 @default.
- W4387408839 hasConcept C42219234 @default.
- W4387408839 hasConcept C71924100 @default.
- W4387408839 hasConceptScore W4387408839C105702510 @default.
- W4387408839 hasConceptScore W4387408839C126322002 @default.
- W4387408839 hasConceptScore W4387408839C140530291 @default.
- W4387408839 hasConceptScore W4387408839C152478114 @default.
- W4387408839 hasConceptScore W4387408839C15490471 @default.
- W4387408839 hasConceptScore W4387408839C15744967 @default.
- W4387408839 hasConceptScore W4387408839C161941745 @default.
- W4387408839 hasConceptScore W4387408839C169760540 @default.
- W4387408839 hasConceptScore W4387408839C170493617 @default.
- W4387408839 hasConceptScore W4387408839C172497186 @default.
- W4387408839 hasConceptScore W4387408839C24998067 @default.
- W4387408839 hasConceptScore W4387408839C2776217527 @default.
- W4387408839 hasConceptScore W4387408839C2779245659 @default.
- W4387408839 hasConceptScore W4387408839C3019020247 @default.
- W4387408839 hasConceptScore W4387408839C42219234 @default.
- W4387408839 hasConceptScore W4387408839C71924100 @default.
- W4387408839 hasLocation W43874088391 @default.
- W4387408839 hasOpenAccess W4387408839 @default.
- W4387408839 hasPrimaryLocation W43874088391 @default.
- W4387408839 hasRelatedWork W1545290960 @default.
- W4387408839 hasRelatedWork W2012561402 @default.