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• W4387424910 abstract "Abstract Disuse osteopenia is a well‐recognized consequence of prolonged physical inactivity, but its rate after orthopaedic injuries necessitating non‐weight‐bearing is not well studied. The purpose of this study was to estimate the rate of disuse osteopenia at the lumbar spine and proximal femur in patients with lower extremity trauma admitted to the hospital. We performed a retrospective chart review of patients with lower extremity trauma with a period of strict non‐weight‐bearing between completion of two computed tomography (CT) scans. The radiodensity of the proximal femur or lumbar vertebrae was measured from the earliest and latest available CT scans within the non‐weight‐bearing timeframe. The change in estimated bone mineral density (eBMD) was calculated as a proxy for disuse osteopenia. A total of 189,111 patients were screened, with 17 patients in the proximal femur group and 15 patients in the lumbar spine group meeting inclusion and exclusion criteria. The average rate of change in eBMD of the proximal femur was a decrease of 7.54 HU/day, 95% confidence interval (CI) [3.65, 11.43]. The average rate of change in eBMD of the lumbar spine was an increase of 1.45 HU/day, 95% CI [−3.15, 6.06]. In admitted, non‐weight‐bearing orthopaedic trauma patients, our novel study suggests that the proximal femur experiences disuse osteopenia during periods of non‐weight‐bearing, although this finding was not observed at the lumbar spine. The clinical significance of this data underscores the important consideration of disuse osteopenia by all physicians when caring for patients that may require non‐weight‐bearing restrictions." @default.
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• W4387424910 date "2023-10-14" @default.
• W4387424910 modified "2023-10-16" @default.
• W4387424910 title "The Rate of Disuse Osteopenia in Admitted, Non–Weight‐Bearing Patients" @default.
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• W4387424910 doi "https://doi.org/10.1002/jor.25713" @default.
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