FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387423071> ?p ?o ?g. }

• W4387423071 abstract "Our objective was to evaluate 30-day major adverse cardiac events (MACE) in emergency department (ED) patients with normal high-sensitivity troponins (hs-trop). We hypothesized that MACE rates would be <1% in patients with (1) two normal troponins regardless of change in troponin (delta) and (2) index hs-trop below the limit of quantitation (LOQ) regardless of the institution modified HEART score.This was a multicenter, retrospective, cohort study of adult patients who presented to 1 of 18 EDs between July 2020 and April 2021 with acute coronary syndrome as defined by an institutional-modified HEART score completed by their treating physician or midlevel, no evidence of ST-elevation myocardial infarction, and an index or serial gender-adjusted hs-trop within normal limits. The primary outcome was MACE within 30 days of index ED encounter. A detailed case review was then performed for those patients experiencing a MACE.Of the 9084 patients who had single or serial normal troponins, 31 (0.34%; confidence interval [CI] 0.23%-0.48%) experienced MACE. Of the 6140 patients with 2 normal hs-trop and a delta (change in troponin) <4, 27 patients (0.44%; CI 0.29%-0.64%) experienced MACE. Only 1 of the 69 patients with 2 normal hs-trop results but delta (change in troponin) ≥ 4 (1.45%; CI 0.04%-7.81%) suffered MACE. This patient was classified as non-low risk by our institutional HEART score. Of 7498 patients with an index hs-trop <LOQ, 14 (0.19%; CI 0.10%-0.31%) experienced MACE, with 57% (N = 8) deemed non-low risk by HEART score.Patients with 2 normal hs-trop values in the ED are unlikely to suffer 30-day MACE. Although it remains unclear whether patients with delta (change in troponin) ≥4 despite normal troponins will have a 30-day MACE, this situation is rare. Additionally, a single index hs-trop <6 ng/L demonstrated a low risk for 30-day MACE independent of the institutional HEART score." @default.
• W4387423071 created "2023-10-08" @default.
• W4387423071 creator A5002575279 @default.
• W4387423071 creator A5021588975 @default.
• W4387423071 creator A5030148918 @default.
• W4387423071 creator A5072796310 @default.
• W4387423071 creator A5081052865 @default.
• W4387423071 creator A5081975498 @default.
• W4387423071 creator A5083806342 @default.
• W4387423071 creator A5093021176 @default.
• W4387423071 creator A5093021177 @default.
• W4387423071 date "2023-10-01" @default.
• W4387423071 modified "2023-10-11" @default.
• W4387423071 title "Multicenter analysis to assess risk of major adverse cardiac events in patients undergoing high‐sensitivity troponin testing in the emergency department" @default.
• W4387423071 cites W1877338411 @default.
• W4387423071 cites W1989806937 @default.
• W4387423071 cites W1992798089 @default.
• W4387423071 cites W2069660427 @default.
• W4387423071 cites W2100541308 @default.
• W4387423071 cites W2120596490 @default.
• W4387423071 cites W2169735148 @default.
• W4387423071 cites W2255303552 @default.
• W4387423071 cites W2363398569 @default.
• W4387423071 cites W2587422788 @default.
• W4387423071 cites W2765432117 @default.
• W4387423071 cites W2908592887 @default.
• W4387423071 cites W2908751387 @default.
• W4387423071 cites W2915158039 @default.
• W4387423071 cites W2956003159 @default.
• W4387423071 cites W2963478010 @default.
• W4387423071 cites W3031098706 @default.
• W4387423071 cites W3097616345 @default.
• W4387423071 cites W3122939794 @default.
• W4387423071 cites W4280549753 @default.
• W4387423071 doi "https://doi.org/10.1002/emp2.13047" @default.
• W4387423071 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37811361" @default.
• W4387423071 hasPublicationYear "2023" @default.
• W4387423071 type Work @default.
• W4387423071 citedByCount "0" @default.
• W4387423071 crossrefType "journal-article" @default.
• W4387423071 hasAuthorship W4387423071A5002575279 @default.
• W4387423071 hasAuthorship W4387423071A5021588975 @default.
• W4387423071 hasAuthorship W4387423071A5030148918 @default.
• W4387423071 hasAuthorship W4387423071A5072796310 @default.
• W4387423071 hasAuthorship W4387423071A5081052865 @default.
• W4387423071 hasAuthorship W4387423071A5081975498 @default.
• W4387423071 hasAuthorship W4387423071A5083806342 @default.
• W4387423071 hasAuthorship W4387423071A5093021176 @default.
• W4387423071 hasAuthorship W4387423071A5093021177 @default.
• W4387423071 hasBestOaLocation W43874230711 @default.
• W4387423071 hasConcept C118552586 @default.
• W4387423071 hasConcept C126322002 @default.
• W4387423071 hasConcept C164705383 @default.
• W4387423071 hasConcept C207103383 @default.
• W4387423071 hasConcept C2777698277 @default.
• W4387423071 hasConcept C2780400711 @default.
• W4387423071 hasConcept C2780724011 @default.
• W4387423071 hasConcept C2780739214 @default.
• W4387423071 hasConcept C36036425 @default.
• W4387423071 hasConcept C44249647 @default.
• W4387423071 hasConcept C500558357 @default.
• W4387423071 hasConcept C71924100 @default.
• W4387423071 hasConceptScore W4387423071C118552586 @default.
• W4387423071 hasConceptScore W4387423071C126322002 @default.
• W4387423071 hasConceptScore W4387423071C164705383 @default.
• W4387423071 hasConceptScore W4387423071C207103383 @default.
• W4387423071 hasConceptScore W4387423071C2777698277 @default.
• W4387423071 hasConceptScore W4387423071C2780400711 @default.
• W4387423071 hasConceptScore W4387423071C2780724011 @default.
• W4387423071 hasConceptScore W4387423071C2780739214 @default.
• W4387423071 hasConceptScore W4387423071C36036425 @default.
• W4387423071 hasConceptScore W4387423071C44249647 @default.
• W4387423071 hasConceptScore W4387423071C500558357 @default.
• W4387423071 hasConceptScore W4387423071C71924100 @default.
• W4387423071 hasIssue "5" @default.
• W4387423071 hasLocation W43874230711 @default.
• W4387423071 hasLocation W43874230712 @default.
• W4387423071 hasOpenAccess W4387423071 @default.
• W4387423071 hasPrimaryLocation W43874230711 @default.
• W4387423071 hasRelatedWork W129132984 @default.
• W4387423071 hasRelatedWork W2013915456 @default.
• W4387423071 hasRelatedWork W2038729853 @default.
• W4387423071 hasRelatedWork W2054023746 @default.
• W4387423071 hasRelatedWork W2150800341 @default.
• W4387423071 hasRelatedWork W2417769256 @default.
• W4387423071 hasRelatedWork W2885100897 @default.
• W4387423071 hasRelatedWork W3008078763 @default.
• W4387423071 hasRelatedWork W4289535438 @default.
• W4387423071 hasRelatedWork W593240835 @default.
• W4387423071 hasVolume "4" @default.
• W4387423071 isParatext "false" @default.
• W4387423071 isRetracted "false" @default.
• W4387423071 workType "article" @default.